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Journal Article
|Research

Early prediction of treatment efficacy in Second-Stage Gambiense Human African Trypanosomiasis

Priotto G, Chappuis F, Bastard M, Flevaud L, Etard JF
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Abstract
Human African trypanosomiasis is fatal without treatment. The long post-treatment follow-up (24 months) required to assess cure complicates patient management and is a major obstacle in the development of new therapies. We analyzed individual patient data from 12 programs conducted by Médecins Sans Frontières in Uganda, Sudan, Angola, Central African Republic, Republic of Congo and Democratic Republic of Congo searching for early efficacy indicators.

Countries

Angola Central African Republic Congo-Brazzaville Democratic Republic of Congo Uganda Sudan

Subject Area

neglected tropical diseasessleeping sickness

Languages

English
DOI
10.1371/journal.pntd.0001662
Published Date
05 Jun 2012
PubMed ID
22701752
Journal
PLOS Neglected Tropical Diseases
Volume | Issue | Pages
Volume 6, Issue 6
Issue Date
2012-06-05
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Early prediction of treatment efficacy in Second-Stage Gambiense Human African Trypanosomiasis | Journal Article / Research | MSF Science Portal