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Copyright © Médecins Sans Frontières
v2.1.5153.produseast1
Showing 1 - 20 of 22 Items
Showing 1 - 20 of 22 Items
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Journal Article
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Review

Carriage of third-generation cephalosporin-resistant and carbapenem-resistant Enterobacterales among children in sub-Saharan Africa: a systematic review and meta-analysis

Ruef M, Emonet S, Merglen A, Dewez JE, Obama BM,  et al.
2024-03-11 • eClinicalMedicine
2024-03-11 • eClinicalMedicine
BACKGROUND
The increasing resistance of Enterobacterales to third-generation cephalosporins and carbapenems in sub-Saharan Africa (SSA) is a major public health concern. We did a sys...
Journal Article
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Review

Antimicrobial resistance in Enterobacterales infections among children in sub-Saharan Africa: a systematic review and meta-analysis

Kowalski M, Minka Obama B, Catho G, Dewez JE, Merglen A,  et al.
2024-03-08 • eClinicalMedicine
2024-03-08 • eClinicalMedicine
BACKGROUND
The burden of antimicrobial resistance (AMR) has been estimated to be the highest in sub-Saharan Africa (SSA). The current study estimated the proportion of drug-resistant...
Journal Article
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Research

Cholera outbreaks in sub-Saharan Africa during 2010-2019: a descriptive analysis

Zheng Q, Luquero FJ, Ciglenecki I, Wamala JF, Abubakar A,  et al.
2022-09-01 • International Journal of Infectious Diseases
2022-09-01 • International Journal of Infectious Diseases
BACKGROUND
Cholera remains a public health threat but is inequitably distributed across sub-Saharan Africa. Lack of standardized reporting and inconsistent outbreak definitions limit...
Journal Article
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Research

Provision of antiretroviral treatment in conflict settings: the experience of Médecins Sans Frontières

O'Brien DP, Venis S, Greig J, Shanks L, Ellman T,  et al.
2010-06-17 • Conflict and Health
2010-06-17 • Conflict and Health
INTRODUCTION
Many countries ravaged by conflict have substantial morbidity and mortality attributed to HIV/AIDS yet HIV treatment is uncommonly available. Universal access to HIV car...
Journal Article
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Research

Mortality among displaced former UNITA members and their families in Angola: a retrospective cluster survey

Grein T
2003-09-20 • British Medical Journal (BMJ)
2003-09-20 • British Medical Journal (BMJ)
OBJECTIVE
To measure retrospectively mortality among a previously inaccessible population of former UNITA members and their families displaced within Angola, before and after their a...
Journal Article
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Research

Effectiveness of melarsoprol and eflornithine as first-line regimens for gambiense sleeping sickness in nine Médecins Sans Frontières programmes

Balasegaram M, Young H, Chappuis F, Priotto G, Raguenaud ME,  et al.
2008-10-21 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2008-10-21 • Transactions of the Royal Society of Tropical Medicine and Hygiene
This paper describes the effectiveness of first-line regimens for stage 2 human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense infection in nine Médecins Sans Frontièr...
Journal Article
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Research

Simplifying switch to second-line antiretroviral therapy in sub Saharan Africa: predicted effect of using a single viral load to define efavirenz-based first-line failure

Shroufi A, van Cutsem G, Cambiano V, Bansi-Matharu L, Duncan K,  et al.
2019-08-01 • AIDS
2019-08-01 • AIDS
BACKGROUND
Many individuals failing first-line antiretroviral therapy (ART) in sub-Saharan Africa never initiate second-line ART or do so after significant delay. For people on ART w...
Journal Article
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Research

High efficacy of two artemisinin-based combinations (artesunate + amodiaquine and artemether + lumefantrine) in Caala, Central Angola

Guthmann JP, Cohuet S, Rigutto C, Fortes F, Saraiva N,  et al.
2006-07-01 • American Journal of Tropical Medicine and Hygiene
2006-07-01 • American Journal of Tropical Medicine and Hygiene
In April 2004, 137 children 6-59 months of age with uncomplicated Plasmodium falciparum (Pf) malaria (Caala, Central Angola) were randomized to receive either artemether-lumefantrine (Co...
Journal Article
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Research

Efficacy of artesunate-amodiaquine for treating uncomplicated falciparum malaria in sub-Saharan Africa: a multi-centre analysis

Zwang J, Olliaro PL, Barennes H, Bonnet MMB, Brasseur P,  et al.
2009-08-23 • Malaria Journal
2009-08-23 • Malaria Journal
BACKGROUND: Artesunate and amodiaquine (AS&AQ) is at present the world's second most widely used artemisinin-based combination therapy (ACT). It was necessary to evaluate the efficacy of...
Journal Article
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Research

Efficacy, Safety, and Dose of Pafuramidine, a New Oral Drug for Treatment of First Stage Sleeping Sickness, in a Phase 2a Clinical Study and Phase 2b Randomized Clinical Studies

Burri C, Yeramian PD, Allen JL, Merolle A, Serge KK,  et al.
2016-02-16 • PLOS Neglected Tropical Diseases
2016-02-16 • PLOS Neglected Tropical Diseases
BACKGROUND
Sleeping sickness (human African trypanosomiasis [HAT]) is caused by protozoan parasites and characterized by a chronic progressive course, which may last up to several ye...
Journal Article
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Commentary

Angola's suffering behind a pretence of normality

Stokes C, Ford NP, Sanchez O, Perrin JM, Poncin M,  et al.
2000-12-16 • Lancet
2000-12-16 • Lancet
Journal Article
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Research

Low and deficient niacin status and pellagra are endemic in postwar Angola

Seal AJ, Creeke PI, Dibari F, Cheung E, Kyroussis E,  et al.
2007-01-01 • American Journal of Clinical Nutrition
2007-01-01 • American Journal of Clinical Nutrition
BACKGROUND
Outbreaks of pellagra were documented during the civil war in Angola, but no contemporary data on the incidence of pellagra or the prevalence of niacin deficiency were ava...
Journal Article
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Research

Decreased peripheral health service utilisation during an outbreak of Marburg haemorrhagic fever, Uíge, Angola, 2005

Roddy P, Marchiol A, Jeffs B, Palma PP, Bernal O,  et al.
2008-10-04 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2008-10-04 • Transactions of the Royal Society of Tropical Medicine and Hygiene
In 2005, a Marburg haemorrhagic fever (MHF) outbreak occurred in Uíge province, Angola, which had its epicentre in Uíge municipality. Concurrently, a health facility located a considerab...
Journal Article
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Research

Moving towards malaria elimination: trends and attributes of cases in Kavango region, Namibia, 2010-2014

Nghipumbwa MH, Ade S, Kizito W, Takarinda KC, Uusiku P,  et al.
2018-04-25 • Public Health Action
2018-04-25 • Public Health Action
Setting: Kavango, a 'moderate' transmission risk region located in north-eastern Namibia, borders Angola, a country with higher malaria transmission levels. Objective: To determine 1) th...
Journal Article
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Research

The use of a mobile laboratory unit in support of patient management and epidemiological surveillance during the 2005 Marburg outbreak in Angola

Grolla A, Jones SM, Fernando L, Strong JE, Stroher U,  et al.
2011-05-24 • PLOS Neglected Tropical Diseases
2011-05-24 • PLOS Neglected Tropical Diseases
Background: Marburg virus (MARV), a zoonotic pathogen causing severe hemorrhagic fever in man, has emerged in Angola resulting in the largest outbreak of Marburg hemorrhagic fever (MHF) ...
Journal Article
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Research

The Medecins Sans Frontieres intervention in the Marburg hemorrhagic fever epidemic, Uige, Angola, 2005. II. lessons learned in the community

Roddy P, Weatherill D, Jeffs B, Abaakouk Z, Dorion C,  et al.
2007-11-15 • Journal of Infectious Diseases
2007-11-15 • Journal of Infectious Diseases
From 27 March 2005 onwards, the independent humanitarian medical aid agency Medecins Sans Frontieres, together with the World Health Organization, the Angolan Ministry of Health, and oth...
Journal Article
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Research

Whole blood NAD and NADP concentrations are not depressed in subjects with clinical pellagra

Creeke PI, Dibari F, Cheung E, van den Briel T, Kyroussis E,  et al.
2007-09-01 • Journal of Nutrition
2007-09-01 • Journal of Nutrition
Population surveys for niacin deficiency are normally based on clinical signs or on biochemical measurements of urinary niacin metabolites. Status may also be determined by measurement o...
Journal Article
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Research

Mental health in HIV-positive pregnant women: results from Angola

Bernatsky S, Souza R, de Jong K
2007-05-01 • AIDS Care
2007-05-01 • AIDS Care
Our objective was to assess the mental health status of pregnant women who are HIV-positive, compared with other groups of pregnant women. We evaluated pregnant HIV-positive women attend...
Journal Article
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Research

Different methodological approaches to the assessment of in vivo efficacy of three artemisinin-based combination antimalarial treatments for the treatment of uncomplicated falciparum malaria in African children

Ashley EA, Pinoges LLP, Turyakira E, Dorsey G, Checchi F,  et al.
2008-08-09 • Malaria Journal
2008-08-09 • Malaria Journal
BACKGROUND: Use of different methods for assessing the efficacy of artemisinin-based combination antimalarial treatments (ACTs) will result in different estimates being reported, with im...
Journal Article
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Research

Early prediction of treatment efficacy in Second-Stage Gambiense Human African Trypanosomiasis

Priotto G, Chappuis F, Bastard M, Flevaud L, Etard JF
2012-06-05 • PLOS Neglected Tropical Diseases
2012-06-05 • PLOS Neglected Tropical Diseases
Human African trypanosomiasis is fatal without treatment. The long post-treatment follow-up (24 months) required to assess cure complicates patient management and is a major obstacle in ...