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Journal Article
|Research

Genetic heterogeneity of hepatitis E virus in Darfur, Sudan, and neighboring Chad

Nicand E, Armstrong GL, Enouf V, Guthmann JP, Guerin JP, Caron M, Nizou JY, Andraghetti R
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Abstract
The within-outbreak diversity of hepatitis E virus (HEV) was studied during the outbreak of hepatitis E that occurred in Sudan in 2004. Specimens were collected from internally displaced persons living in a Sudanese refugee camp and two camps implanted in Chad. A comparison of the sequences in the ORF2 region of 23 Sudanese isolates and five HEV samples from the two Chadian camps displayed a high similarity (>99.7%) to strains belonging to Genotype 1. But four isolates collected in one of the Chadian camps were close to Genotype 2. Circulation of divergent strains argues for possible multiple sources of infection.

Countries

Chad

Subject Area

hepatitis Egenetics & genomics

Languages

English
DOI
10.1002/jmv.20487
Published Date
01 Dec 2005
PubMed ID
16254969
Journal
Journal of Medical Virology
Volume | Issue | Pages
Volume 77, Issue 4
Issue Date
2005-01-01
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Genetic heterogeneity of hepatitis E virus in Darfur, Sudan, and neighboring Chad | Journal Article / Research | MSF Science Portal