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Showing 1 - 20 of 111 Items
Showing 1 - 20 of 111 Items
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Journal Article
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Short Report

Defining the noma research agenda

Galli A, Comparet M, Dagne DA, Baratti-Mayer D, Cao TH,  et al.
2025-04-21 • PLOS Neglected Tropical Diseases
2025-04-21 • PLOS Neglected Tropical Diseases
  • A 1-day symposium brought together over 100 individuals with lived experience of noma, expertise in neglected tropical diseases, and public health, including researchers, health ...
Journal Article
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Research

Patient insights research exploring disease awareness, patient life experience, and current management of visceral leishmaniasis in Bihar, India

Sundar S, Alves F, Ritmeijer K, den Boer M, Forsyth C,  et al.
2025-02-25 • PLOS Neglected Tropical Diseases
2025-02-25 • PLOS Neglected Tropical Diseases

BACKGROUND

Visceral leishmaniasis (VL) is a vector-borne disease caused by Leishmania parasites and transmitted by sand fly bites, targeted for elimination in I...

Journal Article
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Research

Impact of a multi-pronged cholera intervention in an endemic setting

Blake A, Walder A, Hanks EM, Welo PO, Luquero F,  et al.
2025-02-19 • PLOS Neglected Tropical Diseases
2025-02-19 • PLOS Neglected Tropical Diseases

Cholera is a bacterial water-borne diarrheal disease transmitted via the fecal-oral route that causes high morbidity in sub-Saharan Africa and Asia. It is preventable with vaccination...

Journal Article
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Research

The economic burden of visceral leishmaniasis and barriers to accessing healthcare in Tigray, North Ethiopia: A field based study

Tessema SB, Hagos T, Kehasy G, Paintain L, Adera C,  et al.
2024-10-15 • PLOS Neglected Tropical Diseases
2024-10-15 • PLOS Neglected Tropical Diseases

BACKGROUND

Visceral leishmaniasis (VL) is an important public health problem, which mainly affects the poor rural dwelling communities in Low- and Middle-Income...

Journal Article
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Research

A preliminary indication that HLA-A*03:01 may be associated with visceral leishmaniasis development in people living with HIV in Ethiopia

de Vrij N, Vandoren R, Ramadan K, Van Hul A, Ceulemans A,  et al.
2024-09-30 • PLOS Neglected Tropical Diseases
2024-09-30 • PLOS Neglected Tropical Diseases

Human immunodeficiency virus (HIV) co-infection is a major challenge for visceral leishmaniasis (VL) control, particularly in Ethiopia where the incidence of both pathogens is high. V...

Journal Article
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Research

Neglected etiologies of prolonged febrile illnesses in tropical and subtropical regions: A systematic review

Musumeci S, Kruse A, Chappuis F, Ostergaard Jensen T, Alcoba G
2024-06-21 • PLOS Neglected Tropical Diseases
2024-06-21 • PLOS Neglected Tropical Diseases
BACKGROUND
Febrile illnesses that persist despite initial treatment are common clinical challenges in (sub)tropical low-resource settings. Our aim is to review infectious etiologies ...
Journal Article
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Research

A phase II, non-comparative randomised trial of two treatments involving liposomal amphotericin B and miltefosine for post-kala-azar dermal leishmaniasis in India and Bangladesh

Sundar S, Pandey K, Mondal D, Madhukar M, Kamal Topno R,  et al.
2024-06-20 • PLOS Neglected Tropical Diseases
2024-06-20 • PLOS Neglected Tropical Diseases
BACKGROUND
In Southeast Asia, treatment is recommended for all patients with post-kala-azar dermal leishmaniasis (PKDL). Adherence to the first-line regimen, twelve weeks of miltefos...
Journal Article
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Research

Vaccination coverage and adverse events following a reactive vaccination campaign against hepatitis E in Bentiu displaced persons camp, South Sudan

Nesbitt RC, Asilaza VK, Gignoux EM, Koyuncu A, Gitahi P,  et al.
2024-01-22 • PLOS Neglected Tropical Diseases
2024-01-22 • PLOS Neglected Tropical Diseases

INTRODUCTION

Hepatitis E (HEV) genotypes 1 and 2 are the common cause of jaundice and acute viral hepatitis that can cause large-scale outbreaks. HEV infection...

Journal Article
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Research

Real life condition evaluation of Inoserp PAN-AFRICA antivenom effectiveness in Cameroon

Chippaux JP, Ntone R, Benhammou D, Madec Y, Noël G,  et al.
2023-11-08 • PLOS Neglected Tropical Diseases
2023-11-08 • PLOS Neglected Tropical Diseases
BACKGROUND
Snakebites is a serious public health issue but remains a neglected tropical disease. Data on antivenom effectiveness are urgently needed in Africa. We assessed effectiven...
Journal Article
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Research

Proportion of paediatric admissions with any stage of noma at the Anka General Hospital, northwest Nigeria

Farley ES, Karinja MN, Lawal AM, Olaleye M, Muhammad S,  et al.
2023-10-27 • PLOS Neglected Tropical Diseases
2023-10-27 • PLOS Neglected Tropical Diseases
INTRODUCTION
Noma is a rapidly spreading infection of the oral cavity which mainly affects young children. Without early treatment, it can have a high mortality rate. Simple gingivit...
Journal Article
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Commentary

Anticipating visceral leishmaniasis epidemics due to the conflict in Northern Ethiopia

Boodman C, van Griensven J, Gupta N, Diro EGJ, Ritmeijer KKD
2023-03-23 • PLOS Neglected Tropical Diseases
2023-03-23 • PLOS Neglected Tropical Diseases
Journal Article
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Commentary

Hepatitis E vaccine—Illuminating the barriers to use

Lynch JA, Lim JK, Asaga PEP, Wartel TA, Marti M,  et al.
2023-01-05 • PLOS Neglected Tropical Diseases
2023-01-05 • PLOS Neglected Tropical Diseases
Journal Article
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Commentary

Understanding and tackling snakebite envenoming with transdisciplinary research

Gutiérrez JM, Borri J, Giles-Vernick T, Duda R, Habib AG,  et al.
2022-11-17 • PLOS Neglected Tropical Diseases
2022-11-17 • PLOS Neglected Tropical Diseases
Journal Article
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Research

Prevalence and determinants of asymptomatic Leishmania infection in HIV-infected individuals living within visceral leishmaniasis endemic areas of Bihar, India

Mahajan R, Owen SI, Kumar S, Pandey K, Kazmi S,  et al.
2022-08-30 • PLOS Neglected Tropical Diseases
2022-08-30 • PLOS Neglected Tropical Diseases
People living with HIV (PLHIV) have an increased risk of developing visceral leishmaniasis (VL) and poor outcomes compared to HIV negative individuals. Here, we aim to establish the prev...
Journal Article
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Research

The increasing incidence of visceral leishmaniasis relapse in South Sudan: A retrospective analysis of field patient data from 2001–2018

Naylor-Leyland G, Collin SM, Gatluak F, den Boer ML, Alves F,  et al.
2022-08-18 • PLOS Neglected Tropical Diseases
2022-08-18 • PLOS Neglected Tropical Diseases
BACKGROUND
Visceral Leishmaniasis (VL) is endemic in South Sudan, manifesting periodically in major outbreaks. Provision of treatment during endemic periods and as an emergency respo...
Journal Article
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Research

An artificial intelligence model to identify snakes from across the world: Opportunities and challenges for global health and herpetology

Bolon I, Picek L, Durso AM, Alcoba G, Chappuis F,  et al.
2022-08-15 • PLOS Neglected Tropical Diseases
2022-08-15 • PLOS Neglected Tropical Diseases
BACKGROUND
Snakebite envenoming is a neglected tropical disease that kills an estimated 81,000 to 138,000 people and disables another 400,000 globally every year. The World Health Or...
Journal Article
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Research

Urban yellow fever outbreak—Democratic Republic of the Congo, 2016: Towards more rapid case detection

Ingelbeen B, Weregemere NA, Noel H, Tshapenda G, Mossoko M,  et al.
2018-12-07 • PLOS Neglected Tropical Diseases
2018-12-07 • PLOS Neglected Tropical Diseases

BACKGROUND

Between December 2015 and July 2016, a yellow fever (YF) outbreak affected urban areas of Angola and the Democratic Republic of the Congo (DRC). We described the outb...

Journal Article
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Commentary

Generating evidence to improve the response to neglected diseases: how operational research in a Médecins Sans Frontières Buruli ulcer treatment programme informed international management guidance

O'Brien DP, Ford NP, Vitoria M, Asiedu K, Calmy A,  et al.
2015-11-12 • PLOS Neglected Tropical Diseases
2015-11-12 • PLOS Neglected Tropical Diseases
Journal Article
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Research

Pregnancy outcomes after a mass vaccination campaign with an oral cholera vaccine in Guinea: a retrospective cohort study

Grout L, Martinez-Pino I, Ciglenecki I, Keita S, Diallo AK,  et al.
2015-12-29 • PLOS Neglected Tropical Diseases
2015-12-29 • PLOS Neglected Tropical Diseases
INTRODUCTION
Since 2010, WHO has recommended oral cholera vaccines as an additional strategy for cholera control. During a cholera episode, pregnant women are at high risk of complic...
Journal Article
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Review

Noma (cancrum oris): A scoping literature review of a neglected disease (1843 to 2021)

Farley ES, Mehta UC, Srour ML, Lenglet AD
2021-12-14 • PLOS Neglected Tropical Diseases
2021-12-14 • PLOS Neglected Tropical Diseases
BACKGROUND
Noma (cancrum oris) is an ancient but neglected and poorly understood preventable disease, afflicting the most disenfranchised populations in the world. It is a devastatin...