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Journal Article > Research

Evaluation of combined LED-fluorescence microscopy and bleach sedimentation for diagnosis of tuberculosis at peripheral health service level

Bonnet MMB, Gagnidze L, Guerin PJ, Bonte L, Ramsay AR, Githui W, Varaine FFV
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Abstract
Sputum microscopy is the only diagnostic for tuberculosis (TB) available at peripheral levels of health service in resource-poor countries. Its sensitivity is reduced in high HIV-prevalence settings. Sodium hypochlorite (NaOCl) specimen sedimentation prior microscopy and light-emitting diode (LED)-fluorescence microscopy (FM) can individually improve performance of microscopy. This study aimed to evaluate the performance of combined LED-FM and NaOCl sputum sedimentation for TB detection at peripheral level of health services.
Countries
Kenya
Subject Area
tuberculosisdiagnostics
DOI
10.1371/journal.pone.0020175
Published Date
31-May-2011
PubMed ID
21655284
Languages
English
Journal
PLOS One
Volume / Issue / Pages
Volume 6, Issue 5
Issue Date
31-May-2011
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