Search Results | MSF Science Portal

Journal Article

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Research

Kosack CS, Nick S

2016-03-06 • Tropical Medicine and International Health

OBJECTIVE
To evaluate the diagnostic accuracy of the OraQuick HCV rapid antibody test from OraSure and the Multisure HCV antibody assay from MP Biomedicals.

METHODS
Five...

Journal Article

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Research

Kosack CS, de Kieviet W, Bayrak K, Milovic A, Page AL

2015-04-17 • PLOS One

Creatinine is a parameter that is required to monitor renal function and is important to follow in patients under treatment with potentially toxic renal drugs, such as the anti-HIV drug ...

Protocol

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Research Protocol

Kosack CS, Halton J, Greig J, Shanks L, Spijker S

2018-07-01

PRIMARY OBJECTIVE OF STUDY
• To demonstrate the extent of change in patient management through the availability of digital X-ray with teleradiology consultation.

SECOND...

Journal Article

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Research

Kosack CS, Page AL, Van Hulsteijn LT, Lentjes EG

2012-03-19 • PLOS One

Thyroid-stimulating hormone (TSH) promotes expression of thyroid hormones which are essential for metabolism, growth, and development. Second-line drugs to treat tuberculosis (TB) can ca...

Journal Article

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Research

Ardizzoni E, Fajardo E, Saranchuk P, Casenghi M, Page AL, et al.

2015-12-15 • PLOS One

BACKGROUND
The Xpert® MTB/RIF (Xpert) is an automated molecular test for simultaneous detection of tuberculosis (TB) and rifampicin resistance, recommended by the World Health Organi...

Journal Article

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Research

Fajardo E, Metcalf CJ, Piriou E, Gueguen M, Maman D, et al.

2015-06-25 • Bulletin of the World Health Organization

OBJECTIVE
To estimate the proportion of invalid results generated by a CD4+ T-lymphocyte analyser used by Médecins Sans Frontières (MSF) in field projects and identify factors associ...

Journal Article

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Research

Kosack CS, Page AL, Beelaert G, Benson TT, Savane A, et al.

2017-03-22 • Journal of the International AIDS Society

Although individual HIV rapid diagnostic tests (RDTs) show good performance in evaluations conducted by WHO, reports from several African countries highlight potentially significant perf...

Journal Article

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Commentary

Kosack CS, Page AL, Beelaert G, Benson TT, Savane A, et al.

2017-07-19 • Journal of the International AIDS Society

Protocol

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Research Protocol

Kosack CS

2014-06-01

Primary objective of this study:
To determine if the application of a tick-sheet after four hour training on its use and on CXR interpretation, improves the interpretation accuracy ...

Journal Article

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Review

Kosack CS

2012-03-16 • Clinical Chemistry and Laboratory Medicine

In medical humanitarian assistance, the diagnosis of diseases plays a crucial role. Laboratory investigations are one of the main diagnostic tools utilized in Médecins Sans Frontières' (...

Journal Article

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Research

Checchi F, Piola P, Kosack CS, Ardizzoni E, Klarkowski DB, et al.

2004-04-01 • Tropical Medicine and International Health

We report below an in vivo antimalarial efficacy study conducted in 2002 in Bundi Bugyo, a district of western Uganda housing a large displaced population. We tested sulfadoxine-pyrimeth...

Journal Article

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Research

Kosack CS, Nick S, Shanks L

2014-04-13 • Journal of Virological Methods

2% of the world's population lives with a hepatitis C virus (HCV) infection with highest rates in developing countries. The most common mode of transmission takes place via unsafe blood ...

Journal Article

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Research

Andronikou S, Lambert E, Halton J, Hilder L, Crumley I, et al.

2017-10-01 • Pediatric Radiology

Journal Article

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Review

Cunningham J, Jones SM, Gatton ML, Barnwell JW, Cheng Q, et al.

2019-12-02 • Malaria Journal

Malaria rapid diagnostic tests (RDTs) emerged in the early 1990s into largely unregulated markets, and uncertain field performance was a major concern for the acceptance of tests for mal...

Journal Article

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Research

Coulborn RM, Panunzi I, Spijker S, Brant WE, Trivino Duran L, et al.

2012-06-21 • Bulletin of the World Health Organization

Malawi has one of the world's highest rates of human immunodeficiency virus (HIV) infection (10.6%), and southern Malawi, where Thyolo district is located, bears the highest burden in th...

Journal Article

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Research

Kosack CS, Shanks L, Beelaert G, Benson TT, Savane A, et al.

2017-07-26 • Journal of Clinical Microbiology

Our objective was to evaluate the performance of HIV testing algorithms based on WHO recommendations, using data from specimens collected at six HIV testing and counselling sites in sub-...

Protocol

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Research Protocol

Kosack CS, Page AL, Shanks L, Chaillet P, Beelaert G, et al.

2018-07-01

Objectives
3.1 Primary objective
 To evaluate the overall and site-specific performance of the diagnostic algorithm performed at 6
MSF African program sites (i.e. using R...

Journal Article

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Research

Kosack CS, Spijker S, Halton J, Bonnet MMB, Nicholas S, et al.

2017-02-21 • Clinical Radiology

To assess the impact of introducing a chest radiograph reading and recording system (CRRS) with a short training session, on the accuracy and inter-reader variability of tuberculosis (TB...

Protocol

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Research Protocol

Kosack CS, Mesic A, Spijker S, Bonnet MMB, Joekes E

2018-07-01

Study objective
3.1 Primary objective
To determine if the application of a tick-sheet after four hour training on its use and on CXR
interpretation, improves the interpret...

Protocol

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Research Protocol

Kosack CS, Page AL, Moriyon I, Zuniga A, Conde R, et al.

2018-07-01

3. Objectives
3.1 Primary objective
To estimate the diagnostic accuracy (sensitivity, specificity, positive and negative predicative values and likelihood ratios) of the modifi...

Science Portal

Evaluation of two rapid screening assays for detecting hepatitis C antibodies in resource-constrained settings

Evaluation of the Nova StatSensor® XpressTM Creatinine Point-Of-Care Handheld Analyzer

The impact of digital X-ray with teleradiology on case management in Mweso, Democratic Republic of Congo

TSH-CHECK-1 test: diagnostic accuracy and potential application to initiating treatment for hypothyroidism in patients on anti-tuberculosis drugs

Implementing the Xpert MTB/RIF diagnostic test for tuberculosis and rifampicin resistance: outcomes and lessons learned in 18 countries

Errors generated by a point-of-care CD4+ T-lymphocyte analyser: a retrospective observational study in nine countries

Towards More Accurate HIV Testing in Sub-Saharan Africa: a Multi-Site Evaluation of HIV RDTs and Risk Factors For False Positives

Response to Comment on "Alert, but not Alarmed" - A Comment on "Towards More Accurate HIV Testing in Sub-Saharan Africa: A Multi-Site Evaluation of HIV RDTs and Risk Factors for False Positives (Kosack et al. 2017)"

Research Protocol - The Impact of a Tick-Sheet in Improving Interpretation Accuracy of Chest Radiographs by Non-Specialists in an HIV positive cohort

Experience of Médecins Sans Frontières in laboratory medicine in resource-limited settings

Antimalarial efficacy of sulfadoxine-pyrimethamine, amodiaquine and a combination of chloroquine plus sulfadoxine-pyrimethamine in Bundi Bugyo, western Uganda

Diagnostic accuracy evaluation of the ImmunoFlow HCV rapid immunochromatographic test for the detection of hepatitis C antibodies

Guidelines for the use of chest radiographs in community-acquired pneumonia in children and adolescents

A review of the WHO malaria rapid diagnostic test product testing programme (2008–2018): performance, procurement and policy

Feasibility of using teleradiology to improve tuberculosis screening and case management in a district hospital in Malawi

Designing HIV Testing Algorithms Based on 2015 WHO Guidelines Using Data from Six Sites in sub-Saharan Africa

Multi-site evaluation of HIV testing algorithms

Evaluation of a Chest Radiograph Reading and Recording System for Tuberculosis in a HIV-Positive Cohort

The Impact of a Tick-Sheet in Improving Interpretation Accuracy of Chest Radiographs by Non-Specialists in an HIV positive cohort

Determination of the most accurate diagnostic approach for the diagnosis of human brucellosis in Lankien, South-Sudan