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Prevalence and outcomes of antibiotic resistant infections at MSF projects | Collections | MSF Science Portal
Prevalence and outcomes of antibiotic resistant infections at MSF projects

Prevalence and outcomes of antibiotic resistant infections at MSF projects

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World Refugee Day 2022

World Refugee Day 2022

As we mark World Refugee Day (20 June 2022), over 100 million people globally are forcibly displaced from their home—the highest number ever recorded, according to the United Nations Refugee Agency. The health impacts of this displacement are dire: millions of people exposed to violence, infectious disease, and exclusion from health care during often-treacherous journeys or in detention centers and refugee camps.


Here we bring you a selection of MSF research aimed at better understanding and meeting the medical needs of populations along their migration route. Some studies describe the physical and psychological wounds our teams witness among specific populations—from unaccompanied minors to people detained under inhumane conditions in Libya or rescued from drowning after risking everything in perilous Mediterranean Sea crossings. Others assess ways to improve models of care for refugees with chronic diseases like hypertension and diabetes, or for tackling infectious diseases such as diphtheria and hepatitis E in overcrowded, unhygienic camps.

Mini-Lab—MSF's simplified bacteriology laboratory for low-resource settings

Mini-Lab—MSF's simplified bacteriology laboratory for low-res...
Resistance to antibiotics is a growing public health crisis, especially in countries with fragile health systems and in regions at war. One key limitation in most of these settings is a lack of clinical bacteriology laboratory capacity, which leaves medical providers without ways to accurately diagnose patient infections and to tailor antibiotic treatment accordingly. To help fill this critical gap, MSF and partners have developed the Mini-Lab—a small-scale, standalone lab that is easy to transport, set up and operate by staff after only a short training. Its six modules are stocked with everything needed to diagnose common bloodstream and urinary tract infections and to perform antibiotic sensitivity testing using methods adapted to extremely hot climates and remote settings. With Mini-Lab now being rolled out to selected MSF projects, here we highlight the background to its development and some of the research behind the bacteriological tests it incorporates.
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MSF Scientific Days International 2023
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Journal Article
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Research

Faecal carriage of extended-spectrum ß-lactamase-producing Escherichia coli in a remote region of Niger

Jacquier H, Assao B, Chau F, Guindo O, Condamine B,  et al.
2023-06-25 • Journal of Infection
2023-06-25 • Journal of Infection
OBJECTIVE
Whole genome sequencing (WGS) of extended-spectrum ß-lactamase-producing Escherichia coli (ESBL-E. coli) in developing countries is lacking. Here we describe the population...
Conference Material
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Abstract

Invasive bacterial infections in patients with advanced HIV disease in Kinshasa: prevalence, antibiotic resistance and treatment

Langendorf C
2023-06-08 • Epicentre Scientific Day Paris 2023
2023-06-08 • Epicentre Scientific Day Paris 2023
BACKGROUND
Patients with advanced HIV disease (AHD), defined as WHO clinical stage 3 or 4 and/or CD4<200, have a high risk of death. One common cause of death is invasive bacterial i...
Conference Material
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Poster

Post-traumatic Pseudomonas aeruginosa osteomyelitis patients admitted to MSF orthopaedic centers in Mosul, Iraq and Gaza, Palestine: a retrospective study

Qasim A, Qasim A, Aqel R, Walker C, Moussally K,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023
Conference Material
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Abstract

Treating post-trauma osteomyelitis cases in the conflict setting of Gaza: a retrospective cohort study

Aqel R
2022-06-01 • Epicentre Scientific Day Paris 2022
2022-06-01 • Epicentre Scientific Day Paris 2022
BACKGROUND
Post-traumatic osteomyelitis (PTO) is a serious consequence of orthopaedic trauma often complicated with multi-drug resistant (MDR) infections, a major health issue global...
Conference Material
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Abstract

The antibiotic resistance patterns shown in an acute trauma hospital in Aden, Yemen from 2018 to June 2021

Malaeb R, Nagwan Y
2022-06-01 • Epicentre Scientific Day Paris 2022
2022-06-01 • Epicentre Scientific Day Paris 2022
BACKGROUND
Antimicrobial resistance (AMR) is a global health problem and growing at an alarming rate, resulting in a rapid deterioration of the effectiveness of antibiotics. The midd...
Journal Article
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Research

The challenge of antibiotic resistance in post-war Mosul, Iraq: An analysis of 20 months microbiological samples from a tertiary orthopaedic care centre

M'Aiber S, Maamari K, Williams A, Albakry Z, Taher AQM,  et al.
2022-06-01 • Journal of Global Antimicrobial Resistance
2022-06-01 • Journal of Global Antimicrobial Resistance
BACKGROUND
Iraq has suffered unrest and conflicts in the past decades leaving behind a weakened healthcare system. In 2018, Médecins Sans Frontières (MSF) opened a tertiary orthopaed...
Journal Article
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Research

When first line treatment of neonatal infection is not enough: blood culture and resistance patterns in neonates requiring second line antibiotic therapy in Bangui, Central African Republic

Nebbioso A, Ogundipe OF, Repetto EC, Mekiedje C, Sanke-Waigana H,  et al.
2021-12-13 • BMC Pediatrics
2021-12-13 • BMC Pediatrics
BACKGROUND
Infectious diseases account for the third most common cause of neonatal deaths. Globally, antibiotic resistance (ABR) has been increasingly challenging neonatal sepsis tre...
Journal Article
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Research

Prevalence of MDR bacteria in an acute trauma hospital in Port-au-Prince, Haiti: a retrospective analysis from 2012 to 2018

Acma A, Williams A, Repetto EC, Cabral S, Sunyoto T,  et al.
2021-09-06 • JAC-Antimicrobial Resistance
2021-09-06 • JAC-Antimicrobial Resistance
BACKGROUND
Antibiotic resistance (ABR) is recognized as an increasing threat to global health. Haiti declared ABR an emerging public health threat in 2018, however, the current surve...
Journal Article
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Research

Post-traumatic osteomyelitis in Middle East war-wounded civilians: resistance to first-line antibiotics in selected bacteria over the decade 2006-2016

Fily F, Ronat JB, Malou N, Kanapathipillai R, Seguin C,  et al.
2019-01-31 • BMC Infectious Diseases
2019-01-31 • BMC Infectious Diseases
BACKGROUND
War-wounded civilians in Middle East countries are at risk of post-traumatic osteomyelitis (PTO). We aimed to describe and compare the bacterial etiology and proportion of...