Sweeney S, Laurence YV, Berry C, Singh MP, Dodd M, et al.
2025-02-01 • Lancet Global Health
2025-02-01 • Lancet Global Health
BACKGROUND
New 6-month rifampicin-resistant tuberculosis treatment regimens containing bedaquiline, pretomanid, and linezolid (BPaL) with or without moxifloxaci...
Motta I, Cusinato M, Ludman AJ, Lachenal N, Dodd M, et al.
2024-06-06 • Antimicrobial Agents and Chemotherapy
2024-06-06 • Antimicrobial Agents and Chemotherapy
Regimens for the treatment of rifampicin-resistant tuberculosis currently rely on the use of QT-prolonging agents. Using data from the randomized controlled trial, TB-PRACTECAL, we inves...
Hasan T, Medcalf E, Nyang'wa BT, Egizi E, Berry C, et al.
2024-03-20 • Clinical Infectious Diseases
2024-03-20 • Clinical Infectious Diseases
BACKGROUND Effectiveness, safety, tolerability, and adherence are critical considerations in shifting to shorter tuberculosis (TB) regimens. Novel 6-month oral regimens that include ...
Nyang'wa BT, Berry C, Kazounis E, Motta I, Parpieva N, et al.
2024-02-01 • Lancet Respiratory Medicine
2024-02-01 • Lancet Respiratory Medicine
BACKGROUND Around 500,000 people worldwide develop rifampicin-resistant tuberculosis each year. The proportion of successful treatment outcomes remains low and new treatments are nee...
Hasan T, Medcalf E, Nyang'wa BT, Egizi E, Berry C, et al.
2023-10-24 • Clinical Infectious Diseases
2023-10-24 • Clinical Infectious Diseases
BACKGROUND Effectiveness, safety, tolerability and adherence are critical considerations in shifting to shorter tuberculosis (TB) regimens. Novel six-month oral regimens that include...
2022-06-07 • MSF Scientific Days International 2022
Nyang'wa BT, Berry C, Kazounis E, Motta I, Parpieva N, et al.
2022-12-22 • New England Journal of Medicine
2022-12-22 • New England Journal of Medicine
BACKGROUND In patients with rifampin-resistant tuberculosis, all-oral treatment regimens that are more effective, shorter, and have a more acceptable side-effect profile than current...
Berry C, Motta I, Kazounis E, Fielding K, Dodd M, et al.
2022-05-11 • MSF Scientific Days International 2022
2022-05-11 • MSF Scientific Days International 2022
INTRODUCTION Rifamipcin-resistant tuberculosis (RR-TB) affects around 465,000 people each year globally. Current treatment is of 9-20 months’ duration; is toxic and poorly efficaciou...
Sweeney S, Berry C, Kazounis E, Motta I, Vassall A, et al.
2022-12-07 • PLOS Global Public Health
2022-12-07 • PLOS Global Public Health
Current options for treating tuberculosis (TB) that is resistant to rifampicin (RR-TB) are few, and regimens are often long and poorly tolerated. Following recent evidence from the TB-PR...
Sweeney S, Berry C, Kazounis E, Motta I, Vassall A, et al.
2022-11-10 • medRxiv
2022-11-10 • medRxiv
INTRODUCTION Current options for treating tuberculosis (TB) that is resistant to rifampicin (RR-TB) are few, and regimens are often long and poorly tolerated. Following recent eviden...