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Journal Article > Short Report

First Newborn Baby to Receive Experimental Therapies Survives Ebola Virus Disease

Dornemann J, Burzio C, Ronsse A, Sprecher A, De Clerck H, Van Herp M, Kolie MC, Yosifiva V, Caluwaerts C, McElroy AK, Antierens A
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Abstract
A neonate born to an Ebola virus-positive woman was diagnosed with Ebola virus infection on her first day of life. The patient was treated with monoclonal antibodies (ZMapp), a buffy coat transfusion from an Ebola survivor, and the broad-spectrum antiviral GS-5734. On day 20, a venous blood specimen tested negative for Ebola virus by quantitative reverse-transcription polymerase chain reaction. The patient was discharged in good health on day 33 of life. Further follow-up consultations showed age-appropriate weight gain and neurodevelopment at the age of 12 months. This patient is the first neonate documented to have survived congenital infection with Ebola virus.
Countries
Guinea
Subject Area
Ebola
DOI
10.1093/infdis/jiw493
Published Date
15-Jan-2017
PubMed ID
28073857
Languages
English
Journal
Journal of Infectious Diseases
Issue Date
09-Jan-2017
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