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endTB: finding shorter, less toxic, and more effective treatments for MDR-TB

endTB: finding shorter, less toxic, and more effective treatments for MDR-TB

The endTB project aims to find shorter, less toxic and more effective treatments for ‘multidrug-resistant TB’ (MDR-TB) through: 1) access to new drugs, 2) two clinical trials, and 3) advocacy at national and global levels.

The groundbreaking endTB clinical trial results were just published, where a personalized medicine approach highlights the benefits of a new shorter treatment strategy for extensively drug-resistant tuberculosis.

Read the new publication and over 40 research resources, publications, and protocol documents from the endTB project.

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Combatting neglected tropical diseases

Combatting neglected tropical diseases

Each year hundreds of thousands of people die from a neglected tropical disease, while many more suffer serious illness or lifelong disability. Yet as we mark World Neglected Tropical Diseases (NTD) Day on 30th January 2023, global progress towards eliminating these diseases is threatened by shifting global health priorities and declining investment in the wake of the Covid-19 pandemic.

The content collection linked below offers a snapshot of MSF’s work over the past two years on managing some of the most deadly NTDs, finding better tools and models of care for highly affected populations, and advocating for greater access to care and increased global funding. Several authors describe our programs and lessons learned from a decade of treating snakebite victims in sub-Saharan Africa. Two studies evaluate shorter, less toxic treatment for visceral leischmaniasis, while a policy analysis proposes critical steps towards eliminating this horrific disease in East Africa. Last, reports from Sokoto, Nigeria describe the collaborative development of a comprehensive model of care for noma.

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Mental health  in humanitarian settings

Mental health in humanitarian settings

Complex humanitarian emergencies and other low-resource settings can be exceedingly difficult places to provide quality mental health (MH) care. Yet these environments also often have a high burden of mental health care needs.

This collection presents a set of articles describing how MSF teams have adapted and evaluated ways of bringing clinically impactful MH care to neglected communities and patients—from forcibly displaced populations in northern Nigeria to Syrian refugees in Lebanon and typhoon survivors in the Philippines. It also highlights work on developing new tools for providing clinical supervision and for identifying those patients most in need of care in fragile settings, and on new approaches to delivering MH services during the Covid-19 pandemic.

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Find MSF Ethics Review Board documents here, and other MSF research and publication guidance documents here.


Featured Content

Editor’s Picks

Journal Article > Letter
British Medical Journal (BMJ)

Environmental changes in South Sudan are changing the fabric of people’s lives and steering humanitarian operations

23-Oct-2024
Journal Article > Research
Reproductive Health

Assessing post-abortion care using the WHO quality of care framework for maternal and newborn health: a cross-sectional study in two African hospitals in humanitarian settings

05-Aug-2024
Journal Article > Commentary
Lancet Global Health

The role of humanitarian actors in global governance for AMR

01-Jul-2024
Technical Report > Evidence Brief

Prevalence of active HCV infection and associated risk factors among members of Forcibly Displaced Myanmar National (FDMN) Population residing in camps, Cox’s Bazar, Bangladesh

01-Nov-2023
Journal Article > Research
PLOS Global Public Health

High caseload of Scabies amongst Rohingya refugees in Cox’s Bazar, Bangladesh: a retrospective analysis of the epidemiological and clinical characteristics of cases, July 2022 to November 2023

09-Apr-2025
Journal Article > Research
Lancet Global Health

24-week, all-oral regimens for pulmonary rifampicin-resistant tuberculosis in TB-PRACTECAL trial sites: an economic evaluation

01-Feb-2025
Journal Article > Research
New England Journal of Medicine

Oral regimens for rifampin-resistant, fluoroquinolone-susceptible tuberculosis

29-Jan-2025
Conference Material > Abstract
International Papillomavirus 2024

Scaling up cervical cancer screening in Southern Malawi: Screening models for difficult-to-reach populations

12-Nov-2024
Conference Material > Slide Presentation
MSF Scientific Days Asia 2024

Transforming MSF’s approach to community-led initiatives

08-Nov-2024
Technical Report > Policy Brief

Joint brief: The Lancet Countdown on Health and Climate Change & Médecins Sans Frontières

29-Oct-2024
Journal Article > Letter
British Medical Journal (BMJ)

Environmental changes in South Sudan are changing the fabric of people’s lives and steering humanitarian operations

23-Oct-2024
Journal Article > Research
Reproductive Health

Assessing post-abortion care using the WHO quality of care framework for maternal and newborn health: a cross-sectional study in two African hospitals in humanitarian settings

05-Aug-2024
Journal Article > Commentary
Lancet Global Health

The role of humanitarian actors in global governance for AMR

01-Jul-2024
Technical Report > Evidence Brief

Prevalence of active HCV infection and associated risk factors among members of Forcibly Displaced Myanmar National (FDMN) Population residing in camps, Cox’s Bazar, Bangladesh

01-Nov-2023
Journal Article > Research
PLOS Global Public Health

High caseload of Scabies amongst Rohingya refugees in Cox’s Bazar, Bangladesh: a retrospective analysis of the epidemiological and clinical characteristics of cases, July 2022 to November 2023

09-Apr-2025
Journal Article > Research
Lancet Global Health

24-week, all-oral regimens for pulmonary rifampicin-resistant tuberculosis in TB-PRACTECAL trial sites: an economic evaluation

01-Feb-2025
Journal Article > Research
New England Journal of Medicine

Oral regimens for rifampin-resistant, fluoroquinolone-susceptible tuberculosis

29-Jan-2025
Conference Material > Abstract
International Papillomavirus 2024

Scaling up cervical cancer screening in Southern Malawi: Screening models for difficult-to-reach populations

12-Nov-2024
Conference Material > Slide Presentation
MSF Scientific Days Asia 2024

Transforming MSF’s approach to community-led initiatives

08-Nov-2024
Technical Report > Policy Brief

Joint brief: The Lancet Countdown on Health and Climate Change & Médecins Sans Frontières

29-Oct-2024
Journal Article > Letter
British Medical Journal (BMJ)

Environmental changes in South Sudan are changing the fabric of people’s lives and steering humanitarian operations

23-Oct-2024
Journal Article > Research
Reproductive Health

Assessing post-abortion care using the WHO quality of care framework for maternal and newborn health: a cross-sectional study in two African hospitals in humanitarian settings

05-Aug-2024
Journal Article > Commentary
Lancet Global Health

The role of humanitarian actors in global governance for AMR

01-Jul-2024
Technical Report > Evidence Brief

Prevalence of active HCV infection and associated risk factors among members of Forcibly Displaced Myanmar National (FDMN) Population residing in camps, Cox’s Bazar, Bangladesh

01-Nov-2023

Newest Content

<
Journal Article > Review
World Journal of Surgery
Explosive Weapons Trauma Care Collective (EXTRACCT) blast injury clinical practice guideline: genito-urinary trauma
30-May-2025
Journal Article > Research
BMC Public Health
Reaching the “last mile”: describing community clinics implemented to increase COVID-19 vaccine uptake in Peel region, Canada
27-May-2025
Journal Article > Research
PLOS Global Public Health
End of treatment and 12-month post-treatment outcomes in patients treated with all-oral regimens for rifampicin-resistant tuberculosis in Ukraine: a prospective cohort study
23-May-2025
Journal Article > Research
PLOS One
Sequelae following an epidemic of meningococcal meningitis in Niger in 2022
22-May-2025
Journal Article > Research
New England Journal of Medicine
Intravenous rehydration for severe acute malnutrition with gastroenteritis
13-Jun-2025
Journal Article > Commentary
BMJ Opinion (blog)
Play has therapeutic power in healthcare and humanitarian settings
10-Jun-2025
Journal Article > Research
BMC Health Services Research
Assessment of water, sanitation and hygiene services within nineteen Rohingya camps in Cox’s Bazar, Bangladesh in 2022
09-Jun-2025
Journal Article > Research
American Journal of Tropical Medicine and Hygiene
Concomitant splenic tuberculosis and Epstein–Barr virus-related T-cell leukemia/lymphoma in a 28-year-old pregnant woman in South Sudan
04-Jun-2025
Journal Article > Review
World Journal of Surgery
Explosive Weapons Trauma Care Collective (EXTRACCT) blast injury clinical practice guideline: genito-urinary trauma
30-May-2025
Journal Article > Research
BMC Public Health
Reaching the “last mile”: describing community clinics implemented to increase COVID-19 vaccine uptake in Peel region, Canada
27-May-2025
Journal Article > Research
PLOS Global Public Health
End of treatment and 12-month post-treatment outcomes in patients treated with all-oral regimens for rifampicin-resistant tuberculosis in Ukraine: a prospective cohort study
23-May-2025
Journal Article > Research
PLOS One
Sequelae following an epidemic of meningococcal meningitis in Niger in 2022
22-May-2025
Journal Article > Research
New England Journal of Medicine
Intravenous rehydration for severe acute malnutrition with gastroenteritis
13-Jun-2025
Journal Article > Commentary
BMJ Opinion (blog)
Play has therapeutic power in healthcare and humanitarian settings
10-Jun-2025
Journal Article > Research
BMC Health Services Research
Assessment of water, sanitation and hygiene services within nineteen Rohingya camps in Cox’s Bazar, Bangladesh in 2022
09-Jun-2025
Journal Article > Research
American Journal of Tropical Medicine and Hygiene
Concomitant splenic tuberculosis and Epstein–Barr virus-related T-cell leukemia/lymphoma in a 28-year-old pregnant woman in South Sudan
04-Jun-2025
Journal Article > Review
World Journal of Surgery
Explosive Weapons Trauma Care Collective (EXTRACCT) blast injury clinical practice guideline: genito-urinary trauma
30-May-2025
Journal Article > Research
BMC Public Health
Reaching the “last mile”: describing community clinics implemented to increase COVID-19 vaccine uptake in Peel region, Canada
27-May-2025
Journal Article > Research
PLOS Global Public Health
End of treatment and 12-month post-treatment outcomes in patients treated with all-oral regimens for rifampicin-resistant tuberculosis in Ukraine: a prospective cohort study
23-May-2025
Journal Article > Research
PLOS One
Sequelae following an epidemic of meningococcal meningitis in Niger in 2022
22-May-2025
>