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Development of a cross-over randomized trial method to determine the acceptability and safety of novel ready-to-use therapeutic foods | Journal Article / Research | MSF Science Portal
Journal Article
|Research

Development of a cross-over randomized trial method to determine the acceptability and safety of novel ready-to-use therapeutic foods

Dibari F, Bahwere P, Huerga H, Hailu ADE, Owino V, Collins S, Seal AJ
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Abstract
To develop a method for determining the acceptability and safety of ready-to-use therapeutic foods (RUTF) before clinical trialing. Acceptability was defined using a combination of three consumption, nine safety, and six preference criteria. These were used to compare a soy/maize/sorghum RUTF (SMS-RUTFh), designed for the rehabilitation of human immunodeficiency virus/tuberculosis (HIV/TB) wasted adults, with a peanut-butter/milk-powder paste (P-RUTF; brand: Plumpy'nut) designed for pediatric treatment.

Countries

Kenya

Subject Area

malnutrition

Languages

English
DOI
10.1016/j.nut.2012.04.016
Published Date
01 Jan 2013
PubMed ID
22981306
Journal
BMC Nutrition
Volume | Issue | Pages
Volume 29, Issue 1
Issue Date
2013-01-01
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