Search Results | MSF Science Portal

Conference Material

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Poster

Grandesso F, Ouedraogo P, Issakha Diar MS, Hilario JS, Kouassi F, et al.

2024-05-23 • Epicentre Scientific Day 2024

Journal Article

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Research

Robinson E, Ouabo A, Rose L, van Braak F, Vyncke J, et al.

2024-05-15 • Malaria Journal

BACKGROUND
In 2020, during the COVID-19 pandemic, Médecins Sans Frontières (MSF) initiated three cycles of dihydroartemisin-piperaquine (DHA-PQ) mass drug administration (MDA) for ch...

Journal Article

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Pre-Print

Fuente IMdl, Benito MJS, Gisbert FB, García L, González V, et al.

2024-02-21 • Malaria Journal

BACKGROUND
Malaria genetic diversity is an important indicator of malaria transmission. Pfmsp1 and pfmsp2 are a frequent molecular epidemiology tool to assess the genetic diversity. ...

Conference Material

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Video

Ngoumboute I

2023-06-08 • Epicentre Scientific Day Paris 2023

Conference Material

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Abstract

Ngoumboute I

2023-06-08 • Epicentre Scientific Day Paris 2023

INTRODUCTION
Artemisinin-based combination therapies (ACTs) have made a major contribution to substantial reductions in malaria morbidity and mortality worldwide over the past decade...

Journal Article

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Research

Zwang J, Olliaro PL, Barennes H, Bonnet MMB, Brasseur P, et al.

2009-08-23 • Malaria Journal

BACKGROUND: Artesunate and amodiaquine (AS&AQ) is at present the world's second most widely used artemisinin-based combination therapy (ACT). It was necessary to evaluate the efficacy of...

Journal Article

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Research

Smithuis FM, Shahmanesh M, Kyaw MK, Savran O, Lwin S, et al.

2004-11-01 • Tropical Medicine and International Health

Multi-drug resistant falciparum malaria is widespread in Asia. In Thailand, Cambodia and Vietnam the national protocols have changed largely to artesunate combined treatment regimens but...

Journal Article

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Research

Nwe TW, Oo T, Wai KT, Zhou SS, van Griensven J, et al.

2017-04-25 • Infectious Diseases of Poverty

BACKGROUND
This study examined evolving malaria profiles from January, 2010 to December, 2014 to evaluate achievements and challenges of implementing measures to prevent and control ...

Journal Article

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Research

Guthmann JP, Checchi F, van den Broek IVF, Balkan S, Van Herp M, et al.

2008-08-05 • PLOS Medicine

Journal Article

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Research

Checchi F, Piola P, Kosack CS, Ardizzoni E, Klarkowski DB, et al.

2004-04-01 • Tropical Medicine and International Health

We report below an in vivo antimalarial efficacy study conducted in 2002 in Bundi Bugyo, a district of western Uganda housing a large displaced population. We tested sulfadoxine-pyrimeth...

Journal Article

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Research

N'do S, Bandibabone JB, Soma DD, Musaka BZ, Prudhomme J, et al.

2021-11-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene

BACKGROUND
Insecticide resistance has become a widespread problem causing a decline in the effectiveness of vector control tools in sub-Saharan Africa. In this situation, ongoing mon...

Journal Article

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Research

de Wit MBK, Funk A, Moussally K, Nkuba DA, Siddiqui R, et al.

2016-09-06 • Malaria Journal

BACKGROUND
Between 2009 and 2012, malaria cases diagnosed in a Médecins sans Frontières programme have increased fivefold in Baraka, South Kivu, Democratic Republic of the Congo (DRC...

Journal Article

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Research

Schramm B, Valeh P, Baudin E, Mazinda CS, Smith R, et al.

2013-07-17 • Malaria Journal

BACKGROUND
Prospective efficacy monitoring of anti-malarial treatments is imperative for timely detection of resistance development. The in vivo efficacy of artesunate-amodiaquine (A...

Journal Article

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Research

Grandesso F, Guindo O, Woi-Messe LC, Makarimi R, Traore A, et al.

2018-01-25 • Malaria Journal

BACKGROUND
Malaria endemic countries need to assess efficacy of anti-malarial treatments on a regular basis. Moreover, resistance to artemisinin that is established across mainland S...

Journal Article

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Research

Guthmann JP, Pinoges LLP, Checchi F, Cousens S, Balkan S, et al.

2006-11-01 • Antimicrobial Agents and Chemotherapy

The objectives of these analyses were to assess the feasibility of the latest WHO recommendations (28-day follow-up with PCR genotyping) for the assessment of antimalarial drug efficacy ...

Journal Article

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Research

Graupner J, Göbels K, Grobusch MP, Lund A, Richter J, et al.

2005-04-28 • Parasitology Research

Falciparum malaria is hyperendemic in southern Nigeria and chloroquine resistance is an increasing problem. Therefore, the parasitological and haematological response to treatment with a...

Journal Article

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Research

WorldWide Antimalarial Resistance Network Methodology Study Group, Dahal P, Simpson JA, Abdulla S, Achan J, et al.

2019-07-05 • Malaria Journal

BACKGROUND
Therapeutic efficacy studies in uncomplicated Plasmodium falciparum malaria are confounded by new infections, which constitute competing risk events since they can potenti...

Journal Article

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Research

Ashley EA, Pinoges LLP, Turyakira E, Dorsey G, Checchi F, et al.

2008-08-09 • Malaria Journal

BACKGROUND: Use of different methods for assessing the efficacy of artemisinin-based combination antimalarial treatments (ACTs) will result in different estimates being reported, with im...

Journal Article

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Research

Checchi F, Roddy P, Kamara S, Williams A, Morineau G, et al.

2005-02-01 • Tropical Medicine and International Health

OBJECTIVES: To provide nationally relevant information on the antimalarial efficacy of chloroquine (CQ), sulphadoxine-pyrimethamine (SP) and amodiaquine (AQ) in Sierra Leone, with a view...

Journal Article

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Research

Guthmann JP, Ampuero J, Fortes F, Van Overmeir C, Gaboulaud V, et al.

2005-07-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene

We studied three antimalarial treatments in Caala and Kuito, Angola, in 2002 and 2003. We tested chloroquine (CQ), amodiaquine (AQ) and sulfadoxine-pyrimethamine (SP) in Caala, and AQ, S...

Science Portal

Les medicaments de la CPS sous la loupe

Mixed-method evaluation study of a targeted mass drug administration of long-acting anti-malarials among children aged 3 months to 15 years in the Bossangoa sub-prefecture, Ouham, Central African Republic, during the COVID-19 pandemic

Genetic diversity and allelic variability of pfmsp1 y pfmsp2 of P. falciparum and its association with syntomatology and antimalarial drugs resistance markers in Yambio county, South Sudan

Efficacy and safety of Triple ACTs compared to conventional ACTs for the treatment of uncomplicated malaria: preliminary results of the DeTACT trial in Niger

Efficacy and safety of Triple ACTs compared to conventional ACTs for the treatment of uncomplicated malaria: preliminary results of the DeTACT trial in Niger

Efficacy of artesunate-amodiaquine for treating uncomplicated falciparum malaria in sub-Saharan Africa: a multi-centre analysis

Comparison of chloroquine, sulfadoxine/pyrimethamine, mefloquine and mefloquine-artesunate for the treatment of falciparum malaria in Kachin State, North Myanmar

Malaria profiles and challenges in artemisinin resistance containment in Myanmar

Assessing antimalarial efficacy in a time of change to artemisinin-based combination therapies: The role of Médecins Sans Frontières

Antimalarial efficacy of sulfadoxine-pyrimethamine, amodiaquine and a combination of chloroquine plus sulfadoxine-pyrimethamine in Bundi Bugyo, western Uganda

Insecticide resistance profiles in malaria vector populations from Sud-Kivu in the Democratic Republic of the Congo

In vivo efficacy of artesunate-amodiaquine and artemether-lumefantrine for the treatment of uncomplicated falciparum malaria: an open-randomized, non-inferiority clinical trial in South Kivu, Democratic Republic of Congo

Efficacy of artesunate-amodiaquine and artemether-lumefantrine fixed-dose combinations for the treatment of uncomplicated Plasmodium falciparum malaria among children aged six to 59 months in Nimba County, Liberia: an open-label randomized non-inferiority trial

Efficacy of artesunate-amodiaquine, dihydroartemisinin-piperaquine and artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Maradi, Niger

Methodological issues in the assessment of antimalarial drug treatment: Analysis of 13 studies in eight African countries from 2001 to 2004

Efficacy of amodiaquine in uncomplicated falciparum malaria in Nigeria in an area with high-level resistance to chloroquine and sulphadoxine/pyrimethamine

Competing risk events in antimalarial drug trials in uncomplicated Plasmodium falciparum malaria: a WorldWide Antimalarial Resistance Network individual participant data meta-analysis

Different methodological approaches to the assessment of in vivo efficacy of three artemisinin-based combination antimalarial treatments for the treatment of uncomplicated falciparum malaria in African children

Evidence basis for antimalarial policy change in Sierra Leone: five in vivo efficacy studies of chloroquine, sulphadoxine-pyrimethamine and amodiaquine

Antimalarial efficacy of chloroquine, amodiaquine, sulfadoxine-pyrimethamine, and the combinations of amodiaquine + artesunate and sulfadoxine-pyrimethamine + artesunate in Huambo and Bie provinces, central Angola