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Showing 1 - 20 of 189 Items
Showing 1 - 20 of 189 Items
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Journal Article
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Research

Intravenous rehydration for severe acute malnutrition with gastroenteritis

Maitland K, Ouattara SM, Sainna H, Chara A, Ogundipe OF,  et al.
2025-06-13 • New England Journal of Medicine
2025-06-13 • New England Journal of Medicine

BACKGROUND

International recommendations advise against the use of intravenous rehydration therapy in children with severe acute malnutrition because of the con...

Journal Article
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Research

COVID-19, tuberculosis, and HIV triad: a prospective observational study in ambulatory patients in Kenya, Uganda, and South Africa

Huerga H, Gouillou M, Ohler L, Taremwa IM, Akinyi M,  et al.
2025-04-23 • PLOS Global Public Health
2025-04-23 • PLOS Global Public Health

People living with HIV (PLHIV) have an increased risk of tuberculosis (TB) and severe COVID-19. TB and COVI...

Journal Article
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Research

Low-dose yellow fever vaccine in adults in Africa

Kimathi D, Juan-Giner A, Bob NS, Orindi B, Namulwana ML,  et al.
2025-02-20 • New England Journal of Medicine
2025-02-20 • New England Journal of Medicine

BACKGROUND

Yellow fever vaccine is highly effective with a single dose, but vaccine supply is limited. The minimum dose requirements for seroconversion remain u...

Journal Article
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Research

Epidemiology and response to the COVID-19 pandemic in the Dadaab Refugee Camp Complex, Kenya, March 2020–December 2022

Ope M, Musyoka R, Kosar A, Osman M, Hassan A,  et al.
2025-01-01 • Travel Medicine and Infectious Disease
2025-01-01 • Travel Medicine and Infectious Disease

INTRODUCTION

Refugee settings may increase the risk of SARS-CoV-2 infection and death, yet...

Journal Article
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Pre-Print

A comparison of acceptability of contraceptive vaginal rings, pills, and injectables among cisgender women in Kenya and Zimbabwe: protocol for a mixed-methods study

Polis CB, Obare FO, Bruce IV, Banda C, Haddad LB,  et al.
2024-12-20 • VeriXiv
2024-12-20 • VeriXiv

BACKGROUND

Expanding contraceptive options could better meet users’ diverse needs and preferences. Annovera® is a contraceptive vaginal ring that pro...

Journal Article
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Commentary

Disease-specific differences in pharmacokinetics of paromomycin and miltefosine between post-kala-azar dermal leishmaniasis and visceral leishmaniasis patients in eastern Africa

Chu WY, Verrest L, Younis BM, Musa AM, Mbui J,  et al.
2024-12-16 • Journal of Infectious Diseases
2024-12-16 • Journal of Infectious Diseases

Treatment regimens for post-kala-azar dermal leishmaniasis (PKDL) are usually extrapolated from those for visceral leishmaniasis (VL), but drug pharmacokinetics (PK) can differ due to...

Journal Article
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Research

‘I can change my life’: perceptions and experiences of people who use drugs engaging in medically assisted therapy in Kiambu County, Kenya

Burtscher D, Riitho W, Kariuki M, Thiong’o A, Ayuaya T,  et al.
2024-11-17 • Drugs: Education, Prevention and Policy
2024-11-17 • Drugs: Education, Prevention and Policy

INTRODUCTION

The Médecins Sans Frontières (MSF) Kiambu People Who Use Drugs (PWUD) project, which started in September 2019, had enrolled 590 PWUD in its Medica...

Journal Article
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Research

Changes over time in the proportion of advanced HIV disease in two high HIV prevalence settings in Ndhiwa (Kenya) and Eshowe (South Africa)

Chihana M, Conan N, Ohler L, Huerga H, Wanjala S,  et al.
2024-06-17 • Journal of the International Association of Providers of AIDS Care
2024-06-17 • Journal of the International Association of Providers of AIDS Care
BACKGROUND
The burden of advanced HIV disease remains a significant concern in sub-Saharan Africa. In 2015, the World Health Organization released recommendations to treat all people...
Journal Article
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Research

Determinants of neonatal seizure among neonates admitted to neonatal intensive care units in the Awi Zone hospitals, 2023: A multi-center unmatched case control study

Alene T, Tsega TD, Terefe TF, Dessalegn N, Alem ZA,  et al.
2024-06-01 • Heliyon
2024-06-01 • Heliyon
BACKGROUND
Neonatal seizure is a common medical emergency that signals severe insult to the neonatal brain. It is a major risk factor for neonatal morbidity and mortality. It has a w...
Journal Article
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Commentary

Accumulating evidence on the long-term immunogenicity of fractional dosing for yellow fever vaccines

Juan-Giner A, Warimwe GM
2024-06-01 • Lancet Infectious Diseases
2024-06-01 • Lancet Infectious Diseases
Conference Material
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Poster

Innovative tele-mentoring programming in East Africa: Ongoing multi-year Project ECHO to increase access to palliative care in remote humanitarian settings across the region

Das E, Doherty M, Richardson K, Nafula E, Ali Z
2024-05-03 • MSF Paediatric Days 2024
2024-05-03 • MSF Paediatric Days 2024
Conference Material
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Poster

A case report of a child with acute abdomen who benefited from point-of-care ultrasound to confirm urgent surgical diagnosis in Homa Bay Hospital, Kenya

Phillip E, Adede J, Onduto S, Ochola C, Simba R,  et al.
2024-05-03 • MSF Paediatric Days 2024
2024-05-03 • MSF Paediatric Days 2024
Conference Material
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Poster

Optimizing nutrient supplementation among pregnant and reproductive age women in Kenya (VIRUTUBISHO)

Talbert A, Mwangome M, Berkley JA
2024-05-03 • MSF Paediatric Days 2024
2024-05-03 • MSF Paediatric Days 2024
Journal Article
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Research

Population pharmacokinetics of pediatric lopinavir/ritonavir oral pellets in children living with HIV in Africa

Chupradit S, Wamalwa DC, Maleche‐Obimbo E, Kekitiinwa AR, Mwanga‐Amumpaire J,  et al.
2024-05-01 • Clinical Pharmacology & Therapeutics
2024-05-01 • Clinical Pharmacology & Therapeutics
Antiretroviral therapy for children living with HIV (CLHIV) under 3 years of age commonly includes lopinavir/ritonavir (LPV/r). However, the original liquid LPV/r formulation has taste a...
Journal Article
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Review

Carriage of third-generation cephalosporin-resistant and carbapenem-resistant Enterobacterales among children in sub-Saharan Africa: a systematic review and meta-analysis

Ruef M, Emonet S, Merglen A, Dewez JE, Obama BM,  et al.
2024-03-11 • eClinicalMedicine
2024-03-11 • eClinicalMedicine
BACKGROUND
The increasing resistance of Enterobacterales to third-generation cephalosporins and carbapenems in sub-Saharan Africa (SSA) is a major public health concern. We did a sys...
Journal Article
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Review

Antimicrobial resistance in Enterobacterales infections among children in sub-Saharan Africa: a systematic review and meta-analysis

Kowalski M, Minka Obama B, Catho G, Dewez JE, Merglen A,  et al.
2024-03-08 • eClinicalMedicine
2024-03-08 • eClinicalMedicine
BACKGROUND
The burden of antimicrobial resistance (AMR) has been estimated to be the highest in sub-Saharan Africa (SSA). The current study estimated the proportion of drug-resistant...
Journal Article
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Research

Adolescents and young adults are the most undiagnosed of HIV and virally unsuppressed in Eastern and Southern Africa: Pooled analyses from five population-based surveys

Huerga H, Farhat JB, Maman D, Conan N, Van Cutsem G,  et al.
2023-12-22 • PLOS Global Public Health
2023-12-22 • PLOS Global Public Health
Age and gender disparities within the HIV cascade of care are critical to focus interventions efficiently. We assessed gender-age groups at the highest probability of unfavorable outcome...
Journal Article
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Protocol

Haematological dynamics following treatment of visceral leishmaniasis: a protocol for systematic review and individual participant data (IPD) meta-analysis

Munir A, Dahal P, Kumar R, Singh-Phulgenda S, Siddiqui NA,  et al.
2023-12-14 • BMJ Open
2023-12-14 • BMJ Open
INTRODUCTION
Visceral leishmaniasis (VL) is a parasitic disease with an estimated 30,000 new cases occurring annually. Despite anaemia being a common haematological manifestation of ...
Journal Article
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Research

How age and sex affect treatment outcomes for children with severe malnutrition: A multi-country secondary data analysis

Thurstans S, Opondo C, Bailey J, Stobaugh H, Loddo F,  et al.
2023-12-04 • Maternal and Child Nutrition
2023-12-04 • Maternal and Child Nutrition
Age and sex influence the risk of childhood wasting. We aimed to determine if wasting treatment outcomes differ by age and sex in children under 5 years, enroled in therapeutic and suppl...
Journal Article
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Research

Experiences and perceptions of urine sampling for tuberculosis testing among HIV patients: a multisite qualitative descriptive study

Lissouba P, Rücker SCM, Otieno LA, Akatukwasa C, Xulu S,  et al.
2023-11-30 • BMJ Open
2023-11-30 • BMJ Open
OBJECTIVES
Evidence on the acceptability of urine-based assays for tuberculosis (TB) diagnosis among patients remains limited. We sought to describe patients’ experiences and percept...