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Showing 1 - 20 of 23 Items
Showing 1 - 20 of 23 Items
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Journal Article
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Letter

Is same-day antiretroviral therapy initiation beneficial? Methodological aspects when comparing observational and randomized studies

Schomaker M, Kerschberger B, Boulle A
2024-03-20 • Clinical Infectious Diseases
2024-03-20 • Clinical Infectious Diseases
Journal Article
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Research

Sustained high fatality during TB therapy amid rapid decline in TB mortality at population level: A retrospective cohort and ecological analysis from Shiselweni, Eswatini

Kerschberger B, Vambe D, Schomaker M, Mabhena E, Daka M,  et al.
2024-03-01 • Tropical Medicine and International Health
2024-03-01 • Tropical Medicine and International Health
OBJECTIVES
Despite declining TB notifications in Southern Africa, TB‐related deaths remain high. We describe patient‐ and population‐level trends in TB‐related deaths in Eswatini ove...
Journal Article
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Letter

Response to “treatment outcomes after offering same-day Initiation of human immunodeficiency virus (HIV) treatment—how to interpret discrepancies between different studies”

Schomaker M, Kerschberger B, Boulle AM
2023-08-05 • Clinical Infectious Diseases
2023-08-05 • Clinical Infectious Diseases
Protocol
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Research Protocol

Elevation and cholera: an epidemiological spatial analysis of the cholera epidemic in Harare, Zimbabwe, 2008-2009

Fernandez MAL, Schomaker M, Mason PR, Fesselet JF, Baudot Y,  et al.
2012-06-18
2012-06-18
BACKGROUND
In highly populated African urban areas where access to clean water is a challenge, water source contamination is one of the most cited risk factors in a cholera epidemic....
Journal Article
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Research

Mortality in patients with HIV-1 infection starting antiretroviral therapy in South Africa, Europe, or North America: a collaborative analysis of prospective studies

Boulle AM, Schomaker M, May MT, Hogg RS, Shepherd B,  et al.
2014-09-09 • PLOS Medicine
2014-09-09 • PLOS Medicine
BACKGROUND
High early mortality in patients with HIV-1 starting antiretroviral therapy (ART) in sub-Saharan Africa, compared to Europe and North America, is well documented. Longer-t...
Journal Article
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Research

CD4 count slope and mortality in HIV-infected patients on antiretroviral therapy: multicohort analysis from South Africa

Hoffman CJ, Schomaker M, Fox MP, Mutevedzi, Giddy J,  et al.
2013-01-22 • Journal of Acquired Immune Deficiency Syndromes (1999)
2013-01-22 • Journal of Acquired Immune Deficiency Syndromes (1999)
In many resource-limited settings monitoring of combination antiretroviral therapy (cART) is based on the current CD4 count, with limited access to HIV RNA tests or laboratory diagnostic...
Journal Article
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Research

Optimal Timing of Antiretroviral Treatment Initiation in HIV-Positive Children and Adolescents: a Multiregional Analysis from Southern Africa, West Africa and Europe

Schomaker M, Leroy V, Wolfs T, Technau KG, Renner L,  et al.
2016-06-24 • International Journal of Epidemiology
2016-06-24 • International Journal of Epidemiology
Background: There is limited knowledge about the optimal timing of antiretroviral treatment initiation in older children and adolescents. Methods: A total of 20 576 antiretroviral treatm...
Journal Article
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Research

Growth and mortality outcomes for different antiretroviral therapy initiation criteria in children aged 1-5 years: a causal modelling analysis

Schomaker M, Davies A, Malateste K, Renner L, Sawry S,  et al.
2015-10-16 • Epidemiology
2015-10-16 • Epidemiology
Journal Article
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Research

HIV programmatic outcomes following implementation of the 'Treat-All' policy in a public sector setting in Eswatini: a prospective cohort study

Kerschberger B, Schomaker M, Jobanputra K, Kabore SM, Teck R,  et al.
2020-03-03 • Journal of the International AIDS Society
2020-03-03 • Journal of the International AIDS Society
INTRODUCTION:
The Treat-All policy - antiretroviral therapy (ART) initiation irrespective of CD4 cell criteria - increases access to treatment. Many ART programmes, however, reporte...
Journal Article
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Research

Elevation and cholera: an epidemiological spatial analysis of the cholera epidemic in Harare, Zimbabwe, 2008-2009

Fernandez MAL, Schomaker M, Mason PR, Fesselet JF, Baudot Y,  et al.
2012-06-18 • BMC Public Health
2012-06-18 • BMC Public Health
BACKGROUND
In highly populated African urban areas where access to clean water is a challenge, water source contamination is one of the most cited risk factors in a cholera epidemic....
Journal Article
|
Research

Life expectancies of South African adults starting antiretroviral treatment: collaborative analysis of cohort studies

Johnson LF, Mossong J, Dorrington R, Schomaker M, Hoffman CJ,  et al.
2013-04-09 • PLOS Medicine
2013-04-09 • PLOS Medicine
Few estimates exist of the life expectancy of HIV-positive adults receiving antiretroviral treatment (ART) in low- and middle-income countries. We aimed to estimate the life expectancy o...
Journal Article
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Research

Decreased risk of HIV-associated TB during antiretroviral therapy expansion in rural Eswatini from 2009 to 2016: a cohort and population-based analysis

Kerschberger B, Schomaker M, Telnov A, Vambe D, Kisyeri N,  et al.
2019-09-19 • Tropical Medicine and International Health
2019-09-19 • Tropical Medicine and International Health
OBJECTIVES
This paper assesses patient- and population-level trends in TB notifications during rapid expansion of antiretroviral therapy in Eswatini which has an extremely high incid...
Journal Article
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Research

Programmatic outcomes and impact of rapid public sector antiretroviral therapy expansion in adults prior to introduction of the WHO treat-all approach in rural Eswatini

Kerschberger B, Schomaker M, Ciglenecki I, Pasipamire M, Mabhena E,  et al.
2019-04-01 • Tropical Medicine and International Health
2019-04-01 • Tropical Medicine and International Health
To assess long-term antiretroviral therapy (ART) outcomes during rapid HIV programme expansion in the public sector of Eswatini (formerly Swaziland). This is a retrospectively establishe...
Journal Article
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Research

Gender differences in survival among adult patients starting antiretorivral therapy in South Africa: a multicentre cohort study

Cornell M, Schomaker M, Garone DB, Giddy J, Hoffmann CJ,  et al.
2012-09-04 • PLOS Medicine
2012-09-04 • PLOS Medicine


Background: Increased mortality among men on antiretroviral therapy (ART) has been documented but remains poorly understood. We examined the magnitude of and risk factors for g...
Journal Article
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Research

Effectiveness of Patient Adherence Groups as a model of care for stable patients on Antiretroviral Therapy in Khayelitsha, Cape Town, South Africa

Luque Fernandez MA, van Cutsem G, Goemaere E, Hilderbrand K, Schomaker M,  et al.
2013-02-13 • PLOS One
2013-02-13 • PLOS One
Innovative models of care are required to cope with the ever-increasing number of patients on antiretroviral therapy in the most affected countries. This study, in Khayelitsha, South Afr...
Journal Article
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Research

Age in antiretroviral therapy programmes in South Africa: a retrospective, multicentre, observational cohort study

Cornell M, Johnson LF, Schomaker M, Tanser F, Maskew M,  et al.
2015-08-03 • Lancet HIV
2015-08-03 • Lancet HIV
BACKGROUND
As access to antiretroviral therapy (ART) expands, increasing numbers of older patients will start treatment and need specialised long-term care. However, the effect of ag...
Journal Article
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Research

Virologic response of adolescents living with perinatally acquired HIV receiving antiretroviral therapy in the period of early adolescence (10-14 years) in South Africa

Nyakato P, Schomaker M, Sipambo N, Technau KG, Fatti G,  et al.
2021-01-21 • AIDS
2021-01-21 • AIDS
Background and objectives:
Adolescents living with perinatally acquired HIV (ALPHIV) on antiretroviral therapy (ART) have been noted to have poorer adherence, retention and virolog...
Journal Article
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Research

Feasibility of antiretroviral therapy initiation under the treat‐all policy under routine conditions: a prospective cohort study from Eswatini

Kerschberger B, Jobanputra K, Schomaker M, Kabore SM, Teck R,  et al.
2019-10-01 • Journal of the International AIDS Society
2019-10-01 • Journal of the International AIDS Society
Introduction
The World Health Organization recommends the Treat‐All policy of immediate antiretroviral therapy (ART) initiation, but questions persist about its feasibility in resou...
Journal Article
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Research

The impact of same-day antiretroviral therapy initiation under the WHO treat-all policy

Kerschberger B, Boulle AM, Kuwengwa R, Ciglenecki I, Schomaker M
2021-02-12 • American Journal of Epidemiology
2021-02-12 • American Journal of Epidemiology
Rapid initiation of antiretroviral therapy (ART) is recommended for people living with HIV, with the option to start treatment on the day of diagnosis (same-day-ART). However, the effect...
Journal Article
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Research

Predicting, diagnosing, and treating acute and early HIV infection in a public sector facility in Eswatini

Kerschberger B, Aung A, Mpala Q, Ntshalintshali N, Mamba C,  et al.
2021-12-15 • Journal of Acquired Immune Deficiency Syndromes (JAIDS)
2021-12-15 • Journal of Acquired Immune Deficiency Syndromes (JAIDS)
BACKGROUND
The lack of acute and early HIV infection (AEHI) diagnosis and care contributes to high HIV incidence in resource-limited settings. We aimed to assess the yield, predict a...