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Copyright © Médecins Sans Frontières
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Showing 1 - 12 of 12 Items
Showing 1 - 12 of 12 Items
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Journal Article
|
Research

The introduction of video-enabled directly observed therapy (video-DOT) for patients with drug-resistant TB disease in Eswatini amid the COVID-19 pandemic – a retrospective cohort study

Kerschberger B, Daka M, Shongwe B, Dlamini T, Ngwenya S,  et al.
2024-06-03 • BMC Health Services Research
2024-06-03 • BMC Health Services Research
BACKGROUND
Video-enabled directly observed therapy (video-DOT) has been proposed as an additional option for treatment provision besides in-person DOT for patients with drug-resistan...
Journal Article
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Research

Sustained high fatality during TB therapy amid rapid decline in TB mortality at population level: A retrospective cohort and ecological analysis from Shiselweni, Eswatini

Kerschberger B, Vambe D, Schomaker M, Mabhena E, Daka M,  et al.
2024-03-01 • Tropical Medicine and International Health
2024-03-01 • Tropical Medicine and International Health
OBJECTIVES
Despite declining TB notifications in Southern Africa, TB‐related deaths remain high. We describe patient‐ and population‐level trends in TB‐related deaths in Eswatini ove...
Journal Article
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Pre-Print

The introduction of video-enabled directly observed therapy (video-DOT) for patients with drug-resistant TB disease in Eswatini amid the COVID-19 pandemic – a retrospective cohort study

Kerschberger B, Daka M, Shongwe B, Dlamini T, Ngwenya SM,  et al.
2023-08-09 • BMC Health Services Research
2023-08-09 • BMC Health Services Research
BACKGROUND
Video-enabled directly observed therapy (video-DOT) has been proposed as an additional option for treatment provision besides in-person DOT for patients with drug-resistan...
Journal Article
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Letter

Revised definitions of multidrug-resistant tuberculosis treatment outcomes: closer to the reality?

Bastard M, Bonnet MMB, du Cros PAK, Khamraev AK, Hayrapetyan A,  et al.
2015-02-01 • American Journal of Respiratory and Critical Care Medicine
2015-02-01 • American Journal of Respiratory and Critical Care Medicine
Journal Article
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Research

High prevalence of multidrug-resistant tuberculosis, Swaziland, 2009-2010

Sanchez-Padilla E, Dlamini T, Ascorra A, Rusch-Gerdes S, Tefera ZD,  et al.
2012-01-01 • Emerging Infectious Diseases
2012-01-01 • Emerging Infectious Diseases
In Africa, although emergence of multidrug-resistant (MDR) tuberculosis (TB) represents a serious threat in countries severely affected by the HIV epidemic, most countries lack drug-resi...
Journal Article
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Research

High mortality in tuberculosis patients despite HIV interventions in Swaziland

Mchunu G, van Griensven J, Hinderaker SG, Kizito W, Sikhondze W,  et al.
2016-06-21 • Public Health Action
2016-06-21 • Public Health Action
SETTING
All health facilities providing tuberculosis (TB) care in Swaziland.

OBJECTIVE
To describe the impact of human immunodeficiency virus (HIV) interventions on the ...
Journal Article
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Research

Outcomes of HIV-infected versus HIV-non-infected patients treated for drug-resistance tuberculosis: Multicenter cohort study

Bastard M, Sanchez-Padilla E, du Cros PAK, Khamraev AK, Parpieva N,  et al.
2018-03-08 • PLOS One
2018-03-08 • PLOS One
The emergence of resistance to anti-tuberculosis (DR-TB) drugs and the HIV epidemic represent a serious threat for reducing the global burden of TB. Although data on HIV-negative DR-TB t...
Journal Article
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Research

What is the best culture conversion prognostic marker for patients treated for multidrug-resistant tuberculosis?

Bastard M, Sanchez-Padilla E, Hayrapetyan A, Kimenye K, Khurkhumal S,  et al.
2019-10-01 • International Journal of Tuberculosis and Lung Disease
2019-10-01 • International Journal of Tuberculosis and Lung Disease
INTRODUCTION
Identification of good prognostic marker for tuberculosis (TB) treatment response is a necessary step on the path towards a surrogate marker to reduce TB trial duration....
Journal Article
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Research

Bedaquiline and delamanid result in low rates of unfavourable outcomes among TB patients in Eswatini

Vambe D, Kay AW, Furin J, Howard AA, Dlamini T,  et al.
2020-10-01 • International Journal of Tuberculosis and Lung Disease
2020-10-01 • International Journal of Tuberculosis and Lung Disease
SETTING: Since 2015, Eswatini has been scaling up bedaquiline (BDQ) and delamanid (DLM) based drug-resistant TB treatment regimens under programmatic conditions.

OBJECTIVE: Id...
Journal Article
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Research

Countrywide roll-out of Xpert® MTB/RIF in Swaziland: the first three years of implementation

Sikhondze W, Dlamini T, Khumalo D, Maphalala G, Dlamini SV,  et al.
2015-06-21 • Public Health Action
2015-06-21 • Public Health Action
SETTING
All 19 public health laboratories in Swaziland that had Xpert(®) MTB/RIF machines installed as part of a countrywide roll-out between June 2011 and June 2014.

OBJECT...
Journal Article
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Letter

Detection of drug-resistant tuberculosis by Xpert MTB/RIF in Swaziland

Sanchez-Padilla E, Merker M, Jochims F, Dlamini T, Kahn P,  et al.
2015-03-19 • New England Journal of Medicine
2015-03-19 • New England Journal of Medicine
Journal Article
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Short Report

Operational aspects of bedaquiline implementation in Swaziland: report from the field

Vambe D, Dlamini T, Furin J, Gracia-Edwards C, Keus K,  et al.
2017-09-21 • Public Health Action
2017-09-21 • Public Health Action