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TB Research Dissemination Workshop 2022 | Collections | MSF Science Portal
TB Research Dissemination Workshop 2022

TB Research Dissemination Workshop 2022

On June 30th-July 1, 2022 the research team at Epicentre in Mbarara, Uganda held a two-day workshop about their recent work to address gaps in tuberculosis diagnostics and therapeutics in low-income countries. Sessions included:


• Landscape of TB disease in Uganda: research gaps

• New diagnostic tools and algorithms in adults

• New diagnostic tools and algorithms in children

• Approaches to increasing pediatric TB detection and reducing disease burden

• TB chemotherapeutics

• Perspectives and challenges in TB


To catch up on the presentations, you can view the abstracts through the link below.

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Diabetes care in humanitarian settings

Diabetes care in humanitarian settings
Diabetes affect hundreds of millions of people worldwide, a large majority of them living in low- and middle-income countries. Yet finding effective strategies, tools and policies for effectively managing this chronic illness—especially amid war, displacement or exclusion from care—is a neglected area of humanitarian medicine. Here we present a cross-section of work on this front by MSF and collaborators. Several studies assess the shift towards community-based, nurse-led models of care in rural settings. Others explore obstacles to diabetes care for war refugees living in camps in Jordan or Lebanon, highlighting how health programs can adapt to their needs. The demonstration that insulin retains potency for 30 days if cooled without refrigeration is opening doors to more patient self-management, as a case study in remote South Sudan shows. At the same time, MSF and others call for regulatory and financing policies that make diabetes medications and supplies cheaper, better adapted to humanitarian settings, and far more available to patients whose lives depend on them.
World Malaria Day 2023

World Malaria Day 2023
The endTB project

The endTB project
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World Malaria Day is April 25th. The theme for 2023 is "Zero malaria: invest, innovate, implement" and the importance of reaching marginalized populations with the tools and strategies that are currently available. This collection highlights research on this theme, especially the latter two "i's": From research on Seasonal Chemoprophylaxis (SMC) and mass drug administration (MDA), to analyzing the reach of gene mutations (HRP2) in new environments, to other interventional research topics, these articles show how innovative approaches can be successfully implemented even in the most challenging settings to fight this global public health threat.

The endTB project aims to find shorter, less toxic and more effective treatments for ‘multidrug-resistant TB’ (MDR-TB) through:

  • access to new drugs
  • two clinical trials
  • advocacy at national and global levels

Covering 18 countries, the project is a partnership between Partners In Health, Médecins Sans Frontières, Interactive Research & Development and financial partners Unitaid and the Transformational Investment Capacity (TIC) of MSF. This collection contains the final and intermediate results of the studies, advocacy reports, and study presentations. For more information about the endTB project, visit https://endtb.org/.

Conference Material
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Video

TB research dissemination workshop: key takeaways

Boum Y II
2022-07-01 • TB Research Dissemination Workshop, Epicentre Uganda
2022-07-01 • TB Research Dissemination Workshop, Epicentre Uganda
Conference Material
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Abstract

Acceptability and feasibility of a household child-contact investigation and preventive therapy management in Cameroon and Uganda

Vasiliu A
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
The CONTACT study (Cameroon, Uganda) is a cluster-randomized trial evaluating a community intervention for tuberculosis contact investigation and tuberculosis preventive treatment manage...
Conference Material
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Abstract

COVID-19 in HIV-positive patients investigated for tuberculosis in the context of the FujiLAM study

Taremwa IM
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
People with immunosuppression may be particularly vulnerable to SARS-CoV-2 and some symptoms of infection by SARS-CoV-2 and TB are similar. Dual infection with both TB and...
Conference Material
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Abstract

Evaluation of centrifuge-free stool processing methods combined with Xpert MTB/RIF ultra for diagnosis of intrathoracic paediatric TB

Kaitano R
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
There is a growing interest for the use of stool samples as an alternative to respiratory samples for the diagnosis of intrathoracic TB in children unable to produce sputu...
Conference Material
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Abstract

Feasibility of implementing the FujiLAM assay and acceptability by health workers and patients

Muyindike WR
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
The novel urine-based FujiLAM test identifies tuberculosis in HIV-positive patients but may be challenging to use as a point-of-care (POC) test.

OBJECTIVES
We...
Conference Material
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Abstract

Impact of systematic TB detection using Xpert Ultra on nasopharyngeal aspirates and stool samples on mortality in children with severe pneumonia

Mwanga-Amumpaire J
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
In children with severe pneumonia, TB is usually considered only in case of prolonged symptoms or antibiotic failure, leading to missed or delayed TB diagnosis. Systematic...
Conference Material
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Abstract

Tuberculosis diagnostic accuracy of stool xpert MTB/RIF and urine alereLAM in vulnerable children

Nampijja D
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
Non-sputum-based diagnostic approaches are crucial in children at high risk of disseminated tuberculosis (TB) who cannot expectorate sputum. We evaluated the diagnostic ac...
Conference Material
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Abstract

Diagnostic performance of the novel FujiLAM assay to detect tuberculosis in HIV-positive patients

Huerga H
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
The novel urine-based point-of-care FujiLAM assay is a promising tool for tuberculosis (TB) diagnosis. We prospectively assessed the diagnostic accuracy of FujiLAM and we ...
Conference Material
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Abstract

Increased child contact investigation and tuberculosis preventive treatment management through a community-based intervention in Cameroon and Uganda: Results of the contact cluster randomized trial

Atwine D
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
CONTEXT
In tuberculosis (TB) endemic countries, the screening and management of household contacts remains low including the uptake of TB preventive treatment (TPT). One of the chall...
Conference Material
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Abstract

Systematic or test-guided treatment for tuberculosis in HIV-infected adults

Muzoora C
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
2022-06-29 • TB Research Dissemination Workshop, Epicentre Uganda
BACKGROUND
In regions with high burdens of tuberculosis and human immunodeficiency virus (HIV), many HIV-infected adults begin antiretroviral therapy (ART) when they are already seve...