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Showing 1 - 20 of 45 Items
Showing 1 - 20 of 45 Items
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Journal Article
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Research

Mycoplasma genitalium infection in Eswatini amid syndromic case management: Prevalence, coinfections, diagnostic challenges and treatment gaps

Kerschberger B, Lekelem S, Daka M, Ntshalintshali N, Mabhena E,  et al.
2025-04-17 • BMC Infectious Diseases
2025-04-17 • BMC Infectious Diseases

BACKGROUND

The global epidemic of Mycoplasma genitalium (MG) is marked by its widespread prevalence, varied resistance patterns, and significant impact on sexua...

Journal Article
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Research

‘I can change my life’: perceptions and experiences of people who use drugs engaging in medically assisted therapy in Kiambu County, Kenya

Burtscher D, Riitho W, Kariuki M, Thiong’o A, Ayuaya T,  et al.
2024-11-17 • Drugs: Education, Prevention and Policy
2024-11-17 • Drugs: Education, Prevention and Policy

INTRODUCTION

The Médecins Sans Frontières (MSF) Kiambu People Who Use Drugs (PWUD) project, which started in September 2019, had enrolled 590 PWUD in its Medica...

Journal Article
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Research

Understanding the role of video direct observed therapy for patients on an oral short-course regimen for multi-drug resistant tuberculosis: findings from a qualitative study in Eswatini

Mukooza E, Schausberger B, Mmema N, Dlamini V, Aung A,  et al.
2024-08-15 • BMC Infectious Diseases
2024-08-15 • BMC Infectious Diseases

BACKGROUND

Improving treatment success rates among multi drug-resistant tuberculosis (MDR-TB) patients is critical to reducing its incidence and mortality, but adherence poses a...

Journal Article
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Research

The introduction of video-enabled directly observed therapy (video-DOT) for patients with drug-resistant TB disease in Eswatini amid the COVID-19 pandemic – a retrospective cohort study

Kerschberger B, Daka M, Shongwe B, Dlamini T, Ngwenya S,  et al.
2024-06-03 • BMC Health Services Research
2024-06-03 • BMC Health Services Research
BACKGROUND
Video-enabled directly observed therapy (video-DOT) has been proposed as an additional option for treatment provision besides in-person DOT for patients with drug-resistan...
Conference Material
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Poster

Drivers of HIV pre-exposure prophylaxis choice among women in Eswatini

Mukooza E, Mmema N, Dlamini V, Dlamini SV, Mafomisa M,  et al.
2024-05-16 • MSF Scientific Day International 2024
2024-05-16 • MSF Scientific Day International 2024
Journal Article
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Letter

Is same-day antiretroviral therapy initiation beneficial? Methodological aspects when comparing observational and randomized studies

Schomaker M, Kerschberger B, Boulle A
2024-03-20 • Clinical Infectious Diseases
2024-03-20 • Clinical Infectious Diseases
Journal Article
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Research

“It is still very little; I cannot pass it on”: a qualitative study of experiences of diagnosis and treatment of acute HIV infection in Eswatini

Mukooza E, Schausberger B, Mmema N, Dlamini V, Aung A,  et al.
2024-03-01 • AIDS Care
2024-03-01 • AIDS Care
Acute and early HIV infection (AEHI) is rarely diagnosed in sub-Saharan Africa, despite its potential contribution to incidence reduction. This qualitative study in Eswatini explored the...
Journal Article
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Research

Sustained high fatality during TB therapy amid rapid decline in TB mortality at population level: A retrospective cohort and ecological analysis from Shiselweni, Eswatini

Kerschberger B, Vambe D, Schomaker M, Mabhena E, Daka M,  et al.
2024-03-01 • Tropical Medicine and International Health
2024-03-01 • Tropical Medicine and International Health
OBJECTIVES
Despite declining TB notifications in Southern Africa, TB‐related deaths remain high. We describe patient‐ and population‐level trends in TB‐related deaths in Eswatini ove...
Journal Article
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Pre-Print

The introduction of video-enabled directly observed therapy (video-DOT) for patients with drug-resistant TB disease in Eswatini amid the COVID-19 pandemic – a retrospective cohort study

Kerschberger B, Daka M, Shongwe B, Dlamini T, Ngwenya SM,  et al.
2023-08-09 • BMC Health Services Research
2023-08-09 • BMC Health Services Research
BACKGROUND
Video-enabled directly observed therapy (video-DOT) has been proposed as an additional option for treatment provision besides in-person DOT for patients with drug-resistan...
Journal Article
|
Letter

Response to “treatment outcomes after offering same-day Initiation of human immunodeficiency virus (HIV) treatment—how to interpret discrepancies between different studies”

Schomaker M, Kerschberger B, Boulle AM
2023-08-05 • Clinical Infectious Diseases
2023-08-05 • Clinical Infectious Diseases
Conference Material
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Slide Presentation

High burden of sexually transmitted infections and poor diagnostic performance of syndromic approaches within a decentralized HIV care setting in Eswatini

Kerschberger B, Mukooza E, Berto A, Ntshalintshali N, Mafomisa M,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023
Conference Material
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Abstract

High burden of sexually transmitted infections and poor diagnostic performance of syndromic approaches within a decentralised HIV care setting in Eswatini

Kerschberger B, Ntshalintshali N, Mafomisa M, Mabhena E, Daka M,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023
INTRODUCTION
Sexually transmitted infections (STI’s) are a public health threat. Syndromic approaches based on clinical symptoms have been suggested as having poor diagnostic perform...
Journal Article
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Research

"We have to learn to cooperate with each other": a qualitative study to explore integration of traditional healers into the provision of HIV self-testing and tuberculosis screening in Eswatini

Schausberger B, Mmema N, Dlamini V, Dube L, Aung A,  et al.
2021-12-06 • BMC Health Services Research
2021-12-06 • BMC Health Services Research
BACKGROUND
Traditional healing plays an important role in healthcare in Eswatini, and innovative collaborations with traditional healers may enable hard-to-reach men to access HIV an...
Journal Article
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Research

Time to initiation of antiretroviral therapy among patients with HIV-associated tuberculosis in Cape Town, South Africa

Lawn SD, Campbell L, Kaplan R, Boulle AM, Cornell M,  et al.
2011-06-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2011-06-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
We studied the time interval between starting tuberculosis treatment and commencing antiretroviral treatment (ART) in HIV-infected patients (n = 1433; median CD4 count 71 cells per micro...
Journal Article
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Research

Challenges and successes in the implementation of option B+ to prevent mother-to-child transmission of HIV in southern Swaziland

Etoori D, Kerschberger B, Staderini N, Ndlangamandla M, Nhlabatsi B,  et al.
2018-03-20 • BMC Public Health
2018-03-20 • BMC Public Health
Background
Universal antiretroviral therapy (ART) for all pregnant/ breastfeeding women living with Human Immunodeficiency Virus (HIV), known as Prevention of mother-to child transm...
Journal Article
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Research

MDR M. tuberculosis outbreak clone in Eswatini missed by Xpert has elevated bedaquiline resistance dated to the pre-treatment era

Beckert P, Sanchez-Padilla E, Merker M, Dreyer V, Kohl TA,  et al.
2020-11-25 • Genome Medicine
2020-11-25 • Genome Medicine
Background
Multidrug-resistant (MDR) Mycobacterium tuberculosis complex strains not detected by commercial molecular drug susceptibility testing (mDST) assays due to the RpoB I491F ...
Journal Article
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Research

Field suitability and diagnostic accuracy of the Biocentric open real-time PCR platform for dried blood spot-based HIV viral load quantification in Eswatini

Kerschberger B, Ntshalintshali N, Mpala Q, Diaz Uribe PA, Maphalala G,  et al.
2019-09-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2019-09-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
BACKGROUND
To assess the performance and suitability of dried blood spot (DBS) sampling using filter paper to collect blood for viral load (VL) quantification under routine condition...
Journal Article
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Research

Successes and challenges in optimizing the viral load cascade to improve antiretroviral therapy adherence and rationalize second-line switches in Swaziland

Etoori D, Ciglenecki I, Ndlangamandla M, Edwards CG, Jobanputra K,  et al.
2018-10-21 • Journal of the International AIDS Society
2018-10-21 • Journal of the International AIDS Society
As antiretroviral therapy (ART) is scaled up, more patients become eligible for routine viral load (VL) monitoring, the most important tool for monitoring ART efficacy. For HIV programme...
Journal Article
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Research

HIV programmatic outcomes following implementation of the 'Treat-All' policy in a public sector setting in Eswatini: a prospective cohort study

Kerschberger B, Schomaker M, Jobanputra K, Kabore SM, Teck R,  et al.
2020-03-03 • Journal of the International AIDS Society
2020-03-03 • Journal of the International AIDS Society
INTRODUCTION:
The Treat-All policy - antiretroviral therapy (ART) initiation irrespective of CD4 cell criteria - increases access to treatment. Many ART programmes, however, reporte...
Conference Material
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Abstract

Diagnostic performance of lateral flow point-of-care HIV-Combo testing for detection of acute HIV infection in Eswatini

Kerschberger B, Ntshalintshali N, Maphalala G, Aung A, Mamba C,  et al.
2021-05-19 • MSF Scientific Days International 2021: Research
2021-05-19 • MSF Scientific Days International 2021: Research
INTRODUCTION
Acute HIV infection (AHI) is rarely diagnosed in resource-limited settings. Barriers to diagnosis include the high costs of viral load (VL)-based diagnostic testing algo...