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Showing 1 - 14 of 14 Items
Showing 1 - 14 of 14 Items
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Journal Article
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Research

Evaluation of hydroxychloroquine or chloroquine for the prevention of COVID-19 (COPCOV): A double-blind, randomised, placebo-controlled trial

Schilling WHK, Mukaka M, Callery JJ, Llewelyn MJ, Cruz CV,  et al.
2024-09-12 • PLOS Medicine
2024-09-12 • PLOS Medicine

BACKGROUND

Hydroxychloroquine (HCQ) has proved ineffective in treating patients hospitalised with Coronavirus Disease 2019 (COVID-19), but uncertainty remains over its safety an...

Journal Article
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Research

Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial

Dondorp AM, Fanello CI, Hendriksen IC, Gomes E, Seni A,  et al.
2010-11-08 • Lancet
2010-11-08 • Lancet
Severe malaria is a major cause of childhood death and often the main reason for paediatric hospital admission in sub-Saharan Africa. Quinine is still the established treatment of choice...
Journal Article
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Short Report

Community participation during two mass anti-malarial administrations in Cambodia: lessons from a joint workshop

Peto TJ, Debackere M, Etienne W, Vernaeve L, Tripura R,  et al.
2018-01-27 • Malaria Journal
2018-01-27 • Malaria Journal
Two mass drug administrations (MDA) against falciparum malaria were conducted in 2015-16, one as operational research in northern Cambodia, and the other as a clinical trial in western C...
Journal Article
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Review

Novel Approaches to Control Malaria in Forested Areas of Southeast Asia

von Seidlein L, Peto TJ, Tripura R, Pell C, Yeung S,  et al.
2019-05-07
2019-05-07
The emergence and spread of drug resistance in the Greater Mekong Subregion (GMS) have added urgency to accelerate malaria elimination while reducing the treatment options. The remaining...
Journal Article
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Commentary

The value of and challenges for cholera vaccines in Africa

von Seidlein L, Jiddawi MS, Grais RF, Luquero FJ, Lucas M,  et al.
2013-11-01 • Journal of Infectious Diseases
2013-11-01 • Journal of Infectious Diseases
The 21st century saw a shift in the cholera burden from Asia to Africa. The risk factors for cholera outbreaks in Africa are incompletely understood, and the traditional emphasis on prov...
Journal Article
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Research

Development of weight and age-based dosing of daily primaquine for radical cure of vivax malaria

Taylor WRJ, Hoglund RM, Peerawaranun P, Nguyen TN, Hien TT,  et al.
2021-09-09 • Malaria Journal
2021-09-09 • Malaria Journal
BACKGROUND
In many endemic areas, Plasmodium vivax malaria is predominantly a disease of young adults and children. International recommendations for radical cure recommend fixed tar...
Journal Article
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Research

A look back at an ongoing problem: Shigella dysenteriae type 1 epidemics in refugee settings in Central Africa (1993-1995)

Kerneis S, Guerin PJ, von Seidlein L, Legros D, Grais RF
2009-02-13 • PLOS One
2009-02-13 • PLOS One
BACKGROUND: Shigella dysenteriae type 1 (Sd1) is a cause of major dysentery outbreaks, particularly among children and displaced populations in tropical countries. Although outbreaks con...
Journal Article
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Commentary

Seasonal malaria chemoprevention: successes and missed opportunities

Coldiron ME, von Seidlein L, Grais RF
2017-11-28 • Malaria Journal
2017-11-28 • Malaria Journal
Seasonal malaria chemoprevention (SMC) was recommended in 2012 for young children in the Sahel during the peak malaria transmission season. Children are given a single dose of sulfadoxin...
Journal Article
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Research

Quantification of glucose-6-phosphate dehydrogenase activity by spectrophotometry: A systematic review and meta-analysis

Pfeffer DA, Ley B, Howes RE, Adu P, Alam MS,  et al.
2020-05-14 • PLOS Medicine
2020-05-14 • PLOS Medicine

BACKGROUND

The...

Journal Article
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Commentary

Public Health. The cholera crisis in Africa

Bhattacharya S, Black RE, Bourgeois L, Clemens JD, Cravioto A,  et al.
2009-05-14 • Science
2009-05-14 • Science
Journal Article
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Research

Immunogenicity and protection from a single dose of internationally available killed oral cholera vaccine: a systematic review and meta-analysis

Lopez AMZ, Deen JL, Azman AS, Luguero FJ, Kanungo S,  et al.
2017-11-21 • Clinical Infectious Diseases
2017-11-21 • Clinical Infectious Diseases
In addition to improved water supply and sanitation, the two-dose killed oral cholera vaccine (OCV) is an important tool for the prevention and control of cholera. We aimed to document t...
Journal Article
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Research

The case for reactive mass oral cholera vaccinations

Reyburn R, Deen JL, Grais RF, Bhattacharya S, Sur D,  et al.
2011-01-25 • PLOS Neglected Tropical Diseases
2011-01-25 • PLOS Neglected Tropical Diseases
The outbreak of cholera in Zimbabwe intensified interest in the control and prevention of cholera. While there is agreement that safe water, sanitation, and personal hygiene are ideal fo...
Journal Article
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Commentary

Progress in Medicine: Experts Take Stock

Beck A, Birney E, Graeber M, Tumwine J, Hay P,  et al.
2015-12-29 • PLOS Medicine
2015-12-29 • PLOS Medicine
Journal Article
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Research

The scenario approach for countries considering the addition of oral cholera vaccination in cholera preparedness and control plans

Deen JL, von Seidlein L, Luquero FJ, Troeger C, Reyburn R,  et al.
2016-01-01 • Lancet Infectious Diseases
2016-01-01 • Lancet Infectious Diseases
Oral cholera vaccination could be deployed in a diverse range of situations from cholera-endemic areas and locations of humanitarian crises, but no clear consensus exists. The supply of ...