Guthmann JP, Pittet A, Lesage A, Imwong M, Lindegardh N, et al.
2008-01-01 • Tropical Medicine and International Health
2008-01-01 • Tropical Medicine and International Health
OBJECTIVE: To assess the efficacy of chloroquine in the treatment of Plasmodium vivax malaria in in Dawei District, southern Myanmar. METHODS: Enrolled patients at Sonsinphya clinic >6 m...
Guthmann JP, Kasparian S, Phetsouvanh R, Nathan N, Garcia MG, et al.
2002-09-01 • Annals of Tropical Medicine and Parasitology
2002-09-01 • Annals of Tropical Medicine and Parasitology
To assess the local efficacy of chloroquine for the treatment of acute, uncomplicated, Plasmodium falciparum malaria, children and adults from Sekong province (an area of Laos with a low...
2008-03-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2008-03-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
Inadequate evaluation of vaccine coverage after mass vaccination campaigns, such as used in national measles control programmes, can lead to inappropriate public health responses. Overes...
Guthmann JP, Cohuet S, Rigutto C, Fortes F, Saraiva N, et al.
2006-07-01 • American Journal of Tropical Medicine and Hygiene
2006-07-01 • American Journal of Tropical Medicine and Hygiene
In April 2004, 137 children 6-59 months of age with uncomplicated Plasmodium falciparum (Pf) malaria (Caala, Central Angola) were randomized to receive either artemether-lumefantrine (Co...
Biological samples collected in refugee camps during an outbreak of hepatitis E were used to compare the accuracy of hepatitis E virus RNA amplification by real-time reverse transcriptio...
BACKGROUND: Artesunate and amodiaquine (AS&AQ) is at present the world's second most widely used artemisinin-based combination therapy (ACT). It was necessary to evaluate the efficacy of...
Rolland E, Checchi F, Pinoges LLP, Balkan S, Guthmann JP, et al.
2006-04-01 • Tropical Medicine and International Health
2006-04-01 • Tropical Medicine and International Health
OBJECTIVE: To compare the cost-effectiveness of malaria treatment based on presumptive diagnosis with that of malaria treatment based on rapid diagnostic tests (RDTs). METHODS: We calcul...
Checchi F, Piola P, Kosack CS, Ardizzoni E, Klarkowski DB, et al.
2004-04-01 • Tropical Medicine and International Health
2004-04-01 • Tropical Medicine and International Health
We report below an in vivo antimalarial efficacy study conducted in 2002 in Bundi Bugyo, a district of western Uganda housing a large displaced population. We tested sulfadoxine-pyrimeth...
Stivanello E, Cavailler P, Cassano F, Omar SV, Kariuki D, et al.
2004-09-01 • Tropical Medicine and International Health
2004-09-01 • Tropical Medicine and International Health
To provide advice on the rational use of antimalarial drugs, Médecins Sans Frontières conducted a randomized, an open label efficacy study in Kajo Keji, an area of high transmission of m...
Nicand E, Armstrong GL, Enouf V, Guthmann JP, Guerin JP, et al.
2005-12-01 • Journal of Medical Virology
2005-12-01 • Journal of Medical Virology
The within-outbreak diversity of hepatitis E virus (HEV) was studied during the outbreak of hepatitis E that occurred in Sudan in 2004. Specimens were collected from internally displaced...
Spencer S, Grant AD, Piola P, Tukpo K, Okia M, et al.
2004-12-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2004-12-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
Malaria is a key health problem among displaced populations in malaria-endemic areas. Mass distribution of insecticide-treated bednets (ITN) to prevent malaria is often carried out in co...
Grandesso F, Hagerman A, Kamara S, Lam E, Checchi F, et al.
2006-07-01 • Tropical Medicine and International Health
2006-07-01 • Tropical Medicine and International Health
OBJECTIVE: In 2004, Sierra Leone adopted artesunate plus amodiaquine as first-line antimalarial treatment. We evaluated the efficacy of this combination in Kailahun, where a previous stu...
Imwong M, Snounou G, Pukrittayakamee S, Tanomsing N, Kim JH, et al.
2007-04-01 • Journal of Infectious Diseases
2007-04-01 • Journal of Infectious Diseases
BACKGROUND: Relapses originating from hypnozoites are characteristic of Plasmodium vivax infections. Thus, reappearance of parasitemia after treatment can result from relapse, recrudesce...
BACKGROUND: The six-dose regimen of artemether-lumefantrine is effective and is among combination therapies prioritised to replace antimalarials that no longer work in Africa. However, i...
Grais RF, Dubray C, Gerstl S, Guthmann JP, Djibo A, et al.
2007-01-01 • PLOS Medicine
2007-01-01 • PLOS Medicine
BACKGROUND: Despite the comprehensive World Health Organization (WHO)/United Nations Children's Fund (UNICEF) measles mortality-reduction strategy and the Measles Initiative, a partnersh...
Olliaro PL, Pinoges LLP, Checchi F, Vaillant M, Guthmann JP
2008-01-01 • Tropical Medicine and International Health
2008-01-01 • Tropical Medicine and International Health
OBJECTIVE: Parasites may recur asymptomatically after initial clearance by antimalarial treatment. Current guidelines recommend treatment only when patients develop symptoms or at the en...
Mugittu K, Priotto G, Guthmann JP, Kiguli J, Adjuik M, et al.
2007-02-01 • Tropical Medicine and International Health
2007-02-01 • Tropical Medicine and International Health
Polymerase chain reaction (PCR) genotyping of malaria parasites in drug efficacy trials helps differentiate reinfections from recrudescences. A combination therapy trial of one (n = 115)...
Guthmann JP, Pinoges LLP, Checchi F, Cousens S, Balkan S, et al.
2006-11-01 • Antimicrobial Agents and Chemotherapy
2006-11-01 • Antimicrobial Agents and Chemotherapy
The objectives of these analyses were to assess the feasibility of the latest WHO recommendations (28-day follow-up with PCR genotyping) for the assessment of antimalarial drug efficacy ...
2008-01-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2008-01-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
A study to assess the diagnostic capabilities of three parasite lactate dehydrogenase (pan-pLDH) tests, Vistapan), Carestart and Parabank), was conducted in Uganda. An HRP2 test, Parache...
