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Towards More Accurate HIV Testing in Sub-Saharan Africa: a Multi-Site Evaluation of HIV RDTs and Risk Factors For False Positives | Journal Article / Research | MSF Science Portal
Journal Article
|Research

Towards More Accurate HIV Testing in Sub-Saharan Africa: a Multi-Site Evaluation of HIV RDTs and Risk Factors For False Positives

Kosack CS, Page AL, Beelaert G, Benson TT, Savane A, Nganga M, Andre B, Zahinda JB, Shanks L, Fransen K
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Abstract
Although individual HIV rapid diagnostic tests (RDTs) show good performance in evaluations conducted by WHO, reports from several African countries highlight potentially significant performance issues. Despite widespread use of RDTs for HIV diagnosis in resource-constrained settings, there has been no systematic, head-to-head evaluation of their accuracy with specimens from diverse settings across sub-Saharan Africa. We conducted a standardized, centralized evaluation of eight HIV RDTs and two simple confirmatory assays at a WHO collaborating centre for evaluation of HIV diagnostics using specimens from six sites in five sub-Saharan African countries.

Countries

Cameroon Democratic Republic of Congo Guinea Kenya Uganda

Subject Area

diagnosticsHIV/AIDS

Languages

English
Published Date
22 Mar 2017
PubMed ID
28364560
Journal
Journal of the International AIDS Society
Volume | Issue | Pages
Volume null Issue 1
Issue Date
2017-01-01