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Showing 1 - 16 of 16 Items
Showing 1 - 16 of 16 Items
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Journal Article
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Commentary

A call to bridge the diagnostic gap: diagnostic solutions for neonatal sepsis in low- and middle-income countries

Gleeson B, Ferreyra C, Palamountain K, Jacob ST, Spotswood N,  et al.
2024-09-10 • BMJ Global Health
2024-09-10 • BMJ Global Health
Journal Article
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Research

Viraemic-time predicts mortality among people living with HIV on second-line antiretroviral treatment in Myanmar: A retrospective cohort study

Mesic A, Decroo T, Mar HT, Jacobs BKM, Thandar MP,  et al.
2022-07-29 • PLOS One
2022-07-29 • PLOS One
INTRODUCTION
Despite HIV viral load (VL) monitoring being serial, most studies use a cross-sectional design to evaluate the virological status of a cohort. The objective of our study...
Journal Article
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Research

Errors generated by a point-of-care CD4+ T-lymphocyte analyser: a retrospective observational study in nine countries

Fajardo E, Metcalf CJ, Piriou E, Gueguen M, Maman D,  et al.
2015-06-25 • Bulletin of the World Health Organization
2015-06-25 • Bulletin of the World Health Organization
OBJECTIVE
To estimate the proportion of invalid results generated by a CD4+ T-lymphocyte analyser used by Médecins Sans Frontières (MSF) in field projects and identify factors associ...
Protocol
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Research Protocol

Survey of Plasmodium falciparum sulfadoxine/pyrimethamine (SP) resistance markers in MSF projects in North and South Kivu, DR Congo

de Wit MBK, Rao B, Lassovski M, Ouabo A, Badjo C,  et al.
2018-07-01
2018-07-01
Primary Objective: To measure the prevalence of molecular markers of SP resistant malaria in North and South Kivu, DRC.

Sulfadoxine/pyrimethamine (SP) forms the backbone of mos...
Journal Article
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Research

Suppression of circulating IgD+CD27+ memory B cells in infants living in a malaria-endemic region of Kenya

Asito AS, Piriou E, Jura WGZO, Ouma C, Odada PS,  et al.
2011-12-13 • Malaria Journal
2011-12-13 • Malaria Journal
BACKGROUND
Plasmodium falciparum infection leads to alterations in B cell subset distribution. During infancy, development of peripheral B cell subsets is also occurring. However, it...
Journal Article
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Research

Modeling of EBV Infection and Antibody Responses in Kenyan Infants with Different Levels of Malaria Exposure Shows Maternal Antibody Decay is a Major Determinant of Early EBV Infection

Reynaldi A, Schlub TE, Piriou E, Ogolla S, Sumba OP,  et al.
2016-08-28 • Journal of Infectious Diseases
2016-08-28 • Journal of Infectious Diseases
The combination of Epstein-Barr virus (EBV) infection and high malaria exposure are risk factors for endemic Burkitt lymphoma, and evidence suggests that infants in regions of high malar...
Journal Article
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Research

In vivo efficacy of artesunate-amodiaquine and artemether-lumefantrine for the treatment of uncomplicated falciparum malaria: an open-randomized, non-inferiority clinical trial in South Kivu, Democratic Republic of Congo

de Wit MBK, Funk A, Moussally K, Nkuba DA, Siddiqui R,  et al.
2016-09-06 • Malaria Journal
2016-09-06 • Malaria Journal
BACKGROUND
Between 2009 and 2012, malaria cases diagnosed in a Médecins sans Frontières programme have increased fivefold in Baraka, South Kivu, Democratic Republic of the Congo (DRC...
Journal Article
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Research

Accounting for false positive HIV tests: Is visceral leishmaniasis responsible?

Shanks L, Ritmeijer KKD, Piriou E, Siddiqui MR, Kliescikova J,  et al.
2015-07-10 • PLOS One
2015-07-10 • PLOS One
Co-infection with HIV and visceral leishmaniasis is an important consideration in treatment of either disease in endemic areas. Diagnosis of HIV in resource-limited settings relies on ra...
Journal Article
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Research

Predictors of virological failure among people living with HIV receiving first line antiretroviral treatment in Myanmar: retrospective cohort analysis

Mesic A, Spina A, Mar HT, Thit P, Decroo T,  et al.
2021-04-21 • AIDS Research and Therapy
2021-04-21 • AIDS Research and Therapy
Abstract
Background
Progress toward the global target for 95% virological supp...
Journal Article
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Research

Variation in specificity of HIV rapid diagnostic tests over place and time: an analysis of discordancy data using a Bayesian approach

Klarkowiski D, Glass K, O'Brien DP, Lokuge K, Piriou E,  et al.
2013-11-25 • PLOS One
2013-11-25 • PLOS One
BACKGROUND
Recent trends to earlier access to anti-retroviral treatment underline the importance of accurate HIV diagnosis. The WHO HIV testing strategy recommends the use of two or ...
Journal Article
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Research

Feasibility of Xpert Ebola Assay in Médecins Sans Frontières Ebola Program, Guinea

Van der Bergh R, Chaillet P, Sow MS, Amand M, van Vyve C,  et al.
2016-02-01 • Emerging Infectious Diseases
2016-02-01 • Emerging Infectious Diseases
Rapid diagnostic methods are essential in control of Ebola outbreaks and lead to timely isolation of cases and improved epidemiologic surveillance. Diagnosis during Ebola outbreaks in We...
Journal Article
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Letter

ReEBOV Antigen Rapid Test for Ebola

Piriou E, chua AC, Sprecher A
2015-12-05 • Lancet
2015-12-05 • Lancet
Journal Blog
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Perspective

Swapping production of malaria tests for covid-19 tests requires an urgent response

Chua AC, Piriou E, Tran E, de Smet M, Henkens M
2020-07-02
2020-07-02
Journal Article
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Research

Clinical diagnostic evaluation of HRP2 and pLDH-based rapid diagnostic tests for malaria in an area receiving seasonal malaria chemoprevention in Niger

Coldiron ME, Assao B, Langendorf C, Sayinzoga-Makombe N, Ciglenecki I,  et al.
2019-12-26 • Malaria Journal
2019-12-26 • Malaria Journal
BACKGROUND
Rapid diagnostic tests (RDT) for malaria are common, but their performance varies. Tests using histidine-rich protein 2 (HRP2) antigen are most common, and many have high ...
Journal Article
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Research

Markers of sulfadoxine–pyrimethamine resistance in Eastern Democratic Republic of Congo; implications for malaria chemoprevention

van Lenthe M, van der Meulen R, Lassovsky M, Ouabo A, Bakula E,  et al.
2019-12-18 • Malaria Journal
2019-12-18 • Malaria Journal
BACKGROUND
Sulfadoxine–pyrimethamine (SP) is a cornerstone of malaria chemoprophylaxis and is considered for programmes in the Democratic Republic of Congo (DRC). However, SP efficac...
Journal Article
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Research

Dilution Testing Using Rapid Diagnostic Tests in a HIV Diagnostic Algorithm: a Novel Alternative for Confirmation Testing in Resource Limited Settings

Shanks L, Siddiqui MR, Abebe A, Piriou E, Pearce N,  et al.
2015-05-14 • Virology Journal
2015-05-14 • Virology Journal
Current WHO testing guidelines for resource limited settings diagnose HIV on the basis of screening tests without a confirmation test due to cost constraints. This leads to a potential r...