BACKGROUND Over half of childhood tuberculosis (TB) remains undiagnosed yearly. WHO recommends Xpert-Ultra as a first paediatric diagnosis test, but microbiological confirmation rema...
Gutierrez R, Landa M, Sambou M, Bassane H, Dia N, et al.
2024-03-21 • Frontiers in Epidemiology
2024-03-21 • Frontiers in Epidemiology
BACKGROUND With growing use of parasitological tests to detect malaria and decreasing incidence of the disease in Africa; it becomes necessary to increase the understanding of causes...
Mahajan R, Nair MM, Saldanha AM, Harshana A, de Lima Pereira A, et al.
2021-07-01 • Journal of Vector Borne Diseases
2021-07-01 • Journal of Vector Borne Diseases
BACKGROUND AND OBJECTIVES There is limited evidence regarding the accuracy of dengue rapid diagnostic kits despite their extensive use in India. We evaluated the performance of four ...
Yun O, Lima MA, Ellman T, Chambi W, Castillo S, et al.
2009-07-07 • PLOS Neglected Tropical Diseases
2009-07-07 • PLOS Neglected Tropical Diseases
BACKGROUND: Chagas disease (American trypanosomiasis) is a zoonotic or anthropozoonotic disease caused by the parasite Trypanosoma cruzi. Predominantly affecting populations in poor...
Parrado R, Ramirez JC, de la Barra A, Alonso-Vega C, Juiz N, et al.
2018-12-03 • Antimicrobial Agents and Chemotherapy
2018-12-03 • Antimicrobial Agents and Chemotherapy
This work evaluated a serial blood sampling procedure to enhance the sensitivity of duplex real-time PCR (qPCR) for baseline detection and quantification of parasitic loads and post-trea...
Ramirez JC, Parrado R, Sulleiro E, de la Barra A, Rodriguez M, et al.
2017-11-27 • PLOS One
2017-11-27 • PLOS One
Real-Time PCR (qPCR) testing is recommended as both a diagnostic and outcome measurement of etiological treatment in clinical practice and clinical trials of Chagas disease (CD), but no ...
Priotto G, Chappuis F, Bastard M, Flevaud L, Etard JF
2012-06-05 • PLOS Neglected Tropical Diseases
2012-06-05 • PLOS Neglected Tropical Diseases
Human African trypanosomiasis is fatal without treatment. The long post-treatment follow-up (24 months) required to assess cure complicates patient management and is a major obstacle in ...
Ferreyra C, Yun O, Eisenberg N, Alonso E, Khamadi AS, et al.
2012-11-21 • PLOS One
2012-11-21 • PLOS One
In resource-limited settings where viral load (VL) monitoring is scarce or unavailable, clinicians must use immunological and clinical criteria to define HIV virological treatment failur...
Richard-Greenblatt M, Comar CE, Flevaud L, Berti M, Harris RM, et al.
2021-04-20 • Journal of Clinical Microbiology
2021-04-20 • Journal of Clinical Microbiology
Community-based healthcare clinics and hospital outreach services have the potential to expand coronavirus disease 2019 (COVID-19) diagnostics to rural areas. However, reduced specimen s...
Sinha PK, van Griensven J, Pandey K, Kumar N, Verma N, et al.
2011-10-01 • Clinical Infectious Diseases
2011-10-01 • Clinical Infectious Diseases
Reports on treatment outcomes of visceral leishmaniasis (VL)-human immunodeficiency virus (HIV) coinfection in India are lacking. To our knowledge, none have studied the efficacy of lipo...
Herrero M, Orfanos G, Argaw D, Mulugeta A, Aparicio P, et al.
2009-09-01 • American Journal of Tropical Medicine and Hygiene
2009-09-01 • American Journal of Tropical Medicine and Hygiene
In May 2005, visceral leishmaniasis (VL) was recognized for the first time in Libo Kemken, Ethiopia, a highland region where only few cases had been reported before. We analyzed records ...
Molina-de la Fuente I, Benito MJS, Flevaud L, Ousley J, Pasquale HA, et al.
2023-01-01 • Emerging Infectious Diseases
2023-01-01 • Emerging Infectious Diseases
Pfhrp2 and pfhrp3 gene deletions threaten the use of Plasmodium falciparum malaria rapid diagnostic tests globally. In South Sudan, deletion frequencies were 15.6% for pfhrp2, 20.0% for ...