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Showing 1 - 17 of 17 Items
Showing 1 - 17 of 17 Items
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Journal Article
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Letter

Revised definitions of multidrug-resistant tuberculosis treatment outcomes: closer to the reality?

Bastard M, Bonnet MMB, du Cros PAK, Khamraev AK, Hayrapetyan A,  et al.
2015-02-01 • American Journal of Respiratory and Critical Care Medicine
2015-02-01 • American Journal of Respiratory and Critical Care Medicine
Journal Article
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Research

Reasons for defaulting from drug-resistant tuberculosis treatment in Armenia: a quantitative and qualitative study

Sanchez-Padilla E, Marquer C, Kalon S, Qayyum S, Hayrapetyan A,  et al.
2014-02-01 • International Journal of Tuberculosis and Lung Disease
2014-02-01 • International Journal of Tuberculosis and Lung Disease
SETTING
Armenia, a country with a high prevalence of drug-resistant tuberculosis (DR-TB).

OBJECTIVE
To identify factors related to default from DR-TB treatment in Yereva...
Journal Article
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Research

Effects of Treatment Interruption Patterns on Treatment Success Among Patients With Multidrug-Resistant Tuberculosis in Armenia and Abkhazia

Bastard M, Sanchez-Padilla E, Hewison CCH, Hayrapetyan A, Khurkhumal S,  et al.
2014-10-13 • Journal of Infectious Diseases
2014-10-13 • Journal of Infectious Diseases
The success of the current treatment regimen for multidrug-resistant tuberculosis (MDR-TB) is poor partly due to a high defaulter rate. Many studies explored predictors of poor outcomes,...
Journal Article
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Research

High prevalence of multidrug-resistant tuberculosis, Swaziland, 2009-2010

Sanchez-Padilla E, Dlamini T, Ascorra A, Rusch-Gerdes S, Tefera ZD,  et al.
2012-01-01 • Emerging Infectious Diseases
2012-01-01 • Emerging Infectious Diseases
In Africa, although emergence of multidrug-resistant (MDR) tuberculosis (TB) represents a serious threat in countries severely affected by the HIV epidemic, most countries lack drug-resi...
Journal Article
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Research

MDR M. tuberculosis outbreak clone in Eswatini missed by Xpert has elevated bedaquiline resistance dated to the pre-treatment era

Beckert P, Sanchez-Padilla E, Merker M, Dreyer V, Kohl TA,  et al.
2020-11-25 • Genome Medicine
2020-11-25 • Genome Medicine
Background
Multidrug-resistant (MDR) Mycobacterium tuberculosis complex strains not detected by commercial molecular drug susceptibility testing (mDST) assays due to the RpoB I491F ...
Journal Article
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Research

Systematic, Point-of-Care Urine Lipoarabinomannan (Alere TB-LAM) Assay for Diagnosing Tuberculosis in Severely Immunocompromised HIV-Positive Ambulatory Patients

Huerga H, Cossa L, Manhiça I, Bastard M, Telnov A,  et al.
2020-03-05 • American Journal of Tropical Medicine and Hygiene
2020-03-05 • American Journal of Tropical Medicine and Hygiene
Point-of-care urine-lipoarabinomannan (LAM) Alere Determine TB-LAM assay has shown utility diagnosing tuberculosis (TB) in HIV-positive, severely immunocompromised, TB-symptomatic patien...
Journal Article
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Research

Diagnostic value of the urine lipoarabinomannan assay in HIV-positive, ambulatory patients with CD4 below 200 cells/μl in 2 low-resource settings: A prospective observational study.

Huerga H, Rucker SCM, Cossa L, Bastard M, Amoros I,  et al.
2019-04-30 • PLOS Medicine
2019-04-30 • PLOS Medicine
BACKGROUND:
Current guidelines recommend the use of the lateral flow urine lipoarabinomannan assay (LAM) in HIV-positive, ambulatory patients with signs and symptoms of tuberculosis...
Journal Article
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Review

Burden of disease and circulating serotypes of rotavirus infection in sub-Saharan Africa: systematic review and meta-analysis

Sanchez-Padilla E, Guerin PJ, Steele AD, Luquero FJ
2009-09-01 • Lancet Infectious Diseases
2009-09-01 • Lancet Infectious Diseases
Two new rotavirus vaccines have recently been licensed in many countries. However, their efficacy has only been shown against certain serotypes commonly circulating in Europe, North Amer...
Journal Article
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Research

Outcomes of HIV-infected versus HIV-non-infected patients treated for drug-resistance tuberculosis: Multicenter cohort study

Bastard M, Sanchez-Padilla E, du Cros PAK, Khamraev AK, Parpieva N,  et al.
2018-03-08 • PLOS One
2018-03-08 • PLOS One
The emergence of resistance to anti-tuberculosis (DR-TB) drugs and the HIV epidemic represent a serious threat for reducing the global burden of TB. Although data on HIV-negative DR-TB t...
Journal Article
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Research

High prevalence of infection and low incidence of disease in child contacts of patients with drug-resistant tuberculosis: a prospective cohort study

Huerga H, Sanchez-Padilla E, Melikyan N, Atshemyan H, Ulumyan A,  et al.
2018-12-06 • Archives of Disease in Childhood
2018-12-06 • Archives of Disease in Childhood
OBJECTIVE
We aimed to measure the prevalence and incidence of latent tuberculosis infection (LTBI) and tuberculosis (TB) disease in children in close contact with patients with drug-...
Journal Article
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Research

Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages

Stucki D, Brites D, Jeljeli L, Coscolla M, Liu Q,  et al.
2016-10-31 • Nature Genetics
2016-10-31 • Nature Genetics
Generalist and specialist species differ in the breadth of their ecological niches. Little is known about the niche width of obligate human pathogens. Here we analyzed a global collectio...
Journal Article
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Research

Evolutionary history and global spread of the Mycobacterium tuberculosis Beijing lineage

Merker M, Blin C, Mona S, Duforet-Frebourg N, Lecher S,  et al.
2015-01-19 • Nature Genetics
2015-01-19 • Nature Genetics
Mycobacterium tuberculosis strains of the Beijing lineage are globally distributed and are associated with the massive spread of multidrug-resistant (MDR) tuberculosis in Eurasia. Here w...
Journal Article
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Research

What is the best culture conversion prognostic marker for patients treated for multidrug-resistant tuberculosis?

Bastard M, Sanchez-Padilla E, Hayrapetyan A, Kimenye K, Khurkhumal S,  et al.
2019-10-01 • International Journal of Tuberculosis and Lung Disease
2019-10-01 • International Journal of Tuberculosis and Lung Disease
INTRODUCTION
Identification of good prognostic marker for tuberculosis (TB) treatment response is a necessary step on the path towards a surrogate marker to reduce TB trial duration....
Journal Article
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Research

Identification of patients who could benefit from bedaquiline or delamanid: a multisite MDR-TB cohort study

Bonnet MMB, Bastard M, du Cros PAK, Khamraev AK, Kimenye K,  et al.
2016-02-01 • International Journal of Tuberculosis and Lung Disease
2016-02-01 • International Journal of Tuberculosis and Lung Disease
BACKGROUND
The World Health Organization recommends adding bedaquiline or delamanid to multidrug-resistant tuberculosis (MDR-TB) regimens for which four effective drugs are not avail...
Journal Article
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Letter

Detection of drug-resistant tuberculosis by Xpert MTB/RIF in Swaziland

Sanchez-Padilla E, Merker M, Jochims F, Dlamini T, Kahn P,  et al.
2015-03-19 • New England Journal of Medicine
2015-03-19 • New England Journal of Medicine
Journal Article
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Research

Multidrug- and isoniazid-resistant tuberculosis in three high HIV burden African regions

Sanchez-Padilla E, Ardizzoni E, Sauvageot D, Ahoua L, Martin AIC,  et al.
2013-08-01 • International Journal of Tuberculosis and Lung Disease
2013-08-01 • International Journal of Tuberculosis and Lung Disease
Despite major progress in the surveillance of drug-resistant tuberculosis (TB), data are lacking for many low-resource countries. World Health Organization estimates of multidrug-resista...
Journal Article
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Short Report

The Colombian conflict: a description of a mental health program in the Department of Tolima

Sanchez-Padilla E, Casas G, Grais RF, Hustache S, Moro MR
2009-12-23 • Conflict and Health
2009-12-23 • Conflict and Health
Colombia has been seriously affected by an internal armed conflict for more than 40 years affecting mainly the civilian population, who is forced to displace, suffers kidnapping, extorti...