logo
Science Portal
Copyright © Médecins Sans Frontières
v2.1.5209.produseast1
About MSF Science Portal
About
Contact Us
Frequently Asked Questions (FAQs)
Privacy Policy
Terms of Use
Copyright © Médecins Sans Frontières
v2.1.5209.produseast1
Showing 1 - 13 of 13 Items
Showing 1 - 13 of 13 Items
Sort By: Relevance
  • Newest to oldest
  • Oldest to newest
  • Relevance
Journal Article
|
Research

Performance of a Histidine-Rich Protein 2 Rapid Diagnostic Test, Paracheck Pf(R), for Detection of Malaria Infections in Ugandan Pregnant Women

Dhorda M, Piola P, Nyehangane D, Tumwebaze B, Nalusaji A,  et al.
2012-01-01 • PLOS One
2012-01-01 • PLOS One
Abstract. Improved laboratory diagnosis is critical to reduce the burden of malaria in pregnancy. Peripheral blood smears appear less sensitive than Plasmodium falciparum histidine-rich ...
Journal Article
|
Research

Artemether-lumefantrine to treat malaria in pregnancy is associated with reduced placental haemozoin deposition compared to quinine in a randomized controlled trial

Muehlenbachs A, Nabasumba C, McGready R, Turyakira E, Tumwebaze B,  et al.
2012-05-03 • Malaria Journal
2012-05-03 • Malaria Journal
BACKGROUND
Data on efficacy of artemisinin-based combination therapy (ACT) to treat Plasmodium falciparum during pregnancy in sub-Saharan Africa is scarce. A recent open label, rando...
Journal Article
|
Research

Glucose-6-phosphate dehydrogenase deficiency, chlorproguanil-dapsone with artesunate and post-treatment haemolysis in African children treated for uncomplicated malaria

Van Malderen C, Van Geertruyden JP, Machevo S, Gonzalez R, Bassat Q,  et al.
2012-04-30 • Malaria Journal
2012-04-30 • Malaria Journal
BACKGROUND
Malaria is a leading cause of mortality, particularly in sub-Saharan African children. Prompt and efficacious treatment is important as patients may progress within a few ...
Journal Article
|
Research

Heterogeneous decrease in malaria prevalence in children over a six-year period in south-western Uganda

De Beaudrap P, Nabasumba C, Grandesso F, Turyakira E, Schramm B,  et al.
2011-05-18 • Malaria Journal
2011-05-18 • Malaria Journal
BACKGROUND
Malaria is a major public health problem, especially for children. However, recent reports suggest a decline in the malaria burden. The aim of this study was to assess the...
Journal Article
|
Research

Paediatric pharmacovigilance: use of pharmacovigilance data mining algorithms for signal detection in a safety dataset of a paediatric clinical study conducted in seven african countries

Kajungu DK, Erhart A, Talisuna AO, Bassat Q, Karema C,  et al.
2014-05-01 • PLOS One
2014-05-01 • PLOS One
Pharmacovigilance programmes monitor and help ensuring the safe use of medicines which is critical to the success of public health programmes. The commonest method used for discovering p...
Journal Article
|
Research

Immunogenicity of fractional doses of tetravalent A/C/Y/W135 meningococcal polysaccharide vaccine: Results from a randomized non-inferiority controlled trial in Uganda

Guerin PJ, Naess LM, Fogg C, Rosenqvist E, Pinoges LLP,  et al.
2008-12-02 • PLOS Neglected Tropical Diseases
2008-12-02 • PLOS Neglected Tropical Diseases
BACKGROUND: Neisseria meningitidis serogroup A is the main causative pathogen of meningitis epidemics in sub-Saharan Africa. In recent years, serogroup W135 has also been the cause of ep...
Journal Article
|
Research

Assessment of three new parasite lactate dehydrogenase (pan-pLDH) tests for diagnosis of uncomplicated malaria

Fogg C, Twesigye R, Batwala V, Piola P, Nabasumba C,  et al.
2008-01-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
2008-01-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene
A study to assess the diagnostic capabilities of three parasite lactate dehydrogenase (pan-pLDH) tests, Vistapan), Carestart and Parabank), was conducted in Uganda. An HRP2 test, Parache...
Journal Article
|
Research

Impact of malaria during pregnancy on pregnancy outcomes in a Ugandan prospective cohort with intensive malaria screening and prompt treatment

De Beaudrap P, Turyakira E, White LJ, Nabasumba C, Tumwebaze B,  et al.
2013-04-24 • Malaria Journal
2013-04-24 • Malaria Journal
BACKGROUND
Malaria in pregnancy (MiP) is a major public health problem in endemic areas of sub-Saharan Africa and has important consequences on birth outcome. Because MiP is a comple...
Journal Article
|
Research

Efficacy and safety of artemether-lumefantrine compared with quinine in pregnant women with uncomplicated Plasmodium falciparum malaria: an open-label, randomised, non-inferiority trial

Piola P, Nabasumba C, Turyakira E, Dhorda M, Lindegardh N,  et al.
2010-11-01 • Lancet Infectious Diseases
2010-11-01 • Lancet Infectious Diseases
BACKGROUND: Malaria in pregnancy is associated with maternal and fetal morbidity and mortality. In 2006, WHO recommended use of artemisinin-based combination treatments during the second...
Journal Article
|
Research

Performance and time to become negative after treatment of three malaria rapid diagnostic tests in low and high malaria transmission settings

Grandesso F, Nabasumba C, Nyehangane D, Page AL, Bastard M,  et al.
2016-10-04 • Malaria Journal
2016-10-04 • Malaria Journal
BACKGROUND
The performance of different malaria rapid diagnostic tests (RDT) may be influenced by transmission intensity and by the length of time each test requires to become negati...
Journal Article
|
Research

Dihydroartemisinin-piperaquine and artemether-lumefantrine for treating uncomplicated malaria in African children: a randomised, non-inferiority trial

Bassat Q, Mulenga M, Tinto H, Piola P, Borrmann S,  et al.
2009-11-17 • PLOS One
2009-11-17 • PLOS One
BACKGROUND: Artemisinin combination therapies (ACTs) are currently the preferred option for treating uncomplicated malaria. Dihydroartemisinin-piperaquine (DHA-PQP) is a promising fixed-...
Journal Article
|
Research

Early biting and insecticide resistance in the malaria vector Anopheles might compromise the effectiveness of vector control intervention in Southwestern Uganda

Ojuka P, Boum Y II, Denoeud-Ndam L, Nabasumba C, Muller Y,  et al.
2015-04-09 • Malaria Journal
2015-04-09 • Malaria Journal
BACKGROUND
Southwestern Uganda has high malaria heterogeneity despite moderate vector control and other interventions. Moreover, the early biting transmission and increased resistanc...
Journal Article
|
Research

Timing of malaria in pregnancy and impact on infant growth and morbidity: A cohort study in Uganda

De Beaudrap P, Turyakira E, Nabasumba C, Tumwebaze B, Piola P,  et al.
2016-02-16 • Malaria Journal
2016-02-16 • Malaria Journal
BACKGROUND
Malaria in pregnancy (MiP) is a major cause of fetal growth restriction and low birth weight in endemic areas of sub-Saharan Africa. Understanding of the impact of MiP on ...