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Long duration and resurgence of SARS-CoV-2 in Cameroonian population | Journal Article / Pre-Print | MSF Science Portal
Journal Article
|Pre-Print

Long duration and resurgence of SARS-CoV-2 in Cameroonian population

Buri D, Njuwa FK, Matchim L, Akendji B, Eteki L, Fouda NM, Bebell LM, Ndifon M, Hamadou A, Dora T, Nicolay B, Abbah A, Tchoula C, Kameni BT, Rene E, Nsaibirni R, Ntone R, Fanne M, Eyangoh S, Ouamba JP, Koku MT, Mandeng N, Esso L, Marie Claire O, Epee E, Mballa GAE, Njouom R
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Abstract
BACKGROUND
Infection with SARS-CoV-2 can lead to a detectable serological immune response even though extent of its protection is still not yet well known. We report long duration and resurgence of SARS-CoV-2 in patients with COVID-19.

METHODS
We included a cohort of 99 participants from our non-blinded non-randomized evaluation of COVID-19 tests in Cameroon. Demographic and clinical information was collected from participants including self-reported age, race, ethnicity, and gender. Qualitative data was described as proportions while quantitative data was described with means and accompanying ranges.

RESULTS
Duration of PCR for SARS-CoV-2 positivity was found to range from 4 – 81 days, with mean duration of 32.8 days in patients with PCR-positive. We also identified 4 participants who also had SARS-CoV-2 resurgence within a three-month period.

CONCLUSION
These observations raise questions on clinical decision to release COVID-19 cases from isolation after 14 days.

Countries

Cameroon

Subject Area

Covid-19

Languages

English
DOI
10.21203/rs.3.rs-156679/v1
Published Date
02 Feb 2021
Journal
Research Square
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