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Showing 1 - 20 of 42 Items
Showing 1 - 20 of 42 Items
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Journal Article
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Research

Mycoplasma genitalium infection in Eswatini amid syndromic case management: Prevalence, coinfections, diagnostic challenges and treatment gaps

Kerschberger B, Lekelem S, Daka M, Ntshalintshali N, Mabhena E,  et al.
2025-04-17 • BMC Infectious Diseases
2025-04-17 • BMC Infectious Diseases

BACKGROUND

The global epidemic of Mycoplasma genitalium (MG) is marked by its widespread prevalence, varied resistance patterns, and significant impact on sexua...

Journal Article
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Research

Initial evaluation of a new cervical screening strategy combining human papillomavirus genotyping and automated visual evaluation: the Human Papillomavirus–Automated Visual Evaluation Consortium

Befano B, Kalpathy-Cramer J, Egemen D, Inturrisi F, Jeronimo J,  et al.
2025-03-18 • Journal of the National Cancer Institute
2025-03-18 • Journal of the National Cancer Institute

The HPV-Automated Visual Evaluation (PAVE) Consortium is validating a cervical screening strategy enabling accurate cervical screening in resource-limited settings. A rapid, low-cost ...

Journal Article
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Research

Understanding the role of video direct observed therapy for patients on an oral short-course regimen for multi-drug resistant tuberculosis: findings from a qualitative study in Eswatini

Mukooza E, Schausberger B, Mmema N, Dlamini V, Aung A,  et al.
2024-08-15 • BMC Infectious Diseases
2024-08-15 • BMC Infectious Diseases

BACKGROUND

Improving treatment success rates among multi drug-resistant tuberculosis (MDR-TB) patients is critical to reducing its incidence and mortality, but adherence poses a...

Journal Article
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Research

The introduction of video-enabled directly observed therapy (video-DOT) for patients with drug-resistant TB disease in Eswatini amid the COVID-19 pandemic – a retrospective cohort study

Kerschberger B, Daka M, Shongwe B, Dlamini T, Ngwenya S,  et al.
2024-06-03 • BMC Health Services Research
2024-06-03 • BMC Health Services Research
BACKGROUND
Video-enabled directly observed therapy (video-DOT) has been proposed as an additional option for treatment provision besides in-person DOT for patients with drug-resistan...
Conference Material
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Poster

Drivers of HIV pre-exposure prophylaxis choice among women in Eswatini

Mukooza E, Mmema N, Dlamini V, Dlamini SV, Mafomisa M,  et al.
2024-05-16 • MSF Scientific Day International 2024
2024-05-16 • MSF Scientific Day International 2024
Journal Article
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Research

“It is still very little; I cannot pass it on”: a qualitative study of experiences of diagnosis and treatment of acute HIV infection in Eswatini

Mukooza E, Schausberger B, Mmema N, Dlamini V, Aung A,  et al.
2024-03-01 • AIDS Care
2024-03-01 • AIDS Care
Acute and early HIV infection (AEHI) is rarely diagnosed in sub-Saharan Africa, despite its potential contribution to incidence reduction. This qualitative study in Eswatini explored the...
Journal Article
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Research

Sustained high fatality during TB therapy amid rapid decline in TB mortality at population level: A retrospective cohort and ecological analysis from Shiselweni, Eswatini

Kerschberger B, Vambe D, Schomaker M, Mabhena E, Daka M,  et al.
2024-03-01 • Tropical Medicine and International Health
2024-03-01 • Tropical Medicine and International Health
OBJECTIVES
Despite declining TB notifications in Southern Africa, TB‐related deaths remain high. We describe patient‐ and population‐level trends in TB‐related deaths in Eswatini ove...
Journal Article
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Pre-Print

The introduction of video-enabled directly observed therapy (video-DOT) for patients with drug-resistant TB disease in Eswatini amid the COVID-19 pandemic – a retrospective cohort study

Kerschberger B, Daka M, Shongwe B, Dlamini T, Ngwenya SM,  et al.
2023-08-09 • BMC Health Services Research
2023-08-09 • BMC Health Services Research
BACKGROUND
Video-enabled directly observed therapy (video-DOT) has been proposed as an additional option for treatment provision besides in-person DOT for patients with drug-resistan...
Conference Material
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Video

High burden of sexually transmitted infections and poor diagnostic performance of syndromic approaches within a decentralised HIV care setting in Eswatini

Mukooza E
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023
Conference Material
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Slide Presentation

High burden of sexually transmitted infections and poor diagnostic performance of syndromic approaches within a decentralized HIV care setting in Eswatini

Kerschberger B, Mukooza E, Berto A, Ntshalintshali N, Mafomisa M,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023
Conference Material
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Abstract

High burden of sexually transmitted infections and poor diagnostic performance of syndromic approaches within a decentralised HIV care setting in Eswatini

Kerschberger B, Ntshalintshali N, Mafomisa M, Mabhena E, Daka M,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023
INTRODUCTION
Sexually transmitted infections (STI’s) are a public health threat. Syndromic approaches based on clinical symptoms have been suggested as having poor diagnostic perform...
Journal Article
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Letter

Revised definitions of multidrug-resistant tuberculosis treatment outcomes: closer to the reality?

Bastard M, Bonnet MMB, du Cros PAK, Khamraev AK, Hayrapetyan A,  et al.
2015-02-01 • American Journal of Respiratory and Critical Care Medicine
2015-02-01 • American Journal of Respiratory and Critical Care Medicine
Journal Article
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Research

"We have to learn to cooperate with each other": a qualitative study to explore integration of traditional healers into the provision of HIV self-testing and tuberculosis screening in Eswatini

Schausberger B, Mmema N, Dlamini V, Dube L, Aung A,  et al.
2021-12-06 • BMC Health Services Research
2021-12-06 • BMC Health Services Research
BACKGROUND
Traditional healing plays an important role in healthcare in Eswatini, and innovative collaborations with traditional healers may enable hard-to-reach men to access HIV an...
Journal Article
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Research

Field suitability and diagnostic accuracy of the Biocentric open real-time PCR platform for dried blood spot-based HIV viral load quantification in Eswatini

Kerschberger B, Ntshalintshali N, Mpala Q, Diaz Uribe PA, Maphalala G,  et al.
2019-09-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2019-09-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
BACKGROUND
To assess the performance and suitability of dried blood spot (DBS) sampling using filter paper to collect blood for viral load (VL) quantification under routine condition...
Journal Article
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Research

High mortality in tuberculosis patients despite HIV interventions in Swaziland

Mchunu G, van Griensven J, Hinderaker SG, Kizito W, Sikhondze W,  et al.
2016-06-21 • Public Health Action
2016-06-21 • Public Health Action
SETTING
All health facilities providing tuberculosis (TB) care in Swaziland.

OBJECTIVE
To describe the impact of human immunodeficiency virus (HIV) interventions on the ...
Conference Material
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Abstract

Diagnostic performance of lateral flow point-of-care HIV-Combo testing for detection of acute HIV infection in Eswatini

Kerschberger B, Ntshalintshali N, Maphalala G, Aung A, Mamba C,  et al.
2021-05-19 • MSF Scientific Days International 2021: Research
2021-05-19 • MSF Scientific Days International 2021: Research
INTRODUCTION
Acute HIV infection (AHI) is rarely diagnosed in resource-limited settings. Barriers to diagnosis include the high costs of viral load (VL)-based diagnostic testing algo...
Journal Article
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Research

PrEP reminds me that I am the one to take responsibility of my life: a qualitative study exploring experiences of and attitudes towards pre-exposure prophylaxis use by women in Eswatini

Bjertrup PJ, Mmema N, Dlamini V, Ciglenecki I, Mpala Q,  et al.
2021-04-14 • BMC Public Health
2021-04-14 • BMC Public Health
BACKGROUND
Pre-exposure-prophylaxis (PrEP) has been heralded for its potential to put women in control of preventing HIV infection, but uptake and continuation rates have been disapp...
Journal Article
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Research

Evaluating smartphone strategies for reliability, reproducibility, and quality of VIA for cervical cancer screening in the Shiselweni region of Eswatini: A cohort study

Asgary R, Staderini N, Mthethwa-Hleza S, Lopez Saavedra PA, Garcia Abrego L,  et al.
2020-11-19 • PLOS Medicine
2020-11-19 • PLOS Medicine
BACKGROUND
Cervical cancer is among the most common preventable cancers with the highest morbidity and mortality. The World Health Organization (WHO) recommends visual inspection of ...
Conference Material
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Abstract

Diagnosing and treating cases of acute HIV infection within a high HIV incidence setting: feasibility study, Eswatini

Aung A, Mamba C, Ntshalintshali N, Mpala Q, Mthethwa-Hleza S,  et al.
2020-05-26 • MSF Scientific Days International 2020: Research
2020-05-26 • MSF Scientific Days International 2020: Research
INTRODUCTION
Acute HIV infection (AHI) cannot be detected with routine point-of-care antibody tests and is rarely diagnosed in resource-limited settings. However, characteristics of ...
Conference Material
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Abstract

Video/Virtually Observed Therapy for patients with drug-resistant tuberculosis in Eswatini: a rapid response to COVID-19 lockdown measures

Aung A, Daka M, Tamrat A, Gwitima T, Chidhuro T,  et al.
2021-05-20 • MSF Scientific Days International 2021: Innovation
2021-05-20 • MSF Scientific Days International 2021: Innovation
WHAT CHALLENGE OR OPPORTUNITY DID YOU TRY TO ADDRESS? WERE EXISTING SOLUTIONS NOT AVAILABLE OR NOT GOOD ENOUGH?
The COVID-19 pandemic has prompted lockdown measures in many places, b...