Baudin E, Mordt OV, Alves D, Seixas J, Lemerani M, et al.
2024-05-16 • MSF Scientific Day International 2024
2024-05-16 • MSF Scientific Day International 2024
INTRODUCTION Trypanosoma brucei rhodesiense human African trypanosomiasis (r-HAT), the zoonotic, acute form of sleeping sickness in eastern Africa, is lethal if untreated. Today, onl...
Santos ALS, Rodrigues IA, d’Avila-Levy CM, Sodré CL, Ritmeijer KKD, et al.
2023-10-19 • Pathogens
2023-10-19 • Pathogens
Human African trypanosomiasis (also known as sleeping sickness, with Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense as etiological agents), American trypanosomiasis (als...
Robays J, Ebeja Kadima A, Lutumba P, Miaka mia Bilenge C, Kande Betu Ku Mesu V, et al.
2004-08-01 • Tropical Medicine and International Health
2004-08-01 • Tropical Medicine and International Health
BACKGROUND: Increasing numbers of human African trypanosomiasis (HAT) cases have been reported in urban residents of Kinshasa, Democratic Republic Congo since 1996. We set up a case-cont...
Checchi F, Funk S, Chandramohan D, Haydon DT, Chappuis F
2015-07-04 • BMC Research Notes
2015-07-04 • BMC Research Notes
BACKGROUND The duration of the stages of HAT is an important factor in epidemiological studies and intervention planning. Previously, we published estimates of the duration of the ha...
Schmid C, Kuemmerle A, Blum J, Ghabri S, Kande V, et al.
2012-11-29 • PLOS Neglected Tropical Diseases
2012-11-29 • PLOS Neglected Tropical Diseases
Trypanosoma brucei (T.b.) gambiense Human African trypanosomiasis (HAT; sleeping sickness) is a fatal disease. Until 2009, available treatments for 2(nd) stage HAT were complicated to us...
Burri C, Yeramian PD, Allen JL, Merolle A, Serge KK, et al.
2016-02-16 • PLOS Neglected Tropical Diseases
2016-02-16 • PLOS Neglected Tropical Diseases
BACKGROUND Sleeping sickness (human African trypanosomiasis [HAT]) is caused by protozoan parasites and characterized by a chronic progressive course, which may last up to several ye...
Tong J, Valverde O, Mahoudeau C, Yun O, Chappuis F
2011-05-26 • Conflict and Health
2011-05-26 • Conflict and Health
Human African trypanosomiasis (HAT), or sleeping sickness, is a fatal neglected tropical disease if left untreated. HAT primarily affects people living in rural sub-Saharan Africa, often...
Kwedi Nolna S, Ntone R, Fouda Mbarga N, Mbainda S, Mutangala W, et al.
2020-11-17 • Tropical Medicine and Infectious Disease
2020-11-17 • Tropical Medicine and Infectious Disease
BACKGROUND Based on the premise that Africans in rural areas seek health care from traditional healers, this study investigated a collaborative model between traditional healers and...
Human African trypanosomiasis (sleeping sickness) occurs in sub-Saharan Africa. It is caused by the protozoan parasite Trypanosoma brucei, transmitted by tsetse flies. Almost all cases a...
Alirol E, Schrumpf D, Amici Heradi J, Riedel A, de Patoul C, et al.
2013-01-01 • Clinical Infectious Diseases
2013-01-01 • Clinical Infectious Diseases
BACKGROUND Existing diagnostic and treatment tools for human African trypanosomiasis (HAT) are limited. The recent development of nifurtimox-eflornithine combination therapy (NECT) h...
Human African trypanosomiasis (HAT), or sleeping sickness, is a vector-borne disease that flourishes in impoverished, rural parts of sub-Saharan Africa. It is caused by infection with th...
Checchi F, Chappuis F, Karunakara U, Priotto G, Chandramohan D
2011-07-05 • PLOS Neglected Tropical Diseases
2011-07-05 • PLOS Neglected Tropical Diseases
Algorithms to diagnose gambiense human African trypanosomiasis (HAT, sleeping sickness) are often complex due to the unsatisfactory sensitivity and/or specificity of available tests, and...
