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Showing 1 - 20 of 21 Items
Showing 1 - 20 of 21 Items
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Poster

Les medicaments de la CPS sous la loupe

Grandesso F, Ouedraogo P, Issakha Diar MS, Hilario JS, Kouassi F,  et al.
2024-05-23 • Epicentre Scientific Day 2024
2024-05-23 • Epicentre Scientific Day 2024
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Pre-Print
Conference Material
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Video

Efficacy and safety of Triple ACTs compared to conventional ACTs for the treatment of uncomplicated malaria: preliminary results of the DeTACT trial in Niger

Ngoumboute I
2023-06-08 • Epicentre Scientific Day Paris 2023
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Efficacy of amodiaquine in uncomplicated falciparum malaria in Nigeria in an area with high-level resistance to chloroquine and sulphadoxine/pyrimethamine

Journal Article
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Mixed-method evaluation study of a targeted mass drug administration of long-acting anti-malarials among children aged 3 months to 15 years in the Bossangoa sub-prefecture, Ouham, Central African Republic, during the COVID-19 pandemic

Robinson E, Ouabo A, Rose L, van Braak F, Vyncke J,  et al.
2024-05-15 • Malaria Journal
2024-05-15 • Malaria Journal
BACKGROUND
In 2020, during the COVID-19 pandemic, Médecins Sans Frontières (MSF) initiated three cycles of dihydroartemisin-piperaquine (DHA-PQ) mass drug administration (MDA) for ch...

Implementation of post-discharge malaria chemoprevention (PDMC) in Benin, Kenya, Malawi, and Uganda: Stakeholder engagement meeting report

Hill J, Accrombessi M, Briand V, Dhabangi A, Hoyt J,  et al.
2024-03-27 • Malaria Journal
2024-03-27 • Malaria Journal

A Stakeholder engagement meeting on the implementation of post-discharge malaria chemoprevention (PDMC) in Benin, Kenya, Malawi, and Uganda was held in Nairobi, Kenya, on 27 September...

Genetic diversity and allelic variability of pfmsp1 y pfmsp2 of P. falciparum and its association with syntomatology and antimalarial drugs resistance markers in Yambio county, South Sudan

Fuente IMdl, Benito MJS, Gisbert FB, García L, González V,  et al.
2024-02-21 • Malaria Journal
2024-02-21 • Malaria Journal
BACKGROUND
Malaria genetic diversity is an important indicator of malaria transmission. Pfmsp1 and pfmsp2 are a frequent molecular epidemiology tool to assess the genetic diversity. ...
2023-06-08 • Epicentre Scientific Day Paris 2023

Efficacy and safety of Triple ACTs compared to conventional ACTs for the treatment of uncomplicated malaria: preliminary results of the DeTACT trial in Niger

Ngoumboute I
2023-06-08 • Epicentre Scientific Day Paris 2023
2023-06-08 • Epicentre Scientific Day Paris 2023
INTRODUCTION
Artemisinin-based combination therapies (ACTs) have made a major contribution to substantial reductions in malaria morbidity and mortality worldwide over the past decade...

Efficacy of artesunate-amodiaquine for treating uncomplicated falciparum malaria in sub-Saharan Africa: a multi-centre analysis

Zwang J, Olliaro PL, Barennes H, Bonnet MMB, Brasseur P,  et al.
2009-08-23 • Malaria Journal
2009-08-23 • Malaria Journal
BACKGROUND: Artesunate and amodiaquine (AS&AQ) is at present the world's second most widely used artemisinin-based combination therapy (ACT). It was necessary to evaluate the efficacy of...

Comparison of chloroquine, sulfadoxine/pyrimethamine, mefloquine and mefloquine-artesunate for the treatment of falciparum malaria in Kachin State, North Myanmar

Smithuis FM, Shahmanesh M, Kyaw MK, Savran O, Lwin S,  et al.
2004-11-01 • Tropical Medicine and International Health
2004-11-01 • Tropical Medicine and International Health
Multi-drug resistant falciparum malaria is widespread in Asia. In Thailand, Cambodia and Vietnam the national protocols have changed largely to artesunate combined treatment regimens but...

Malaria profiles and challenges in artemisinin resistance containment in Myanmar

Nwe TW, Oo T, Wai KT, Zhou SS, van Griensven J,  et al.
2017-04-25 • Infectious Diseases of Poverty
2017-04-25 • Infectious Diseases of Poverty
BACKGROUND
This study examined evolving malaria profiles from January, 2010 to December, 2014 to evaluate achievements and challenges of implementing measures to prevent and control ...

Antimalarial efficacy of sulfadoxine-pyrimethamine, amodiaquine and a combination of chloroquine plus sulfadoxine-pyrimethamine in Bundi Bugyo, western Uganda

Checchi F, Piola P, Kosack CS, Ardizzoni E, Klarkowski DB,  et al.
2004-04-01 • Tropical Medicine and International Health
2004-04-01 • Tropical Medicine and International Health
We report below an in vivo antimalarial efficacy study conducted in 2002 in Bundi Bugyo, a district of western Uganda housing a large displaced population. We tested sulfadoxine-pyrimeth...

Assessing antimalarial efficacy in a time of change to artemisinin-based combination therapies: The role of Médecins Sans Frontières

Guthmann JP, Checchi F, van den Broek IVF, Balkan S, Van Herp M,  et al.
2008-08-05 • PLOS Medicine
2008-08-05 • PLOS Medicine

In vivo efficacy of artesunate-amodiaquine and artemether-lumefantrine for the treatment of uncomplicated falciparum malaria: an open-randomized, non-inferiority clinical trial in South Kivu, Democratic Republic of Congo

de Wit MBK, Funk A, Moussally K, Nkuba DA, Siddiqui R,  et al.
2016-09-06 • Malaria Journal
2016-09-06 • Malaria Journal
BACKGROUND
Between 2009 and 2012, malaria cases diagnosed in a Médecins sans Frontières programme have increased fivefold in Baraka, South Kivu, Democratic Republic of the Congo (DRC...

Efficacy of artesunate-amodiaquine and artemether-lumefantrine fixed-dose combinations for the treatment of uncomplicated Plasmodium falciparum malaria among children aged six to 59 months in Nimba County, Liberia: an open-label randomized non-inferiority trial

Schramm B, Valeh P, Baudin E, Mazinda CS, Smith R,  et al.
2013-07-17 • Malaria Journal
2013-07-17 • Malaria Journal
BACKGROUND
Prospective efficacy monitoring of anti-malarial treatments is imperative for timely detection of resistance development. The in vivo efficacy of artesunate-amodiaquine (A...

Insecticide resistance profiles in malaria vector populations from Sud-Kivu in the Democratic Republic of the Congo

N'do S, Bandibabone JB, Soma DD, Musaka BZ, Prudhomme J,  et al.
2021-11-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2021-11-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
BACKGROUND
Insecticide resistance has become a widespread problem causing a decline in the effectiveness of vector control tools in sub-Saharan Africa. In this situation, ongoing mon...

Efficacy of artesunate-amodiaquine, dihydroartemisinin-piperaquine and artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Maradi, Niger

Grandesso F, Guindo O, Woi-Messe LC, Makarimi R, Traore A,  et al.
2018-01-25 • Malaria Journal
2018-01-25 • Malaria Journal
BACKGROUND
Malaria endemic countries need to assess efficacy of anti-malarial treatments on a regular basis. Moreover, resistance to artemisinin that is established across mainland S...

Competing risk events in antimalarial drug trials in uncomplicated Plasmodium falciparum malaria: a WorldWide Antimalarial Resistance Network individual participant data meta-analysis

WorldWide Antimalarial Resistance Network Methodology Study Group, Dahal P, Simpson JA, Abdulla S, Achan J,  et al.
2019-07-05 • Malaria Journal
2019-07-05 • Malaria Journal
BACKGROUND
Therapeutic efficacy studies in uncomplicated Plasmodium falciparum malaria are confounded by new infections, which constitute competing risk events since they can potenti...

Methodological issues in the assessment of antimalarial drug treatment: Analysis of 13 studies in eight African countries from 2001 to 2004

Guthmann JP, Pinoges LLP, Checchi F, Cousens S, Balkan S,  et al.
2006-11-01 • Antimicrobial Agents and Chemotherapy
2006-11-01 • Antimicrobial Agents and Chemotherapy
The objectives of these analyses were to assess the feasibility of the latest WHO recommendations (28-day follow-up with PCR genotyping) for the assessment of antimalarial drug efficacy ...
Graupner J, Göbels K, Grobusch MP, Lund A, Richter J,  et al.
2005-04-28 • Parasitology Research
2005-04-28 • Parasitology Research
Falciparum malaria is hyperendemic in southern Nigeria and chloroquine resistance is an increasing problem. Therefore, the parasitological and haematological response to treatment with a...

Different methodological approaches to the assessment of in vivo efficacy of three artemisinin-based combination antimalarial treatments for the treatment of uncomplicated falciparum malaria in African children

Ashley EA, Pinoges LLP, Turyakira E, Dorsey G, Checchi F,  et al.
2008-08-09 • Malaria Journal
2008-08-09 • Malaria Journal
BACKGROUND: Use of different methods for assessing the efficacy of artemisinin-based combination antimalarial treatments (ACTs) will result in different estimates being reported, with im...

Antimalarial efficacy of chloroquine, amodiaquine, sulfadoxine-pyrimethamine, and the combinations of amodiaquine + artesunate and sulfadoxine-pyrimethamine + artesunate in Huambo and Bie provinces, central Angola

Guthmann JP, Ampuero J, Fortes F, Van Overmeir C, Gaboulaud V,  et al.
2005-07-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2005-07-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
We studied three antimalarial treatments in Caala and Kuito, Angola, in 2002 and 2003. We tested chloroquine (CQ), amodiaquine (AQ) and sulfadoxine-pyrimethamine (SP) in Caala, and AQ, S...