Search Results | MSF Science Portal

Journal Article

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Research

Schilling WHK, Mukaka M, Callery JJ, Llewelyn MJ, Cruz CV, et al.

2024-09-12 • PLOS Medicine

BACKGROUND

Hydroxychloroquine (HCQ) has proved ineffective in treating patients hospitalised with Coronavirus Disease 2019 (COVID-19), but uncertainty remains over its safety an...

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Commentary

Gerdin M, Clarke M, Allen C, Kayabu B, Summerskill W, et al.

2014-04-22 • PLOS Medicine

Martin Gerdin and colleagues argue that disaster health interventions and decision-making can benefit from an evidence-based approach Please see later in the article for the Editors' Sum...

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Commentary

Minetti A, Bopp C, Fermon F, Francois G, Grais RF, et al.

2013-11-05 • PLOS Medicine

Andrea Minetti and colleagues compare measles outbreak responses from the Democratic Republic of the Congo and Malawi and argue that outbreak response strategies should be tailored to lo...

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Research

Dentico N, Ford NP

2005-02-01 • PLOS Medicine

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Commentary

Ford NP, Geng EH, Ellman T, Orrell C, Ehrenkranz PD, et al.

2020-02-14 • PLOS Medicine

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Research

Gupta-Wright A, Corbett EL, Wilson D, van Oosterhout JJ, Dheda K, et al.

2019-04-05 • PLOS Medicine

The prevalence of and mortality from HIV-associated tuberculosis (HIV/TB) in hospital inpatients in Africa remains unacceptably high. Currently, there is a lack of tools to identify thos...

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Research

Schluger N, Karunakara U, Lienhardt C, Nyirenda T, Chaisson RE

2007-11-06 • PLOS Medicine

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Research

Boulle AM, Schomaker M, May MT, Hogg RS, Shepherd B, et al.

2014-09-09 • PLOS Medicine

BACKGROUND
High early mortality in patients with HIV-1 starting antiretroviral therapy (ART) in sub-Saharan Africa, compared to Europe and North America, is well documented. Longer-t...

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Research

Polonsky JA, Ivey M, Mazhar KA, Rahman Z, le Polain de Waroux O, et al.

2021-04-01 • PLOS Medicine

BACKGROUND
Unrest in Myanmar in August 2017 resulted in the movement of over 700,000 Rohingya refugees to overcrowded camps in Cox's Bazar, Bangladesh. A large outbreak of diphtheria...

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Commentary

Schopper D, Upshur R, Matthys F, Singh JA, Bandewar SS, et al.

2009-07-28 • PLOS Medicine

Doris Schopper and colleagues describe the functioning of the Médecins Sans Frontières independent ethics review board and the framework used for ethics review, and discuss challenging e...

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Research

Keitel K, Kagoro F, Samaka J, Masimba J, Said Z, et al.

2017-10-23 • PLOS Medicine

The management of childhood infections remains inadequate in resource-limited countries, resulting in high mortality and irrational use of antimicrobials. Current disease management tool...

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Commentary

Sheather J, Jobanputra K, Schopper D, Pringle J, Venis S, et al.

2016-09-06 • PLOS Medicine

SUMMARY POINTS

• Humanitarian organisations often have to innovate to deliver health care and aid to populations in complex and volatile contexts.

• Innovation projec...

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Commentary

Ehrenkranz PD, Baptiste SL, Bygrave H, Ellman T, Doi N, et al.

2019-05-29 • PLOS Medicine

In a Policy Forum, Peter Ehrenkranz and colleagues discuss the contribution of CD4 and viral load testing to outcomes for people with HIV in low- and middle-income countries.

Journal Article

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Research

Isanaka S, Garba S, Plikaytis BD, McNeal MM, Guindo O, et al.

2021-08-10 • PLOS Medicine

BACKGROUND
Nutritional status may play a role in infant immune development. To identify potential boosters of immunogenicity in low-income countries where oral vaccine efficacy is lo...

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Research

Sissoko D, Laouenan C, Folkesson E, M’Lebing A, Beavogui A, et al.

2016-03-01 • PLOS Medicine

Ebola virus disease (EVD) is a highly lethal condition for which no specific treatment has proven efficacy. In September 2014, while the Ebola outbreak was at its peak, the World Health ...

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Research

Cox HS, Kebede YYK, Allamuratova S, Ismailov G, Davletmuratova Z, et al.

2006-10-01 • PLOS Medicine

BACKGROUND: The DOTS (directly observed treatment short-course) strategy for tuberculosis (TB) control is recommended by the World Health Organization globally. However, there are few st...

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Research

Hitchings MD, Berthe F, Aruna P, Shehu I, Ali Hamza M, et al.

2022-03-01 • PLOS Medicine

BACKGROUND
Community-based management of severe acute malnutrition (SAM) involves weekly or biweekly outpatient clinic visits for clinical surveillance and distribution of therapeuti...

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Research

Huerga H, Rucker SCM, Cossa L, Bastard M, Amoros I, et al.

2019-04-30 • PLOS Medicine

BACKGROUND:
Current guidelines recommend the use of the lateral flow urine lipoarabinomannan assay (LAM) in HIV-positive, ambulatory patients with signs and symptoms of tuberculosis...

Journal Article

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Commentary

van den Berg W, Brittain K, Mercer G, Peacock D, Stinson K, et al.

2015-04-07 • PLOS Medicine

SUMMARY POINTS

-- Involving male partners in programmes to prevent mother-to-child transmission of HIV may improve programme coverage and infant outcomes.
-- Rates of male p...

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Commentary

Balsegaram M, Brechot C, Farrar J, Heymann D, Ganguly N, et al.

2015-05-11 • PLOS Medicine

Bernard Pécoul and colleagues call for the establishment of a global biomedical R&D fund as a key priority of the G7 summit in June 2015.

Science Portal

Evaluation of hydroxychloroquine or chloroquine for the prevention of COVID-19 (COPCOV): A double-blind, randomised, placebo-controlled trial

Optimal evidence in difficult settings: improving health interventions and decision making in disasters

Measles outbreak response immunization is context-specific: insight from the recent experience of médecins sans frontières

The courage to change the rules: a proposal for an essential health R&D treaty

Emerging priorities for HIV service delivery

Risk score for predicting mortality including urine lipoarabinomannan detection in hospital inpatients with HIV-associated tuberculosis in sub-Saharan Africa: Derivation and external validation cohort study

Building clinical trials capacity for tuberculosis drugs in high-burden countries

Mortality in patients with HIV-1 infection starting antiretroviral therapy in South Africa, Europe, or North America: a collaborative analysis of prospective studies

Epidemiological, clinical, and public health response characteristics of a large outbreak of diphtheria among the Rohingya population in Cox's Bazar, Bangladesh, 2017 to 2019: A retrospective study

Research ethics review in humanitarian contexts: the experience of the independent Ethics Review Board of Médecins Sans Frontières

A Novel Electronic Algorithm using Host Biomarker Point-of-Care tests for the Management of Febrile Illnesses in Tanzanian children (e-POCT): A randomized, controlled non-inferiority trial

A Médecins Sans Frontières ethics framework for humanitarian innovation

The missed potential of CD4 and viral load testing to improve clinical outcomes for people living with HIV in lower-resource settings

Immunogenicity of an oral rotavirus vaccine administered with prenatal nutritional support in Niger: A cluster randomized clinical trial

Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea

Tuberculosis recurrence and mortality after successful treatment: impact of drug resistance

Effectiveness of a monthly schedule of follow-up for the treatment of uncomplicated severe acute malnutrition in Sokoto, Nigeria: a cluster randomized crossover trial

Diagnostic value of the urine lipoarabinomannan assay in HIV-positive, ambulatory patients with CD4 below 200 cells/μl in 2 low-resource settings: A prospective observational study.

Improving men's participation in preventing mother-to-child transmission of HIV as a maternal, neonatal, and child health priority in South Africa

A Global Biomedical R&D Fund and Mechanism for Innovations of Public Health Importance