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Effect of a serogroup A meningococcal conjugate vaccine (PsA-TT) on serogroup A meningococcal meningitis and carriage in Chad: a community trial | Journal Article / Research | MSF Science Portal
Journal Article
|Research

Effect of a serogroup A meningococcal conjugate vaccine (PsA-TT) on serogroup A meningococcal meningitis and carriage in Chad: a community trial

Daugla DM, Gami JP, Gamougam K, Naibei N, Mbainadji L, Narbe M, Toralta J, Kodbesse B, Ngadoua C, Coldiron ME, Fermon F, Page AL, Djingarey MH, Harrison OB, Rebbetts LS, Tekletsion Y, Watkins ER, Hill DC, Caugant DA, Chandramohan D, Hassan-King M, Manigart O, Nascimento M, Woukeu A, Trotter C, Stuart JM, Maiden MCJ, Greenwood BM
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Abstract
A serogroup A meningococcal polysaccharide-tetanus toxoid conjugate vaccine (PsA-TT, MenAfriVac) was licensed in India in 2009, and pre-qualified by WHO in 2010, on the basis of its safety and immunogenicity. This vaccine is now being deployed across the African meningitis belt. We studied the effect of PsA-TT on meningococcal meningitis and carriage in Chad during a serogroup A meningococcal meningitis epidemic.

Countries

Chad

Subject Area

vaccinationmeningitisdisease surveillance

Languages

English
DOI
10.1016/S0140-6736(13)61612-8
Published Date
04 Jan 2014
PubMed ID
24035220
Journal
Lancet
Volume | Issue | Pages
Volume 383, Issue 9911
Issue Date
2014-01-01
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