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Showing 1 - 20 of 73 Items
Showing 1 - 20 of 73 Items
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Journal Article
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Research

End of treatment and 12-month post-treatment outcomes in patients treated with all-oral regimens for rifampicin-resistant tuberculosis in Ukraine: a prospective cohort study

Fardhdiani V, Trush O, Lytvynenko N, Pylypchuk S, Terleeva Y,  et al.
2025-05-23 • PLOS Global Public Health
2025-05-23 • PLOS Global Public Health

The World Health Organization has called for operational research on all-oral shorter regimens for rifampin-resistant and multidrug-resistant forms of tuberculosis (RR/MDR-TB). We fol...

Journal Article
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Research

Enhancing tuberculosis (TB) case detection among hospitalized patients through lay health worker led screening: a before-and-after study in KwaZulu-Natal, South Africa

Bulti AB, Dumicho AY, Shigayeva A, Van Cutsem G, Steele SJ,  et al.
2025-04-23 • Scientific Reports
2025-04-23 • Scientific Reports

Tuberculosis (TB) among hospitalized patients is underdiagnosed. This study assessed systematic TB-screenin...

Journal Article
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Letter

Equitable access needed in clinical research

Dang G, Perrin C, Furin J
2025-03-28 • Science
2025-03-28 • Science
Journal Article
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Research

Characteristics of children and adolescents with multidrug-resistant and rifampicin-resistant tuberculosis and their association with treatment outcomes: a systematic review and individual participant data meta-analysis

Garcia-Prats AJ, Garcia-Cremades M, Cox V, Kredo T, Dunbar R,  et al.
2025-02-01 • Lancet Child and Adolescent Health
2025-02-01 • Lancet Child and Adolescent Health

BACKGROUND

There are few data on the treatment of children and adolescents with multidrug-resistant (MDR) or rifampicin-resistant (RR) tuberculosis, especially ...

Journal Article
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Pre-Print

Enhancing tuberculosis (TB) diagnosis among hospitalized patients in KwaZulu-Natal, South Africa: a before-and-after study of a lay health worker-driven intervention

Bulti AB, Dumicho AY, Shigayeva A, van Cutsem G, Steele SJ,  et al.
2024-03-08 • Scientific Reports
2024-03-08 • Scientific Reports
BACKGROUND
Tuberculosis (TB) among hospitalized patients is underdiagnosed. This study assessed systematic TB-screening, followed by an enhanced TB-diagnostic package for hospitaliz...
Journal Article
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Research

Standards for clinical trials for treating TB

du Cros PAK, Greig J, Cross GB, Cousins C, Berry C,  et al.
2023-12-01 • International Journal of Tuberculosis and Lung Disease
2023-12-01 • International Journal of Tuberculosis and Lung Disease
BACKGROUND
The value, speed of completion and robustness of the evidence generated by TB treatment trials could be improved by implementing standards for best practice.

METH...
Journal Article
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Research

Clinical standards for drug-susceptible TB in children and adolescents

Chiang SS, Graham SM, Schaaf HS, Marais BJ, Sant’Anna CC,  et al.
2023-08-01 • International Journal of Tuberculosis and Lung Disease
2023-08-01 • International Journal of Tuberculosis and Lung Disease
BACKGROUND
These clinical standards aim to provide guidance for diagnosis, treatment, and management of drug-susceptible TB in children and adolescents.

METHODS
Fifty-tw...
Journal Article
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Commentary

Diagnostics to support the scaling up of shorter, safer tuberculosis regimens

Branigan D, Denkinger CM, Furin J, Heitkamp P, Deborggraeve S,  et al.
2023-07-31 • Lancet Microbe
2023-07-31 • Lancet Microbe
Journal Article
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Commentary

Caring for adolescents and young adults with tuberculosis or at risk of tuberculosis: Consensus statement from an international expert panel

Chiang SS, Waterous PM, Atieno VF, Bernays S, Bondarenko Y,  et al.
2023-03-01 • Journal of Adolescent Health
2023-03-01 • Journal of Adolescent Health
Journal Article
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Research

Tuberculosis diagnosis and preventive monotherapy among children and adolescents exposed to rifampicin-resistant tuberculosis in the household

Apolisi I, Cox HS, Tyeku N, Daniels J, Mathee S,  et al.
2023-02-21 • Open Forum Infectious Diseases
2023-02-21 • Open Forum Infectious Diseases
BACKGROUND
Children and adolescents with household exposure to multidrug- or rifampicin-resistant tuberculosis (MDR/RR-TB) are at high risk of developing TB disease. Tuberculosis pre...
Journal Article
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Commentary

The 1/4/6x24 campaign to cure tuberculosis quickly

McKenna L, Frick M, Angami K, Dubula V, Furin J,  et al.
2023-01-01 • Nature Medicine
2023-01-01 • Nature Medicine
Journal Article
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Letter

A very sneaky bug: perspectives of front-line clinicians on whole-genome sequencing for drug-resistant TB

Memani B, Furin J, Cox HS, Reuter A
2022-12-01 • International Journal of Tuberculosis and Lung Disease
2022-12-01 • International Journal of Tuberculosis and Lung Disease
Journal Article
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Letter

A test of infection should not be a “standard” for guiding TB preventive therapy in at-risk populations

Furin J, Reuter A, Eyde L, Cox HS
2022-11-01 • International Journal of Tuberculosis and Lung Disease
2022-11-01 • International Journal of Tuberculosis and Lung Disease
Journal Article
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Research

TB screening, prevention and treatment cascade in a Malawi prison

Mangochi P, Bossard C, Catacutan C, Van Laeken D, Kwitonda C,  et al.
2022-10-01 • International Journal of Tuberculosis and Lung Disease
2022-10-01 • International Journal of Tuberculosis and Lung Disease
BACKGROUND
Incarcerated individuals, especially in high HIV and TB burden settings, are at increased risk of latent TB infection and/or TB disease. We implemented a comprehensive HIV...
Journal Article
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Letter

Pediatric delamanid treatment for children with rifampicin-resistant TB

Tyeku N, Apolisi I, Daniels J, Beko B, Memani B,  et al.
2022-10-01 • International Journal of Tuberculosis and Lung Disease
2022-10-01 • International Journal of Tuberculosis and Lung Disease
Journal Article
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Review

Demanding an end to tuberculosis: treatment of tuberculosis infection among persons living with and without HIV

Fargher J, Reuter A, Furin J
2019-01-01 • Current Opinion in HIV and AIDS
2019-01-01 • Current Opinion in HIV and AIDS
PURPOSE OF REVIEW
More than two billion people are infected with Mycobacterium tuberculosis and few of them are ever offered therapy in spite of such treatment being associated with ...
Journal Article
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Commentary

The need to accelerate access to new drugs for multidrug-resistant tuberculosis

Cox HS, Furin J, Mitnick CD, Daniels C, Cox V,  et al.
2015-07-01 • Bulletin of the World Health Organization
2015-07-01 • Bulletin of the World Health Organization
Approximately half a million people are thought to develop multidrug-resistant tuberculosis annually. Barely 20% of these people currently receive recommended treatment and only about 10...
Journal Article
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Research

The Epidemiology, Pathogenesis, Transmission, Diagnosis, and Management of Multidrug-Resistant, Extensively Drug-Resistant, and Incurable Tuberculosis

Dheda K, Gumbo T, Maartens G, Dooley KE, McNerney R,  et al.
2017-03-15 • Lancet Respiratory Medicine
2017-03-15 • Lancet Respiratory Medicine
Global tuberculosis incidence has declined marginally over the past decade, and tuberculosis remains out of control in several parts of the world including Africa and Asia. Although tube...
Journal Article
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Commentary

How COVID-19 could benefit tuberculosis and HIV services in South Africa

Keene CM, Mohr-Holland E, Cassidy T, Scott V, Nelson AM,  et al.
2020-09-01 • Lancet Respiratory Medicine
2020-09-01 • Lancet Respiratory Medicine
Journal Article
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Letter

A positive COVID-19 test is associated with high mortality in RR-TB-HIV patients

Mohr-Holland E, Daniels J, Douglas-Jones B, Mema N, Scott V,  et al.
2021-05-01 • International Journal of Tuberculosis and Lung Disease
2021-05-01 • International Journal of Tuberculosis and Lung Disease