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Showing 1 - 20 of 28 Items
Showing 1 - 20 of 28 Items
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Journal Article
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Research

Perceptions, attitudes, and willingness of healthcare and frontline workers to participate in an Ebola vaccine trial in Uganda

Kimbugwe G, Vatrinet R, Mwanga JA, Kakuru R, Mpeirwe D,  et al.
2024-04-01 • Vaccine
2024-04-01 • Vaccine
BACKGROUND
Understanding the knowledge, perception and attitudes towards Ebola vaccines is an important factor in ensuring future use of these vaccines. A qualitative methods study e...
Journal Article
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Research

Coverage survey and lessons learned from a pre-emptive cholera vaccination campaign in urban and rural communities affected by landslides and floods in Freetown Sierra Leone

Gelormini M, Gripenberg M, Marke D, Murray MB, Yambasu S,  et al.
2023-03-03 • Vaccine
2023-03-03 • Vaccine
Background: On 14 August 2017, massive landslides and floods hit Freetown (Sierra Leone). More than 1,000 people lost their lives while approximately 6,000 people were displaced. The are...
Journal Article
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Research

Immunogenicity of rVSVΔG-ZEBOV-GP Ebola vaccine (ERVEBO®) in African clinical trial participants by age, sex, and baseline GP-ELISA titer: A post hoc analysis of three Phase 2/3 trials

Simon JK, Kennedy SB, Mahon BE, Dubey SA, Grant-Klein RJ,  et al.
2022-10-05 • Vaccine
2022-10-05 • Vaccine
BACKGROUND
ERVEBO®, a live recombinant vesicular stomatitis virus (VSV) vaccine containing the Zaire ebolavirus glycoprotein (GP) in place of the VSV GP (rVSVΔG-ZEBOV-GP), was advanc...
Journal Article
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Research

Implementation of an outbreak response vaccination campaign with typhoid conjugate vaccine – Harare, Zimbabwe, 2019

Poncin M, Marembo J, Chitando P, Sreenivasan N, Makwara I,  et al.
2022-08-02 • Vaccine
2022-08-02 • Vaccine
INTRODUCTION
Typhoid fever is a public-health problem in Harare, the capital city of Zimbabwe, with seasonal outbreaks occurring annually since 2010. In 2019, the Ministry of Health ...
Journal Article
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Research

Prevalence and factors associated with parents' non-intention to vaccinate their children and adolescents against COVID-19 in Latin America and the Caribbean

Urrunaga-Pastor D, Herrera-Anazco P, Uyen-Cateriano A, Toro-Huamanchumo CJ, Rodriguez-Morales AJ,  et al.
2021-11-09 • Vaccine
2021-11-09 • Vaccine
We aimed to estimate the prevalence and factors associated with parents' non-intention to vaccinate their children and adolescents against COVID-19 in Latin America and the Caribbean (LA...
Journal Article
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Case Report/Series

Fatal outcomes following immunization errors as reported to the EudraVigilance: A case series

Hoeve CE, Gadroen K, Kwa MSG, van Haren A, Sturkenboom MCJM,  et al.
2020-03-01 • Vaccine
2020-03-01 • Vaccine
BACKGROUND
Serious adverse reactions after immunization are rare but do occur. In very rare instances, cases with fatal outcome have been reported. These reports can have a huge impa...
Journal Article
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Research

Feasibility of a mass vaccination campaign using a two-dose oral cholera vaccine in an urban cholera-endemic setting in Mozambique

Cavailler P, Perroud V, Mcchesney M, Ampuero S, Guerin PJ,  et al.
2006-05-29 • Vaccine
2006-05-29 • Vaccine
We conducted a study to assess the feasibility and the potential vaccine coverage of a mass vaccination campaign using a two-dose oral cholera vaccine in an urban endemic neighbourhood o...
Journal Article
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Research

Effectiveness of typhoid conjugate vaccine in Zimbabwe used in response to an outbreak among children and young adults: A matched case control study

Lightowler M, Manangazira P, Nackers F, Van Herp M, Phiri I,  et al.
2022-06-09 • Vaccine
2022-06-09 • Vaccine
BACKGROUND
Zimbabwe suffers from regular outbreaks of typhoid fever (TF), worse since 2017. Most cases were in Harare and a vaccination campaign with Typhoid Conjugate Vaccine (TCV) ...
Journal Article
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Research

Vaccination coverage survey versus administrative data in the assessment of mass yellow fever immunization in internally displaced persons—Liberia, 2004

Huhn GD, Brown J, Perea W, Berthe A, Otero H,  et al.
2006-02-06 • Vaccine
2006-02-06 • Vaccine
Yellow fever (YF) is a mosquito-borne vaccine-preventable disease with high mortality. In West Africa, low population immunity increases the risk of epidemic transmission. A cluster surv...
Journal Article
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Research

Evaluation of the stability of measles vaccine out of the cold chain under extended controlled temperature conditions

Juan-Giner A, Alsalhani A, Panunzi I, Lambert V, Van Herp M,  et al.
2020-02-08 • Vaccine
2020-02-08 • Vaccine
Measles outbreaks occur periodically in remote and difficult to reach areas in countries such as the Democratic Republic of Congo. The possibility to keep measles vaccines at temperature...
Journal Article
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Research

Carriage prevalence and serotype distribution of Streptococcus pneumoniae prior to 10-valent pneumococcal vaccine introduction: a population-based cross-sectional study in South Western Uganda, 2014

Nackers F, Cohuet S, le Polain de Waroux O, Langendorf C, Nyehangane D,  et al.
2017-09-18 • Vaccine
2017-09-18 • Vaccine
BACKGROUND
Information on Streptococcus pneumoniae nasopharyngeal (NP) carriage before the pneumococcal conjugate vaccine (PCV) introduction is essential to monitor impact. The 10-va...
Journal Article
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Research

A cluster randomized non-inferiority field trial on the immunogenicity and safety of tetanus toxoid vaccine kept in controlled temperature chain compared to cold chain

Juan-Giner A, Domicent C, Langendorf C, Roper M, Baoundoh P,  et al.
2014-09-23 • Vaccine
2014-09-23 • Vaccine
In resource-poor settings, cold chain requirements present barriers for vaccine delivery. We evaluated the immunogenicity and safety of tetanus toxoid (TT) vaccine in "Controlled Tempera...
Journal Article
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Research

Humoral and cellular immune response induced by rVSVΔG-ZEBOV-GP vaccine among frontline workers during the 2013-2016 West Africa Ebola outbreak in Guinea

Juan-Giner A, Hitchings MD, Soumah A, Strecker T, Sadjo M,  et al.
2020-06-01 • Vaccine
2020-06-01 • Vaccine
Background
As part of a Phase III trial with the Ebola vaccine rVSVΔG-ZEBOV-GP in Guinea, we invited frontline workers (FLWs) to participate in a sub-study to provide additional inf...
Journal Article
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Research

Vaccination in emergencies

Paquet C
1999-10-29 • Vaccine
1999-10-29 • Vaccine
Nongovernmental organisations (NGOs) are the main actors of vaccine delivery during complex humanitarian emergencies such as large population displacements. This paper discusses the use ...
Journal Article
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Research

Biological diagnosis of meningococcal meningitis in the African meningitis belt: current epidemic strategy and new perspectives

Chanteau S, Rose AMC, Djibo S, Nato F, Boisier P
2007-09-03 • Vaccine
2007-09-03 • Vaccine
Laboratory diagnosis is an essential component in surveillance of meningococcal epidemics, as it can inform decision-makers of the Neisseria meningitidis serogroup(s) involved and the mo...
Journal Article
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Research

A mixture model to assess the the immunogenicity of an oral rotavirus vaccine among healthy infants in Niger

Hitchings MD, Cummings DAT, Grais RF, Isanaka S
2020-12-03 • Vaccine
2020-12-03 • Vaccine
Analysis of immunogenicity data is a critical component of vaccine development, providing a biological basis to support any observed protection from vaccination. Conventional methods for...
Journal Article
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Research

Factors influencing participation in an Ebola vaccine trial among frontline workers in Guinea

Grantz KH, Claudot P, Kambala M, Kouyate M, Soumah A,  et al.
2019-11-15 • Vaccine
2019-11-15 • Vaccine
BACKGROUND
Alongside the clinical aspects of the immunogenicity and safety trial of an Ebola vaccine deployed among front-line workers, a qualitative study was conducted to describe ...
Journal Article
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Research

Field challenges to measles elimination in the Democratic Republic of the Congo

Coulborn RM, Nackers F, Bachy C, Porten K, Vochten H,  et al.
2020-02-25 • Vaccine
2020-02-25 • Vaccine
BACKGROUND:
During a measles epidemic, the Ministry of Public Health (MOH) of the Democratic Republic of the Congo conducted supplementary immunization activities (2016-SIA) from Au...
Journal Article
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Commentary

Pneumococcal conjugate vaccine use during humanitarian crises

van Zandvoort K, Checchi F, Diggle E, Eggo RM, Gadroen K,  et al.
2019-10-23 • Vaccine
2019-10-23 • Vaccine
Streptococcus pneumoniae is a common human commensal that causes a sizeable part of the overall childhood mortality in low income settings. Populations affected by humanitarian crises ar...
Journal Article
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Research

Safety of a heat-stable rotavirus vaccine among children in Niger: Data from a phase 3, randomized, double-blind, placebo-controlled trial

Coldiron ME, Guindo O, Makarimi R, Soumana I, Matar Seck A,  et al.
2018-05-08 • Vaccine
2018-05-08 • Vaccine
BACKGROUND
Rotavirus remains a major cause of diarrhea among children under 5 years of age. The efficacy of RotaSIIL, a pentavalent rotavirus vaccine, was shown in an event-driven tr...