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Copyright © Médecins Sans Frontières
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Showing 1 - 20 of 47 Items
Showing 1 - 20 of 47 Items
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Journal Article
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Research

Changes over time in the proportion of advanced HIV disease in two high HIV prevalence settings in Ndhiwa (Kenya) and Eshowe (South Africa)

Chihana M, Conan N, Ohler L, Huerga H, Wanjala S,  et al.
2024-06-17 • Journal of the International Association of Providers of AIDS Care
2024-06-17 • Journal of the International Association of Providers of AIDS Care
BACKGROUND
The burden of advanced HIV disease remains a significant concern in sub-Saharan Africa. In 2015, the World Health Organization released recommendations to treat all people...
Conference Material
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Poster

Enhancing adolescent HIV care: Implementation and evaluation of teen models-of-care for adolescents living with HIV in Uganda and Malawi

Masson D, Nicholas S, Szumilin E, Balkan S
2024-05-23 • Epicentre Scientific Day 2024
2024-05-23 • Epicentre Scientific Day 2024
Technical Report
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Study report

The design, implementation, and effectiveness of teen models of care: lessons from MSF supported programmes providing treatment and care for adolescents aged 10 to 19 living with HIV in Malawi and Uganda

Masson D, Nicolas S, Szumilin E, Balkan S
2024-05-01
2024-05-01
This “lessons learned” report presents a thorough documentation of the implementation process of the models of care for adolescents (aged ~10-19 years) living with HIV (ALHIV) in two HIV...
Technical Report
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Evidence Brief

The design, implementation, and effectiveness of teen models of care: lessons from MSF supported programmes providing treatment and care for adolescents aged 10 to 19 living with HIV in Malawi and Uganda

Masson D, Nicolas S, Szumilin E, Balkan S
2024-05-01
2024-05-01
Journal Article
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Research

Diagnostic yield of urine lipoarabinomannan and sputum tuberculosis tests in people living with HIV: a systematic review and meta-analysis of individual participant data

Broger T, Koeppel L, Huerga H, Miller P, Gupta-Wright A,  et al.
2023-06-01 • Lancet Global Health
2023-06-01 • Lancet Global Health
BACKGROUND
Sputum is the most widely used sample to diagnose active tuberculosis, but many people living with HIV are unable to produce sputum. Urine, in contrast, is readily availab...
Journal Article
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Research

Viral suppression and HIV-1 drug resistance 1 year after pragmatic transitioning to dolutegravir first-line therapy in Malawi: a prospective cohort study

Schramm B, Temfack E, Descamps D, Nicholas S, Peytavin G,  et al.
2022-08-01 • Lancet HIV
2022-08-01 • Lancet HIV
BACKGROUND
Many countries are now replacing non-nucleoside reverse transcriptase inhibitor (NNRTI)-based first-line antiretroviral therapy (ART) with a regimen containing tenofovir d...
Journal Article
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Research

Comparison of methods to correct survival estimates and survival regression analysis on a large HIV African cohort

Henriques J, Pujades M, McGuire M, Szumilin E, Iwaz J,  et al.
2012-02-23 • PLOS One
2012-02-23 • PLOS One
OBJECTIVE
The evaluation of HIV treatment programs is generally based on an estimation of survival among patients receiving antiretroviral treatment (ART). In large HIV programs, los...
Journal Article
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Research

Characteristics, medical management and outcomes of survivors of sexual gender-based violence, Nairobi, Kenya

Buard V, Van der Bergh R, Tayler-Smith K, Godia P, Sobry A,  et al.
2013-06-21 • Public Health Action
2013-06-21 • Public Health Action
SETTING
Médecins Sans Frontières Clinic for sexual gender-based violence (SGBV), Nairobi, Kenya.

OBJECTIVES
Among survivors of SGBV in 2011, to describe demographic char...
Journal Article
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Research

Highly active antiretroviral therapy in resource-poor settings: the experience of Médecins Sans Frontières

Tassie JM, Szumilin E, Calmy A, Goemaere E
2003-09-05 • AIDS
2003-09-05 • AIDS
We describe the short-term results of highly active antiretroviral therapy (HAART) in seven projects in low and middle income countries. A total of 743 adults were included, and clinical...
Journal Article
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Research

Weight gain at 3 months of antiretroviral therapy is strongly associated with survival: evidence from two developing countries

Madec Y, Szumilin E, Genevier C, Ferradini LLF, Balkan S,  et al.
2009-04-27 • AIDS
2009-04-27 • AIDS
BACKGROUND
In developing countries, access to laboratory tests remains limited, and the use of simple tools such as weight to monitor HIV-infected patients treated with antiretrovira...
Journal Article
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Research

Urine lipoarabinomannan testing for all HIV patients hospitalized in the medical wards identifies a large proportion of patients with tuberculosis at risk of death

Huerga H, Rucker SCM, Bastard M, Mpunga J, Amoros Quiles I,  et al.
2020-12-23 • Open Forum Infectious Diseases
2020-12-23 • Open Forum Infectious Diseases
BACKGROUND
Diagnosing tuberculosis (TB), the leading cause of death in people with HIV, remains a challenge in resource-limited countries. We assessed TB diagnosis using a strategy t...
Journal Article
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Research

Therapeutic Failure of Melarsoprol Among Patients Treated for Late Stage T.b. Gambiense Human African Trypanosomiasis in Uganda

Legros D, Fournier C, Gastellu-Etchegorry M, Maiso F, Szumilin E
1999-07-01 • Bulletin de la Société de Pathologie Exotique
1999-07-01 • Bulletin de la Société de Pathologie Exotique
The failure rate of melarsoprol after treatment of late stage cases of Human African Trypanosomiasis (HAT) is usually under 7%, even though the drug has been used for such treatment over...
Journal Article
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Research

Highly active antiretroviral therapy in resource-poor settings: the experience of Medecins Sans Frontieres

Tassie JM, Szumilin E, Calmy A, Goemaere E
2003-09-01 • AIDS
2003-09-01 • AIDS
We describe the short-term results of highly active antiretroviral therapy (HAART) in seven projects in low and middle income countries. A total of 743 adults were included, and clinical...
Journal Article
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Research

Timeliness of Clinic Attendance is a good predictor of Virological Response and Resistance to Antiretroviral drugs in HIV-infected patients

Bastard M, Pinoges LLP, Balkan S, Szumilin E, Ferreyra C,  et al.
2012-11-07 • PLOS One
2012-11-07 • PLOS One
Ensuring long-term adherence to therapy is essential for the success of HIV treatment. As access to viral load monitoring and genotyping is poor in resource-limited settings, a simple to...
Journal Article
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Research

Paediatric HIV care in sub-Saharan Africa: clinical presentation and 2-year outcomes stratified by age group

Ben-Farhat J, Gale M, Szumilin E, Balkan S, Poulet E,  et al.
2013-06-20 • Tropical Medicine and International Health
2013-06-20 • Tropical Medicine and International Health
To examine age differences in mortality and programme attrition amongst paediatric patients treated in four African HIV programmes.
Journal Article
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Research

Two-fold increase in the HIV viral load suppression rate along with decreased incidence over six years in Ndhiwa sub-county, Kenya

Conan N, Badawi M, Chihana ML, Wanjala S, Kingwara L,  et al.
2021-10-12 • Tropical Medicine and International Health
2021-10-12 • Tropical Medicine and International Health
BACKGROUND
HIV-positive individuals who maintain an undetectable viral load cannot transmit the virus to others. In 2012, an HIV population-based survey was conducted in Ndhiwa sub-c...
Journal Article
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Research

Diagnostic value of the urine lipoarabinomannan assay in HIV-positive, ambulatory patients with CD4 below 200 cells/μl in 2 low-resource settings: A prospective observational study.

Huerga H, Rucker SCM, Cossa L, Bastard M, Amoros I,  et al.
2019-04-30 • PLOS Medicine
2019-04-30 • PLOS Medicine
BACKGROUND:
Current guidelines recommend the use of the lateral flow urine lipoarabinomannan assay (LAM) in HIV-positive, ambulatory patients with signs and symptoms of tuberculosis...
Journal Article
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Short Report

High prevalence of NRTI and NNRTI drug resistance among ART-experienced, hospitalized inpatients

Bossard C, Schramm B, Wanjala S, Jain L, Mucinya G,  et al.
2021-04-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2021-04-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
Journal Article
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Research

Closer to 90-90-90. The Cascade of Care After 10 Years of ART Scale-Up in Rural Malawi: a Population Study

Maman D, Chilima B, Masiku C, Ayouba A, Masson S,  et al.
2016-02-15 • Journal of the International AIDS Society
2016-02-15 • Journal of the International AIDS Society
The antiretroviral therapy (ART) programme supported by Médecins Sans Frontières in the rural Malawian district of Chiradzulu was one of the first in sub-Saharan Africa to scale up ART d...
Journal Article
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Research

Retention in care among clinically stable antiretroviral therapy patients following a six-monthly clinical consultation schedule: findings from a cohort study in rural Malawi

Wringe A, Cawley C, Szumilin E, Salumu L, Amoros Quiles I,  et al.
2018-11-21 • Journal of the International AIDS Society
2018-11-21 • Journal of the International AIDS Society
Longer intervals between clinic consultations for clinically stable antiretroviral therapy (ART) patients may improve retention in care and reduce facility workload. We assessed long-ter...