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Combatting antimicrobial resistance | Collections | MSF Science Portal

Antimicrobial resistance is a growing public health crisis, especially in countries with fragile health systems, population displacement or ongoing conflict. In 2019 antibiotic-resistant bacteria directly caused an estimated 1.27 million deaths, and contributed to 4.95 million deaths, tolls that will continue to increase if no effective action is taken.


MSF’s approach to combatting antimicrobial resistance combines three pillars: infection prevention and control, microbiology and surveillance, and rational use of antibiotics via antibiotic stewardship. Several studies characterize patterns and prevalence of antibiotic resistance among MSF patients, from civilians wounded in Middle East conflicts to hospitalized neonates in Central African Republic and Haiti. New technologies developed by MSF and partners are expanding local capacity for rapid, accurate laboratory diagnosis of infections, so that clinicians can prescribe the right antibiotic for each patient. Other work assesses the practices and challenges related to optimizing rational antibiotic use within health facilities and communities.

If you're interested in learning more about MSF's work in antimicrobial resistance, view the full list of MSF's publications on the topic.

Collection Content

Journal Article
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Research

Antibiotic consumption in hospitals in humanitarian settings in Afghanistan, Bangladesh, Democratic Republic of Congo, Ethiopia and South Sudan

Skender K, Versace G, Lenglet AD, Clezy K
2024-08-15 • Antimicrobial Resistance and Infection Control
2024-08-15 • Antimicrobial Resistance and Infection Control

BACKGROUND

Antimicrobial resistance is of great global public health concern. In order to address the paucity of antibiotic consumption data and antimicrobial resistance surveil...

Conference Material
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Abstract

Antibiogo as an innovative solution to detect antimicrobial resistance: from an operational need to a CE-marked diagnostic test available for low-income and middle-income countries

Rapoud D, Cramer E, Al Asmar M, Sagara F, Ndiaye B,  et al.
2024-05-16 • MSF Scientific Day International 2024
2024-05-16 • MSF Scientific Day International 2024
INTRODUCTION
Antimicrobial resistance (AMR) is a major threat to public health and could cause 10 million deaths per year by 2050. Access to high-quality diagnostic tests is a key in...
Journal Article
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Review

Antimicrobial resistance in bacterial wound, skin, soft tissue and surgical site infections in Central, Eastern, Southern and Western Africa: A systematic review and meta-analysis

Monk EJM, Jones TPW, Bongomin F, Kibone W, Nsubuga Y,  et al.
2024-04-16 • PLOS Global Public Health
2024-04-16 • PLOS Global Public Health
Antimicrobial resistance (AMR) is a major global threat and AMR-attributable mortality is particularly high in Central, Eastern, Southern and Western Africa. The burden of clinically inf...
Journal Article
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Letter

Antimicrobial resistance in the ongoing Gaza war: a silent threat

Moussally K, Abu-Sittah G, Gomez FG, Fayad AA, Farra A
2023-11-09 • Lancet
2023-11-09 • Lancet
Journal Article
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Commentary

Antimicrobial stewardship in primary health care programs in humanitarian settings: the time to act is now

Truppa C, Alonso B, Clezy K, Deglise C, Dromer C,  et al.
2023-09-04 • Antimicrobial Resistance and Infection Control
2023-09-04 • Antimicrobial Resistance and Infection Control
Fragile and conflict-affected settings bear a disproportionate burden of antimicrobial resistance, due to the compounding effects of weak health policies, disrupted medical supply chains...
Journal Article
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Research

Practices and challenges related to antibiotic use in paediatric treatment in hospitals and health centres in Niger and Uganda: a mixed methods study

Mambula G, Nanjebe D, Munene A, Guindo O, Salifou A,  et al.
2023-07-11 • Antimicrobial Resistance and Infection Control
2023-07-11 • Antimicrobial Resistance and Infection Control
BACKGROUND
Antibiotic resistance is a significant public health problem and is responsible for high mortality in children and new-borns. Strengthening the rational use of antibiotics...
Journal Article
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Research

When first line treatment of neonatal infection is not enough: blood culture and resistance patterns in neonates requiring second line antibiotic therapy in Bangui, Central African Republic

Nebbioso A, Ogundipe OF, Repetto EC, Mekiedje C, Sanke-Waigana H,  et al.
2021-12-13 • BMC Pediatrics
2021-12-13 • BMC Pediatrics
BACKGROUND
Infectious diseases account for the third most common cause of neonatal deaths. Globally, antibiotic resistance (ABR) has been increasingly challenging neonatal sepsis tre...
Journal Article
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Review

The socioeconomic burden of antibiotic resistance in conflict-affected settings and refugee hosting countries: a systematic scoping review

Kobeissi L, Menassa M, Mousally K, Repetto EC, Soboh I,  et al.
2021-04-06 • Conflict and Health
2021-04-06 • Conflict and Health
BACKGROUND
Antibiotic resistance (ABR) is a major global threat. Armed and protracted conflicts act as multipliers of infection and ABR, thus leading to increased healthcare and soci...
Journal Article
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Commentary

The Mini-Lab: accessible clinical bacteriology for low-resource settings

Natale A, Ronat JB, Mazoyer A, Rochard A, Boillot B,  et al.
2020-06-01 • Lancet Microbe
2020-06-01 • Lancet Microbe

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MSF Paediatric Days 2024 abstracts
MSF Paediatric Days 2024 abstracts
On 3-4 May in Nairobi, Kenya, MSF gathered staff from our projects with experts from academia, clinical practice and the non-governmental sector to consider key issues in humanitarian paediatrics. These included: Vaccination and vaccine-preventable diseases: Amid post-Covid-19 global setbacks in child vaccination coverage, sessions spotlighted recent increases in vaccine-preventable disease outbreaks, potential new vaccination strategies and emergency responses, and MSF’s role in vaccine advocacy and catch-up campaigns. Nutrition: Talks covered the nexus of nutrition with other key conference topics, the latest malnutrition guidance and tools, and MSF’s priorities in nutritional care. Paediatric HIV: With half of all HIV-positive children globally not receiving antiretroviral therapy, presenters reviewed the latest paediatric testing/treatment recommendations and discussed barriers and potential solutions to implementation, nutritional challenges in children with HIV, and systems strengthening for preventing and monitoring paediatric HIV. Click below to read the abstracts. And stay tuned for more conference content, coming soon.
MSF logo
World TB Day 2022—Progress on tools and care models amid glob...
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MSF Scientific Days Latin America 2024
MSF Scientific Days Latin America 2024

MSF Scientific Days in Latin America 2024 focused on two thematic areas:

Climate Emergency in the Americas: What Are We Seeing as a Medical Humanitarian Organization and How Are We Responding?

  • MSF has long responded to health crises aggravated by the climate emergency —such as disease outbreaks, food insecurity, and displacement—and these events are intensifying in severity and frequency. This session presented examples of how MSF is adapting to address climate-related emergencies in the region, and explored strategies for future humanitarian action.

Mental Health and Psychosocial Support Interventions in Violence, Migration, and Indigenous Health Projects

  • This session explored the complexities of providing mental health and psychosocial support (MHPSS) in some of the region’s most challenging settings. It focused on interventions in areas affected by violence, the mental health impact on migrants, and the unique needs of indigenous populations. The discussion highlighted innovative strategies, culturally sensitive approaches, and the importance of integrating MHPSS into healthcare projects in these complex settings.
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Combatting antimicrobial resistance

Combatting antimicrobial resistance