Search Results | MSF Science Portal

Journal Article

|

Research

du Cros PAK, Greig J, Cross GB, Cousins C, Berry C, et al.

2023-12-01 • International Journal of Tuberculosis and Lung Disease

BACKGROUND
The value, speed of completion and robustness of the evidence generated by TB treatment trials could be improved by implementing standards for best practice.

METH...

Journal Article

|

Research

Rekart ML, Aung A, Cullip T, Mulanda WK, Mun L, et al.

2023-10-01 • International Journal of Tuberculosis and Lung Disease

BACKGROUND
Tajikistan has a high burden of rifampicin-resistant TB (RR-TB), with 2,700 new cases estimated for 2021 (28/100,000 population). TB is spread among household members thro...

Journal Article

|

Research

Chiang SS, Graham SM, Schaaf HS, Marais BJ, Sant’Anna CC, et al.

2023-08-01 • International Journal of Tuberculosis and Lung Disease

BACKGROUND
These clinical standards aim to provide guidance for diagnosis, treatment, and management of drug-susceptible TB in children and adolescents.

METHODS
Fifty-tw...

Journal Article

|

Letter

Vengurlekar D, Walker C, Mahajan R, Dalal A, Chavan VV, et al.

2023-07-01 • International Journal of Tuberculosis and Lung Disease

Journal Article

|

Research

Rich ML, Khan UT, Zeng C, LaHood AN, Franke MF, et al.

2023-06-01 • International Journal of Tuberculosis and Lung Disease

BACKGROUND
Evidence of the effectiveness of the WHO-recommended design of longer individualized regimens for multidrug- or rifampicin-resistant TB (MDR/RR-TB) is limited.

OB...

Journal Article

|

Research

Moe S, Rekart ML, Hernandez D, Sholpan A, Ismailov A, et al.

2023-05-01 • International Journal of Tuberculosis and Lung Disease

BACKGROUND:
Bedaquiline (BDQ) is widely used in the treatment of rifampicin-resistant TB (RR-TB). However, resistance to BDQ is now emerging. There are no standardised regimens for ...

Journal Article

|

Letter

Campbell JR, Chan ED, Anderson LF, Bonnet M, Brode SK, et al.

2023-04-01 • International Journal of Tuberculosis and Lung Disease

Journal Article

|

Research

Zeng C, Mitnick CD, Hewison CCH, Bastard M, Khan PY, et al.

2023-01-01 • International Journal of Tuberculosis and Lung Disease

BACKGROUND
The WHO provides standardized outcome definitions for rifampicin-resistant (RR) and multidrug-resistant (MDR) TB. However, operationalizing these definitions can be challe...

Journal Article

|

Research

Mansoor H, Hirani N, Chavan VV, Das M, Sharma J, et al.

2023-01-01 • International Journal of Tuberculosis and Lung Disease

BACKGROUND
In high TB burden countries, access to drug susceptibility testing is a major bottleneck. Targeted next-generation sequencing (tNGS) is a promising technology for rapid re...

Journal Article

|

Letter

Memani B, Furin J, Cox HS, Reuter A

2022-12-01 • International Journal of Tuberculosis and Lung Disease

Journal Article

|

Letter

Furin J, Reuter A, Eyde L, Cox HS

2022-11-01 • International Journal of Tuberculosis and Lung Disease

Journal Article

|

Research

Mangochi P, Bossard C, Catacutan C, Van Laeken D, Kwitonda C, et al.

2022-10-01 • International Journal of Tuberculosis and Lung Disease

BACKGROUND
Incarcerated individuals, especially in high HIV and TB burden settings, are at increased risk of latent TB infection and/or TB disease. We implemented a comprehensive HIV...

Journal Article

|

Letter

Tyeku N, Apolisi I, Daniels J, Beko B, Memani B, et al.

2022-10-01 • International Journal of Tuberculosis and Lung Disease

Journal Article

|

Letter

Rekart ML, Morshed T, Mulanda WK, Klieascikova J, Sitali N, et al.

2022-08-01 • International Journal of Tuberculosis and Lung Disease

Journal Article

|

Research

Snyman L, Venables E, Trivino Duran L, Mohr E, Azevedo VD, et al.

2018-09-01 • International Journal of Tuberculosis and Lung Disease

SETTING
Early interventions for patients who interrupt their treatment for drug-resistant tuberculosis (DR-TB) are rarely reported and assessed. A novel, patient-centred intervention...

Journal Article

|

Research

Huerga H, Bastard M, Kamene M, Wanjala S, Arnold A, et al.

2017-03-01 • International Journal of Tuberculosis and Lung Disease

SETTING
In March 2006, the first multidrug-resistant tuberculosis (MDR-TB) treatment programme was implemented in Kenya.

OBJECTIVE
To describe patients' treatment outcom...

Journal Article

|

Research

Cox V, De Azevedo V, Stinson K, Wilkinson LS, Rangaka MX, et al.

2015-11-01 • International Journal of Tuberculosis and Lung Disease

BACKGROUND
The World Health Organization recommends tuberculin skin tests (TSTs) where feasible to identify individuals most likely to benefit from isoniazid preventive therapy (IPT)...

Journal Article

|

Research

Sinanovic E, Ramma L, Vassall A, Azevedo VD, Wilkinson LS, et al.

2015-02-01 • International Journal of Tuberculosis and Lung Disease

SETTING
The cost of multidrug-resistant tuberculosis (MDR-TB) treatment is a major barrier to treatment scale-up in South Africa.

OBJECTIVE
To estimate and compare the c...

Journal Article

|

Research

Bonnet MMB, Sizaire V, Kebede YYK, Janin A, Doshetov D, et al.

2005-10-01 • International Journal of Tuberculosis and Lung Disease

SETTING: After the collapse of the Soviet Union, countries in the region faced a dramatic increase in tuberculosis cases and the emergence of drug resistance. OBJECTIVE: To discuss the r...

Journal Article

|

Research

Bonnet MMB, Ramsay AR, Gagnidze L, Githui W, Guerin PJ, et al.

2007-09-01 • International Journal of Tuberculosis and Lung Disease

SETTING: Urban health clinic, Nairobi. OBJECTIVE: To evaluate the impact on tuberculosis (TB) case detection and laboratory workload of reducing the number of sputum smears examined and ...

Science Portal

Standards for clinical trials for treating TB

Household drug-resistant TB contact tracing in Tajikistan

Clinical standards for drug-susceptible TB in children and adolescents

Linezolid resistance in patients with drug-resistant TB

Outcomes of WHO-conforming, longer, all-oral multidrug-resistant TB regimens and analysis implications

Primary bedaquiline resistance in Karakalpakstan, Uzbekistan

Association of smoking and alcohol use with rifampin-resistant TB treatment outcomes

Concordance of three approaches for operationalizing outcome definitions for multidrug-resistant TB

Clinical utility of target-based next-generation sequencing for drug-resistant TB

A very sneaky bug: perspectives of front-line clinicians on whole-genome sequencing for drug-resistant TB

A test of infection should not be a “standard” for guiding TB preventive therapy in at-risk populations

TB screening, prevention and treatment cascade in a Malawi prison

Pediatric delamanid treatment for children with rifampicin-resistant TB

Family directly observed therapy for children with drug-resistant TB

'I didn't know so many people cared about me': support for patients who interrupt drug-resistant TB treatment

Outcomes from the first multidrug-resistant tuberculosis programme in Kenya

Diagnostic accuracy of tuberculin skin test self-reading by HIV patients in a low-resource setting

Impact of reduced hospitalisation on the cost of treatment for drug-resistant tuberculosis in South Africa

Does One Size Fit All? Drug Resistance and Standard Treatments: Results of Six Tuberculosis Programmes in Former Soviet Countries

Reducing the Number of Sputum Samples Examined and Thresholds for Positivity: An Opportunity to Optimise Smear Microscopy