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Showing 1 - 20 of 32 Items
Showing 1 - 20 of 32 Items
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Journal Article
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Research

Diagnostic performance and kinetics of hepatitis E viral RNA and IgM antibody test positivity in a genotype 1 outbreak in South Sudan

Koyuncu A, Nesbitt R, Alvarez C, Asilaza KV, Wamala J,  et al.
2025-08-14 • Journal of Infectious Diseases
2025-08-14 • Journal of Infectious Diseases

BACKGROUND

Diagnostics are essential for understanding hepatitis E epidemiology, but the field performanc...

Conference Material
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Poster

The field performance of hepatitis E diagnostics during an outbreak in Bentiu, South Sudan

Koyuncu A, Nesbitt R, Alvarez C, 
Conference Material
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Poster

Dry blood spots as a practical alternative for confirming hepatitis E

Azman AS, Nesbitt R, Alvarez C, Asilaza KV, Wamala J,  et al.
2025-05-22 • MSF Scientific Days International 2025
Journal Article
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Research
Journal Article
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Research
Journal Article
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Research
Conference Material
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Abstract
Conference Material
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Abstract
Conference Material
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Video

First mass reactive vaccination campaign against Hepatitis E: main results of observational studies

Gignoux EM
2024-05-23 • Epicentre Scientific Day 2024
2024-05-23 • Epicentre Scientific Day 2024
Conference Material
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Video

Safety of hepatitis E vaccine in pregnancy emulating a target trial following a mass reactive vaccination campaign in South Sudan

Gignoux EM
2024-05-16 • MSF Scientific Day International 2024
2024-05-16 • MSF Scientific Day International 2024
Conference Material
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Slide Presentation
Conference Material
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Abstract
Journal Article
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Research
Conference Material
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Abstract
Conference Material
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Video

Safety of hepatitis E vaccination in pregnancy following the first mass reactive vaccination campaign in Bentiu, South Sudan

Nesbitt RC
2023-06-08 • Epicentre Scientific Day Paris 2023
2023-06-08 • Epicentre Scientific Day Paris 2023
Conference Material
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Abstract
Conference Material
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Poster
Conference Material
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Slide Presentation
Conference Material
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Video

Two-dose vaccine effectiveness following the first reactive mass vaccination campaign against Hepatitis E in Bentiu, South Sudan

Asilaza VK
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023
Journal Article
|
Letter
Asilaza KV, 
Wamala J, 
et al.
2025-05-22 • MSF Scientific Days International 2025
2025-05-22 • MSF Scientific Days International 2025
2025-05-22 • MSF Scientific Days International 2025

High confidence and demand for hepatitis E vaccine during an outbreak in Bentiu, South Sudan: A qualitative study

Koyuncu A, Asilaza KV, Rumunu J, Wamala J, Gitahi P,  et al.
2025-03-06 • PLOS Global Public Health
2025-03-06 • PLOS Global Public Health

In 2021 in response to an outbreak of hepatitis E in Bentiu internally displaced persons camp the South Sudanese Ministry of Health with support from Médecins Sans Frontières implemen...

The effectiveness of two doses of recombinant hepatitis E vaccine in response to an outbreak in Bentiu, South Sudan: a case–control and bias indicator study

Nesbitt RC, Kinya Asilaza V, Alvarez C, Gitahi P, Nkemenang P,  et al.
2025-01-08 • Lancet Infectious Diseases
2025-01-08 • Lancet Infectious Diseases

BACKGROUND

Hepatitis E virus (HEV) is a leading cause of acute viral hepatitis, particularly in Asia and Africa, where HEV genotypes 1 and 2 are prevalen...

Safety of hepatitis E vaccine in pregnancy: an emulated target trial following a mass reactive vaccination campaign in Bentiu internally displaced persons camp, South Sudan

Nesbitt RC, Azman AS, Asilaza VK, Edwards JK, Gitahi P,  et al.
2024-11-01 • Lancet Global Health
2024-11-01 • Lancet Global Health

Hepatitis E outbreak response in Fangak County, South Sudan: coverage and acceptance of a vaccination campaign targeting women of reproductive age

Aumuller J
2024-05-23 • Epicentre Scientific Day 2024
2024-05-23 • Epicentre Scientific Day 2024
BACKGROUND
In September 2023, the South Sudan Ministry of Health declared an outbreak of hepatitis E virus in Fangak County, Jonglei State. From April to November 2023, MSF identifie...

First mass reactive vaccination campaign against Hepatitis E: main results of observational studies

Gignoux EM
2024-05-23 • Epicentre Scientific Day 2024
2024-05-23 • Epicentre Scientific Day 2024

BACKGROUND

Hepatitis E was first identified in the 1990s, but major epidemics date back to the 1950s. There is no specific treatment, and it can be fatal especially for pregnant...

Safety of hepatitis E vaccine in pregnancy: emulating a target trial following a mass reactive vaccination campaign in South Sudan

Nesbitt R, Azman AS, Asilaza VK, Edwards JK, Nkemenang P,  et al.
2024-05-16 • MSF Scientific Day International 2024
2024-05-16 • MSF Scientific Day International 2024

Safety of hepatitis E vaccine in pregnancy: emulating a target trial following a mass reactive vaccination campaign in South Sudan

Nesbitt R, Azman AS, Asilaza VK, Edwards JK, Nkemenang P,  et al.
2024-05-16 • MSF Scientific Day International 2024
2024-05-16 • MSF Scientific Day International 2024

INTRODUCTION

Hepatitis E causes high mortality among pregnant women, with case fatality risks over 30% and adverse fetal outcomes. There is an evidence gap on the safety of the ...

Vaccination coverage and adverse events following a reactive vaccination campaign against hepatitis E in Bentiu displaced persons camp, South Sudan

Nesbitt RC, Asilaza VK, Gignoux EM, Koyuncu A, Gitahi P,  et al.
2024-01-22 • PLOS Neglected Tropical Diseases
2024-01-22 • PLOS Neglected Tropical Diseases

INTRODUCTION

Hepatitis E (HEV) genotypes 1 and 2 are the common cause of jaundice and acute viral hepatitis that can cause large-scale outbreaks. HEV infection...

Safety of hepatitis E vaccination in pregnancy following the first mass reactive vaccination campaign in Bentiu, South Sudan

Nesbitt RC
2023-06-08 • Epicentre Scientific Day Paris 2023
2023-06-08 • Epicentre Scientific Day Paris 2023
BACKGROUND
Hepatitis E causes high mortality among pregnant women with case fatality risks of 10-25%, and adverse fetal outcomes. Hecolin® is a safe and efficacious vaccine against H...

Two-dose vaccine effectiveness following the first reactive mass vaccination campaign against hepatitis E in Bentiu, South Sudan

Nesbitt RC, Rumunu J, Asilaza VK, Gitahi P, Nkemenang P,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023
INTRODUCTION
A three-dose recombinant vaccine against hepatitis E, Hecolin, has been licensed for use in China since 2011. While not recommended for routine use due to lack of eviden...

Vaccination coverage and adverse events following immunisation after the first reactive mass vaccination campaign against Hepatitis E in Bentiu, South Sudan

Nesbitt RC, Rumunu J, Asilaza VK, Gitahi P, Nkemenang P,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023

Two-dose vaccine effectiveness following the first reactive mass vaccination campaign against Hepatitis E in Bentiu, South Sudan

Nesbitt RC, Rumunu J, Asilaza VK, Gitahi P, Nkemenang P,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023

Hepatitis E virus outbreak among Tigray War refugees from Ethopia, Sudan

Azman AS, Gignoux E, Nesbitt R, Rumunu J, Aggarwal R,  et al.
2023-02-01 • Emerging Infectious Diseases
2023-02-01 • Emerging Infectious Diseases