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Showing 1 - 16 of 16 Items
Showing 1 - 16 of 16 Items
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Research

End of treatment and 12-month post-treatment outcomes in patients treated with all-oral regimens for rifampicin-resistant tuberculosis in Ukraine: a prospective cohort study

Fardhdiani V, Trush O, Lytvynenko N, Pylypchuk S, Terleeva Y,  et al.
2025-05-23 • PLOS Global Public Health
2025-05-23 • PLOS Global Public Health

The World Health Organization has called for operational research on all-oral shorter regimens for rifampin-resistant and multidrug-resistant forms of tuberculosis (RR/MDR-TB). We fol...

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Enhancing tuberculosis (TB) case detection among hospitalized patients through lay health worker led screening: a before-and-after study in KwaZulu-Natal, South Africa

Bulti AB, Dumicho AY, Shigayeva A, Van Cutsem G, Steele SJ,  et al.
2025-04-23 • Scientific Reports
2025-04-23 • Scientific Reports

Tuberculosis (TB) among hospitalized patients is underdiagnosed. This study assessed systematic TB-screenin...

Enhancing tuberculosis (TB) diagnosis among hospitalized patients in KwaZulu-Natal, South Africa: a before-and-after study of a lay health worker-driven intervention

Bulti AB, Dumicho AY, Shigayeva A, van Cutsem G, Steele SJ,  et al.
2024-03-08 • Scientific Reports
2024-03-08 • Scientific Reports

BACKGROUND 

Tuberculosis (TB) among hospitalized patients is underdiagnosed. This study assessed systematic TB-screen...

Suicidal ideation and attempt among school going adolescents in Bhutan – a secondary analysis of a global school-based student health survey in Bhutan 2016

Dema T, Tripathy JP, Thinley S, Rani M, Dhendup T,  et al.
2019-12-02 • BMC Public Health
2019-12-02 • BMC Public Health
Suicide is one of the leading causes of death and Disability Adjusted Life Years (DALYs) worldwide. The economic, emotional and human cost of suicidal behaviour to individuals, families,...

Surgical interventions for pulmonary tuberculosis in Mumbai, India: Surgical outcomes and programmatic challenges India: surgical outcomes and programmatic challenges

Shirodkar S, Anande L, Dalal A, Desai C, Correa G,  et al.
2016-09-21 • Public Health Action
2016-09-21 • Public Health Action
SETTING
While surgery for pulmonary tuberculosis (PTB) is considered an important adjunct for specific cases, including drug-resistant tuberculosis, operational evidence on its feasi...

Psychiatric comorbidities among patients with complex drug-resistant tuberculosis in Mumbai, India

Laxmeshwar C, Das M, Mathur T, Israni T, Jha S,  et al.
2022-02-11 • PLOS One
2022-02-11 • PLOS One
BACKGROUND
People with drug-resistant tuberculosis (DR-TB) are known to suffer from many mental-health disorders. This study aims to describe the proportion of patients diagnosed wit...

Acceptability of unsupervised peer-based distribution of HIV oral self-testing for the hard-to-reach in rural KwaZulu Natal, South Africa: results from a demonstration study

Kitenge M, Laxmeshwar C, Bermudez-Aza EH, Ford-Kamara E, van Custem G,  et al.
2022-03-30 • PLOS One
2022-03-30 • PLOS One
BACKGROUND
Innovative models to distribute oral HIV self-tests (HIVST) provide an opportunity to increase access to HIV testing, especially for hard-to-reach populations. This study ...

Early safety and efficacy of the combination of bedaquiline and delamanid for the treatment of patients with drug-resistant tuberculosis in Armenia, India, and South Africa: a retrospective cohort study

Ferlazzo G, Mohr E, Laxmeshwar C, Hewison CCH, Hughes J,  et al.
2018-02-13 • Lancet Infectious Diseases
2018-02-13 • Lancet Infectious Diseases
BACKGROUND
Bedaquiline and delamanid have been approved for treatment of multidrug-resistant (MDR) tuberculosis in the past 5 years. Because of theoretical safety concerns, patients ...

Preparedness of outpatient health facilities for ambulatory treatment with all-oral short DR-TB treatment regimens in Zhytomyr, Ukraine: a cross-sectional study

Gils T, Laxmeshwar C, Duka M, Malakyan K, Siomak OV,  et al.
2020-09-21 • BMC Health Services Research
2020-09-21 • BMC Health Services Research
BACKGROUND
Ukraine has a high burden of drug-resistant tuberculosis (DR-TB). Mental health problems, including alcohol use disorder, are common co-morbidities. One in five DR-TB pati...

Routine viral load monitoring and enhanced adherence counselling at a public ART centre in Mumbai, India

Laxmeshwar C, Acharya S, Das M, Keskar P, Pazare A,  et al.
2020-05-05 • PLOS One
2020-05-05 • PLOS One
BACKGROUND
Routine viral-load (VL) measurements along with enhanced adherence counselling (EAC) are recommended to achieve virological suppression among people living with HIV/AIDS (...

Genotyping and outcomes of presumptive second line ART failure cases switched to third line or maintained on second line ART in Mumbai, India

Gill N, Van Den Berg R, Wut Yee Kyaw K, Laxmeshwar C, Das M,  et al.
2019-11-21 • PLOS One
2019-11-21 • PLOS One
BACKGROUND:
HIV programs are increasingly confronted with failing antiretroviral therapy (ART), including second-line regimens. WHO has provided guidelines on switching to third-lin...

Yield of systematic longitudinal screening of household contacts of pre-extensively drug resistant (PreXDR) and extensively drug resistant (XDR) tuberculosis patients in Mumbai, India

Paryani R, Gupta V, Singh P, Verma M, Sheikh S,  et al.
2020-05-26 • Tropical Medicine and Infectious Disease
2020-05-26 • Tropical Medicine and Infectious Disease
While risk of tuberculosis (TB) is high among household contacts (HHCs) of pre-extensively drug resistant (pre-XDR) TB and XDR-TB, data on yield of systematic longitudinal screening are ...

Linezolid-Associated Optic Neuropathy in Drug-Resistant Tuberculosis Patients in Mumbai, India

Mehta S, Das M, Laxmeshwar C, Jonckheere S, Thi SS,  et al.
2016-09-09 • PLOS One
2016-09-09 • PLOS One
Patients on linezolid-containing drug-resistant TB (DR-TB) regimen often develop adverse-events, particularly peripheral and optic neuropathy. Programmatic data and experiences of linezo...

Beyond 'cure' and 'treatment success': quality of life of patients with multidrug-resistant tuberculosis

Laxmeshwar C, Stewart AG, Dalal A, Kumar AMV, Kalaiselvi S,  et al.
2019-01-01 • International Journal of Tuberculosis and Lung Disease
2019-01-01 • International Journal of Tuberculosis and Lung Disease
SETTING
Two drug-resistant tuberculosis (DR-TB) sites (MSF Clinic, Jupiter Hospital) in Mumbai, India.

OBJECTIVE
To assess health-related quality of life (HRQoL) and ass...

One step forward: successful end-of-treatment outcomes of patients with drug-resistant tuberculosis who received concomitant bedaquiline and delamanid in Mumbai, India

Das M, Dalal A, Laxmeshwar C, Ravi S, Mamnoon F,  et al.
2021-11-02 • Clinical Infectious Diseases
2021-11-02 • Clinical Infectious Diseases
BACKGROUND
The Médecins Sans Frontières clinic in Mumbai, India, has been providing concomitant bedaquiline (BDQ) and delamanid (DLM) in treatment regimen for patients with drug-resi...

One step forward: Successful end-of-treatment outcomes of drug-resistant TB patients who received concomitant bedaquiline and delamanid in Mumbai, India

Das M, Dalal A, Laxmeshwar C, Ravi S, Mamnoon F,  et al.
2020-10-20 • Clinical Infectious Diseases
2020-10-20 • Clinical Infectious Diseases
Background
Médecins Sans Frontières clinic in Mumbai, India has been providing concomitant Bedaquiline (BDQ) and Delamanid (DLM) in treatment regimen for patients with drug-resistan...