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Prevalence and outcomes of antibiotic resistant infections at MSF projects | Collections | MSF Science Portal
Prevalence and outcomes of antibiotic resistant infections at MSF projects

Prevalence and outcomes of antibiotic resistant infections at MSF projects

Collection Content

Journal Article
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Research

Faecal carriage of extended-spectrum ß-lactamase-producing Escherichia coli in a remote region of Niger

Jacquier H, Assao B, Chau F, Guindo O, Condamine B,  et al.
2023-06-25 • Journal of Infection
2023-06-25 • Journal of Infection
OBJECTIVE
Whole genome sequencing (WGS) of extended-spectrum ß-lactamase-producing Escherichia coli (ESBL-E. coli) in developing countries is lacking. Here we describe the population...
Conference Material
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Abstract

Invasive bacterial infections in patients with advanced HIV disease in Kinshasa: prevalence, antibiotic resistance and treatment

Langendorf C
2023-06-08 • Epicentre Scientific Day Paris 2023
2023-06-08 • Epicentre Scientific Day Paris 2023
BACKGROUND
Patients with advanced HIV disease (AHD), defined as WHO clinical stage 3 or 4 and/or CD4<200, have a high risk of death. One common cause of death is invasive bacterial i...
Conference Material
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Poster

Post-traumatic Pseudomonas aeruginosa osteomyelitis patients admitted to MSF orthopaedic centers in Mosul, Iraq and Gaza, Palestine: a retrospective study

Qasim A, Qasim A, Aqel R, Walker C, Moussally K,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023
Conference Material
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Abstract

Treating post-trauma osteomyelitis cases in the conflict setting of Gaza: a retrospective cohort study

Aqel R
2022-06-01 • Epicentre Scientific Day Paris 2022
2022-06-01 • Epicentre Scientific Day Paris 2022
BACKGROUND
Post-traumatic osteomyelitis (PTO) is a serious consequence of orthopaedic trauma often complicated with multi-drug resistant (MDR) infections, a major health issue global...
Conference Material
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Abstract

The antibiotic resistance patterns shown in an acute trauma hospital in Aden, Yemen from 2018 to June 2021

Malaeb R, Nagwan Y
2022-06-01 • Epicentre Scientific Day Paris 2022
2022-06-01 • Epicentre Scientific Day Paris 2022
BACKGROUND
Antimicrobial resistance (AMR) is a global health problem and growing at an alarming rate, resulting in a rapid deterioration of the effectiveness of antibiotics. The midd...
Journal Article
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Research

The challenge of antibiotic resistance in post-war Mosul, Iraq: An analysis of 20 months microbiological samples from a tertiary orthopaedic care centre

M'Aiber S, Maamari K, Williams A, Albakry Z, Taher AQM,  et al.
2022-06-01 • Journal of Global Antimicrobial Resistance
2022-06-01 • Journal of Global Antimicrobial Resistance
BACKGROUND
Iraq has suffered unrest and conflicts in the past decades leaving behind a weakened healthcare system. In 2018, Médecins Sans Frontières (MSF) opened a tertiary orthopaed...
Journal Article
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Research

When first line treatment of neonatal infection is not enough: blood culture and resistance patterns in neonates requiring second line antibiotic therapy in Bangui, Central African Republic

Nebbioso A, Ogundipe OF, Repetto EC, Mekiedje C, Sanke-Waigana H,  et al.
2021-12-13 • BMC Pediatrics
2021-12-13 • BMC Pediatrics
BACKGROUND
Infectious diseases account for the third most common cause of neonatal deaths. Globally, antibiotic resistance (ABR) has been increasingly challenging neonatal sepsis tre...
Journal Article
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Research

Prevalence of MDR bacteria in an acute trauma hospital in Port-au-Prince, Haiti: a retrospective analysis from 2012 to 2018

Acma A, Williams A, Repetto EC, Cabral S, Sunyoto T,  et al.
2021-09-06 • JAC-Antimicrobial Resistance
2021-09-06 • JAC-Antimicrobial Resistance
BACKGROUND
Antibiotic resistance (ABR) is recognized as an increasing threat to global health. Haiti declared ABR an emerging public health threat in 2018, however, the current surve...
Journal Article
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Research

Post-traumatic osteomyelitis in Middle East war-wounded civilians: resistance to first-line antibiotics in selected bacteria over the decade 2006-2016

Fily F, Ronat JB, Malou N, Kanapathipillai R, Seguin C,  et al.
2019-01-31 • BMC Infectious Diseases
2019-01-31 • BMC Infectious Diseases
BACKGROUND
War-wounded civilians in Middle East countries are at risk of post-traumatic osteomyelitis (PTO). We aimed to describe and compare the bacterial etiology and proportion of...

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Diabetes care in humanitarian settings

Diabetes care in humanitarian settings
Diabetes affect hundreds of millions of people worldwide, a large majority of them living in low- and middle-income countries. Yet finding effective strategies, tools and policies for effectively managing this chronic illness—especially amid war, displacement or exclusion from care—is a neglected area of humanitarian medicine. Here we present a cross-section of work on this front by MSF and collaborators. Several studies assess the shift towards community-based, nurse-led models of care in rural settings. Others explore obstacles to diabetes care for war refugees living in camps in Jordan or Lebanon, highlighting how health programs can adapt to their needs. The demonstration that insulin retains potency for 30 days if cooled without refrigeration is opening doors to more patient self-management, as a case study in remote South Sudan shows. At the same time, MSF and others call for regulatory and financing policies that make diabetes medications and supplies cheaper, better adapted to humanitarian settings, and far more available to patients whose lives depend on them.
World Hepatitis Day 2024

World Hepatitis Day 2024

Viral hepatitis is a significant cause of disease and death globally. Yet powerful new medical tools to combat hepatitis C and E still reach only a tiny fraction of people who desperately need them, especially in low-resource and emergency settings.


To mark World Hepatitis Day (July 28th) we highlight recent MSF research on making these breakthrough products more widely accessible and simpler to use.


For hepatitis C, where groundbreaking antiviral drugs can cure nearly all patients, MSF is developing comprehensive, community-based models of care that offer rapid screening, diagnosis, and treatment under one roof. In some settings programs focus on the specific needs of highly vulnerable populations, such as people living in remote areas, forcibly displaced refugees, or those co-infected with HIV or TB or who inject drugs.


Turning to prevention, MSF is exploring ways to use the Hepatitis E vaccine more effectively in areas where poor sanitation and water quality regularly lead to outbreaks. Studies in a South Sudanese camp for internally displaced people are strengthening evidence for the vaccine’s feasibility, efficacy, safety and community acceptance, especially for pregnant women and their fetuses. Another report analyzes strategies for overcoming barriers to widespread vaccine adoption.

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MSF Scientific Days International 2023
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