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Treatment and outcomes in children with multidrug-resistant tuberculosis: A systematic review and individual patient data meta-analysis | Journal Article / Research | MSF Science Portal
Journal Article
|Research

Treatment and outcomes in children with multidrug-resistant tuberculosis: A systematic review and individual patient data meta-analysis

Harausz EP, Garcia-Prats AJ, Law S, Schaaf HS, Kredo T, Seddon JA, Menzies D, Turkova A, Achar J, Amanullah F, Barry PM, Becerra M, Chan ED, Chan PL, Ioana Chiotan D, Crossa A, Drobac PC, Fairlie L, Falzon D, Flood J, Gegia M, Hicks RM, Isaakidis P, Kadri S, Kampmann B, Madhi SA, Marais E, Mariandyshev A, Méndez-Echevarría A, Moore BR, Nargiza P, Ozere I, Padayatchi N, ur-Rehman S, Rybak N, Santiago-Garcia B, Shah NS, Sharma SK, Shim TS, Skrahina A, Soriano-Arandes A, van den Boom M, van der Werf MJ, van der Werf TS, Williams BG, Yablokova E, Yim JJ, Furin J, Hesseling AC
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Abstract
An estimated 32,000 children develop multidrug-resistant tuberculosis (MDR-TB; Mycobacterium tuberculosis resistant to isoniazid and rifampin) each year. Little is known about the optimal treatment for these children.

Subject Area

tuberculosis

Languages

English
DOI
10.1371/journal.pmed.1002591
Published Date
11 Jul 2018
PubMed ID
29995958
Journal
PLOS Medicine
Volume | Issue | Pages
Volume 15, Issue 7, Pages e1002591
Issue Date
2018-07-11
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