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Copyright © Médecins Sans Frontières
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Showing 1 - 5 of 5 Items
Showing 1 - 5 of 5 Items
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Journal Article
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Research

Feasibility and acceptability of using the novel urine-based FujiLAM test to detect tuberculosis: A multi-country mixed-methods study

Rucker SCM, Lissouba P, Akinyi M, Lubega AV, Stewart RC,  et al.
2022-05-01 • Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
2022-05-01 • Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
BACKGROUND
The novel urine-based FujiLAM test identifies tuberculosis in HIV-positive patients but may be challenging to use at point-of-care (POC).

OBJECTIVES
We assess...
Journal Article
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Research

Urine lipoarabinomannan testing for all HIV patients hospitalized in the medical wards identifies a large proportion of patients with tuberculosis at risk of death

Huerga H, Rucker SCM, Bastard M, Mpunga J, Amoros Quiles I,  et al.
2020-12-23 • Open Forum Infectious Diseases
2020-12-23 • Open Forum Infectious Diseases
BACKGROUND
Diagnosing tuberculosis (TB), the leading cause of death in people with HIV, remains a challenge in resource-limited countries. We assessed TB diagnosis using a strategy t...
Journal Article
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Research

Diagnostic value of the urine lipoarabinomannan assay in HIV-positive, ambulatory patients with CD4 below 200 cells/μl in 2 low-resource settings: A prospective observational study.

Huerga H, Rucker SCM, Cossa L, Bastard M, Amoros I,  et al.
2019-04-30 • PLOS Medicine
2019-04-30 • PLOS Medicine
BACKGROUND:
Current guidelines recommend the use of the lateral flow urine lipoarabinomannan assay (LAM) in HIV-positive, ambulatory patients with signs and symptoms of tuberculosis...
Journal Article
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Research

Should urine-LAM tests be used in TB symptomatic HIV-positive patients when no CD4 count is available? A prospective observational cohort study from Malawi

Huerga H, Rucker SCM, Bastard M, Dimba A, Kamba C,  et al.
2020-01-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2020-01-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
Background: Current eligibility criteria for urine lateral-flow-lipoarabinomannan assay (LF-LAM) in ambulatory, HIV-positive patients rely on the CD4 count. We investigated the diagnosti...
Journal Article
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Research

Diagnostic accuracy of WHO screening criteria to guide lateral-flow lipoarabinomannan testing among HIV-positive inpatients: a systematic review and individual participant data meta-analysis

Dhana A, Hamada Y, Kengne AP, Kerkhoff AD, Broger T,  et al.
2022-05-16 • Journal of Infection
2022-05-16 • Journal of Infection
BACKGROUND
WHO recommends urine lateral-flow lipoarabinomannan (LF-LAM) testing with AlereLAM in HIV-positive inpatients only if screening criteria are met. We assessed the performan...