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TB Research Dissemination Workshop 2022 | Collections | MSF Science Portal

On June 30th-July 1, 2022 the research team at Epicentre in Mbarara, Uganda held a two-day workshop about their recent work to address gaps in tuberculosis diagnostics and therapeutics in low-income countries. Sessions included:


• Landscape of TB disease in Uganda: research gaps

• New diagnostic tools and algorithms in adults

• New diagnostic tools and algorithms in children

• Approaches to increasing pediatric TB detection and reducing disease burden

• TB chemotherapeutics

• Perspectives and challenges in TB


To catch up on the presentations, you can view the abstracts through the link below.

Collection Content

Conference Material
|
Video

TB research dissemination workshop: key takeaways

Boum Y II
2022-07-01 • TB Research Dissemination Workshop, Epicentre Uganda
2022-07-01 • TB Research Dissemination Workshop, Epicentre Uganda
Conference Material
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Abstract

Acceptability and feasibility of a household child-contact investigation and preventive therapy management in Cameroon and Uganda

Vasiliu A
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
The CONTACT study (Cameroon, Uganda) is a cluster-randomized trial evaluating a community intervention for tuberculosis contact investigation and tuberculosis preventive treatment manage...
Conference Material
|
Abstract

COVID-19 in HIV-positive patients investigated for tuberculosis in the context of the FujiLAM study

Taremwa IM
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
People with immunosuppression may be particularly vulnerable to SARS-CoV-2 and some symptoms of infection by SARS-CoV-2 and TB are similar. Dual infection with both TB and...
Conference Material
|
Abstract

Evaluation of centrifuge-free stool processing methods combined with Xpert MTB/RIF ultra for diagnosis of intrathoracic paediatric TB

Kaitano R
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
There is a growing interest for the use of stool samples as an alternative to respiratory samples for the diagnosis of intrathoracic TB in children unable to produce sputu...
Conference Material
|
Abstract

Feasibility of implementing the FujiLAM assay and acceptability by health workers and patients

Muyindike WR
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
The novel urine-based FujiLAM test identifies tuberculosis in HIV-positive patients but may be challenging to use as a point-of-care (POC) test.

OBJECTIVES
We...
Conference Material
|
Abstract

Impact of systematic TB detection using Xpert Ultra on nasopharyngeal aspirates and stool samples on mortality in children with severe pneumonia

Mwanga-Amumpaire J
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
In children with severe pneumonia, TB is usually considered only in case of prolonged symptoms or antibiotic failure, leading to missed or delayed TB diagnosis. Systematic...
Conference Material
|
Abstract

Tuberculosis diagnostic accuracy of stool xpert MTB/RIF and urine alereLAM in vulnerable children

Nampijja D
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
Non-sputum-based diagnostic approaches are crucial in children at high risk of disseminated tuberculosis (TB) who cannot expectorate sputum. We evaluated the diagnostic ac...
Conference Material
|
Abstract

Diagnostic performance of the novel FujiLAM assay to detect tuberculosis in HIV-positive patients

Huerga H
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
The novel urine-based point-of-care FujiLAM assay is a promising tool for tuberculosis (TB) diagnosis. We prospectively assessed the diagnostic accuracy of FujiLAM and we ...
Conference Material
|
Abstract

Increased child contact investigation and tuberculosis preventive treatment management through a community-based intervention in Cameroon and Uganda: Results of the contact cluster randomized trial

Atwine D
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
CONTEXT
In tuberculosis (TB) endemic countries, the screening and management of household contacts remains low including the uptake of TB preventive treatment (TPT). One of the chall...
Conference Material
|
Abstract

Systematic or test-guided treatment for tuberculosis in HIV-infected adults

Muzoora C
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
In regions with high burdens of tuberculosis and human immunodeficiency virus (HIV), many HIV-infected adults begin antiretroviral therapy (ART) when they are already seve...

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Nursing care at MSF

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New tools and approaches to drug-resistant TB

New tools and approaches to drug-resistant TB
The World Health Organization estimates that 410,000 people developed a drug-resistant tuberculosis infection (DR-TB) in 2022, only 40% of whom were diagnosed and started on treatment—and only 63% then cured. Given all these points of failure, innovation in preventing, diagnosing and treating DR-TB cannot come fast enough. To mark World TB Day (24 March 2024) the content collection linked below highlights recent work by MSF and collaborators to help change this grim picture. The TB-PRACTECAL and endTB studies delivered robust evidence for shorter, safer, more effective drug regimens that are already saving lives worldwide. Other studies explore new approaches to preventive treatment and simpler, quicker, accurate detection of TB and drug resistance—especially among difficult-to-diagnose populations such as children and people living with HIV. But to impact DR-TB globally these innovations must become widely accessible. This requires changes on many fronts, as described in an accompanying Collection (Expanding Access to Lifesaving New TB Tools).
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TB Research Dissemination Workshop 2022

TB Research Dissemination Workshop 2022