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Copyright © Médecins Sans Frontières
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Showing 1 - 20 of 58 Items
Showing 1 - 20 of 58 Items
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Journal Article
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Research

Short oral regimens for pulmonary rifampicin-resistant tuberculosis (TB-PRACTECAL): an open-label, randomised, controlled, phase 2B-3, multi-arm, multicentre, non-inferiority trial

Nyang'wa BT, Berry C, Kazounis E, Motta I, Parpieva N,  et al.
2024-02-01 • Lancet Respiratory Medicine
2024-02-01 • Lancet Respiratory Medicine
BACKGROUND
Around 500,000 people worldwide develop rifampicin-resistant tuberculosis each year. The proportion of successful treatment outcomes remains low and new treatments are nee...
Journal Article
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Research

Standards for clinical trials for treating TB

du Cros PAK, Greig J, Cross GB, Cousins C, Berry C,  et al.
2023-12-01 • International Journal of Tuberculosis and Lung Disease
2023-12-01 • International Journal of Tuberculosis and Lung Disease
BACKGROUND
The value, speed of completion and robustness of the evidence generated by TB treatment trials could be improved by implementing standards for best practice.

METH...
Journal Article
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Research

Detection of Mycobacterium tuberculosis complex using the Xpert MTB/RIF Ultra assay on the stool of pediatric patients in Dushanbe, Tajikistan

Rekart ML, Mun L, Aung A, Gomez D, Mulanda WK,  et al.
2023-01-09 • Microbiology Spectrum
2023-01-09 • Microbiology Spectrum
We report the findings of a prospective laboratory diagnostic accuracy study to evaluate the sensitivity, specificity, and predictive values of the Xpert MTB/RIF Ultra assay for Mycobact...
MSF Ethics Review Board
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Standardized survey templates

MSF ERB Enquête rétrospective sur la mortalité

Gerstl S, Grandesso F, Siddiqui R, Greig J, du Cros PAK,  et al.
2022-10-25
2022-10-25
Ce modèle doit être utilisé comme cadre pour écrire votre protocole d'enquête de mortalité contextualisée. Il a été pré-approuvé par le comité de révision éthique de MSF le 12 juillet 20...
MSF Ethics Review Board
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Standardized survey templates

Standardised mortality surveys

Grandesso F, Gerstl S, Siddiqui R, Greig J, du Cros PAK,  et al.
2022-10-25
2022-10-25
Mortality Survey Protocol - standardised, MSF ERB approved, intersectional

This collection of files includes an overview of the whole process of conducting a mortality survey an...
Journal Article
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Letter

Revised definitions of multidrug-resistant tuberculosis treatment outcomes: closer to the reality?

Bastard M, Bonnet MMB, du Cros PAK, Khamraev AK, Hayrapetyan A,  et al.
2015-02-01 • American Journal of Respiratory and Critical Care Medicine
2015-02-01 • American Journal of Respiratory and Critical Care Medicine
Journal Article
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Commentary

Generating evidence to improve the response to neglected diseases: how operational research in a Médecins Sans Frontières Buruli ulcer treatment programme informed international management guidance

O'Brien DP, Ford NP, Vitoria M, Asiedu K, Calmy A,  et al.
2015-11-12 • PLOS Neglected Tropical Diseases
2015-11-12 • PLOS Neglected Tropical Diseases
MSF Ethics Review Board
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Standardized survey templates

Standardised vaccination coverage surveys

Gerstl S, Siddiqui R, Greig J, Lenglet AD, du Cros PAK,  et al.
2017-08-24
2017-08-24
Vaccination coverage survey protocol - standardised, MSF ERB approved, intersectional

This collection of files includes an overview of the whole process of conducting a vaccinat...
Journal Article
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Research

Peripheral Neuropathy in a Diabetic Child Treated with Linezolid for Multidrug-Resistant Tuberculosis: A Case Report and Review of the Literature

Swaminathan A, du Cros PAK, Seddon JA, Mirgayosieva S, Asladdin R,  et al.
2017-06-12 • BMC Infectious Diseases
2017-06-12 • BMC Infectious Diseases
Extensively drug-resistant (XDR) tuberculosis (TB) and multidrug resistant (MDR)-TB with additional resistance to injectable agents or fluoroquinolones are challenging to treat due to la...
Journal Article
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Research

"I Can Also Serve as an Inspiration": A Qualitative Study of the TB&Me Blogging Experience and Its Role in MDR-TB Treatment

Horter SCB, Stringer B, Venis S, du Cros PAK
2014-09-24 • PLOS One
2014-09-24 • PLOS One
In 2011, Médecins Sans Frontières (MSF) established a blogging project, "TB&Me," to enable patients with multidrug-resistant tuberculosis (MDR-TB) to share their experiences. By Septembe...
Journal Article
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Research

Hepatitis C seroprevalence and HIV co-infection in sub-Saharan Africa: a systematic review and meta-analysis

Rao VB, Johari N, du Cros PAK, Messina J, Ford NP,  et al.
2015-05-05 • Lancet Infectious Diseases
2015-05-05 • Lancet Infectious Diseases
An estimated 150 million people worldwide are infected with hepatitis C virus (HCV). HIV co-infection accelerates the progression of HCV and represents a major public health challenge. W...
Journal Article
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Commentary

Expanding access to treatment for hepatitis C in resource-limited settings: Lessons from HIV/AIDS

Ford NP, Singh K, Cooke GS, Mills EJ, von Schoen-Angerer T,  et al.
2012-03-19 • Clinical Infectious Diseases
2012-03-19 • Clinical Infectious Diseases
Research & Publication Guidance
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Guidelines/How-Tos

Randomised controlled trials: how to do them in MSF

McConnell R, Roll S, van der Kam S, Shanks L, Venis S,  et al.
2012-02-01
2012-02-01
Journal Article
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Research

Standardised shorter regimens versus individualised longer regimens for rifampin- or multidrug-resistant tuberculosis

Abidi S, Achar J, Assao Neino MM, Bang D, Benedetti A,  et al.
2020-03-20 • European Respiratory Journal
2020-03-20 • European Respiratory Journal
We sought to compare the effectiveness of two World Health Organization (WHO)-recommended regimens for the treatment of rifampin- or multidrug-resistant (RR/MDR) tuberculosis (TB): a sta...
Journal Article
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Commentary

The 'frozen state' of drug-resistant tuberculosis: notes from the field in Abkhazia

Majumdar S, O'Brien DP, Hurtado N, Hewison CCH, du Cros PAK
2011-12-08 • Internal Medicine Journal
2011-12-08 • Internal Medicine Journal
Journal Article
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Research

A case report of a child with probable drug resistant tuberculous pericarditis with a review of challenges involved in diagnosis, treatment and follow up of children with DR-TB pericarditis

Swaminathan A, du Cros PAK, Achar J, Kliescikova J, Mirgayosieva S,  et al.
2020-04-22 • BMC Infectious Diseases
2020-04-22 • BMC Infectious Diseases
Background: There are unique challenges in the diagnosis and management of multi drug resistant tuberculosis (MDR-TB) in children. It is difficult to obtain confirmatory microbiological ...
Conference Material
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Abstract

Estimation of SARS-CoV-2 infections and deaths among Rohingya refugees, Kutupalong-Balukhali camps, Bangladesh

Truelove SA, Hedge S, Kostandova N, Niehaus L, Rao B,  et al.
2021-05-18 • MSF Scientific Days International 2021: Research
2021-05-18 • MSF Scientific Days International 2021: Research
INTRODUCTION
Since the emergence of the COVID-19 pandemic, concerns have arisen regarding the potential impact of outbreaks affecting Rohingya refugees living in the Kutupalong-Baluk...
Journal Article
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Commentary

Viral hepatitis and the global burden of disease: a need to regroup

Lemoine M, Thursz M, Gore C, Swan T, Kamarulzaman A,  et al.
2013-08-05 • Journal of Viral Hepatitis
2013-08-05 • Journal of Viral Hepatitis
Journal Article
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Research

Outcomes of HIV-infected versus HIV-non-infected patients treated for drug-resistance tuberculosis: Multicenter cohort study

Bastard M, Sanchez-Padilla E, du Cros PAK, Khamraev AK, Parpieva N,  et al.
2018-03-08 • PLOS One
2018-03-08 • PLOS One
The emergence of resistance to anti-tuberculosis (DR-TB) drugs and the HIV epidemic represent a serious threat for reducing the global burden of TB. Although data on HIV-negative DR-TB t...
Journal Article
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Research

'They prefer hidden treatment': anti-tuberculosis drug-taking practices and drug regulation in Karakalpakstan

Stringer B, Lowton K, Tillashaikhov M, Parpieva N, Ulmasova D,  et al.
2016-08-01 • International Journal of Tuberculosis and Lung Disease
2016-08-01 • International Journal of Tuberculosis and Lung Disease
SETTING
The joint Médecins Sans Frontières/Ministry of Health Multidrug-Resistant Tuberculosis (MDR-TB) Programme, Karakalpakstan, Uzbekistan.

OBJECTIVE
Uzbekistan has h...