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v2.1.5153.produseast1
Showing 1 - 14 of 14 Items
Showing 1 - 14 of 14 Items
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Journal Article
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Research

Low-dose yellow fever vaccine in adults in Africa

Kimathi D, Juan-Giner A, Bob NS, Orindi B, Namulwana ML,  et al.
2025-02-20 • New England Journal of Medicine
2025-02-20 • New England Journal of Medicine

BACKGROUND

Yellow fever vaccine is highly effective with a single dose, but vaccine supply is limited. The minimum dose requirements for seroconversion remain u...

Journal Article
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Commentary

Accumulating evidence on the long-term immunogenicity of fractional dosing for yellow fever vaccines

Juan-Giner A, Warimwe GM
2024-06-01 • Lancet Infectious Diseases
2024-06-01 • Lancet Infectious Diseases
Journal Article
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Commentary

The life-long protective immunity of yellow fever vaccination: time to review?

Juan-Giner A, Hombach J
2024-03-01 • Lancet Global Health
2024-03-01 • Lancet Global Health
Journal Article
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Research

Immunogenicity and safety of fractional doses of 17D-213 yellow fever vaccine in children (YEFE): a randomised, double-blind, non-inferiority substudy of a phase 4 trial

Juan-Giner A, Namulwana ML, Kimathi D, Grantz KH, Fall G,  et al.
2023-04-28 • Lancet Infectious Diseases
2023-04-28 • Lancet Infectious Diseases
BACKGROUND
Current supply shortages constrain yellow fever vaccination activities, particularly outbreak response. Although fractional doses of all WHO-prequalified yellow fever vacc...
Journal Article
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Research

Evaluation of the stability of measles vaccine out of the cold chain under extended controlled temperature conditions

Juan-Giner A, Alsalhani A, Panunzi I, Lambert V, Van Herp M,  et al.
2020-02-08 • Vaccine
2020-02-08 • Vaccine
Measles outbreaks occur periodically in remote and difficult to reach areas in countries such as the Democratic Republic of Congo. The possibility to keep measles vaccines at temperature...
Journal Article
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Research

Characteristics of human encounters and social mixing patterns relevant to infectious diseases spread by close contact: a survey in Southwest Uganda

le Polain de Waroux O, Cohuet S, Ndazima D, Kucharski AJ, Juan-Giner A,  et al.
2018-04-11 • BMC Infectious Diseases
2018-04-11 • BMC Infectious Diseases
BACKGROUND
Quantification of human interactions relevant to infectious disease transmission through social contact is central to predict disease dynamics, yet data from low-resource ...
Journal Article
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Research

Humoral and cellular immune response induced by rVSVΔG-ZEBOV-GP vaccine among frontline workers during the 2013-2016 West Africa Ebola outbreak in Guinea

Boum Y II, Juan-Giner A, Hitchings MD, Soumah A, Strecker T,  et al.
2020-06-01 • Vaccine
2020-06-01 • Vaccine
Background
As part of a Phase III trial with the Ebola vaccine rVSVΔG-ZEBOV-GP in Guinea, we invited frontline workers (FLWs) to participate in a sub-study to provide additional inf...
Journal Article
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Research

A cluster randomized non-inferiority field trial on the immunogenicity and safety of tetanus toxoid vaccine kept in controlled temperature chain compared to cold chain

Juan-Giner A, Domicent C, Langendorf C, Roper M, Baoundoh P,  et al.
2014-09-23 • Vaccine
2014-09-23 • Vaccine
In resource-poor settings, cold chain requirements present barriers for vaccine delivery. We evaluated the immunogenicity and safety of tetanus toxoid (TT) vaccine in "Controlled Tempera...
Journal Article
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Research

Immunogenicity and safety of fractional doses of yellow fever vaccines: a randomised, double-blind, non-inferiority trial

Juan-Giner A, Kimathi D, Grantz KH, Hamaluba M, Kazooba P,  et al.
2021-01-09 • Lancet
2021-01-09 • Lancet
BACKGROUND
Stocks of yellow fever vaccine are insufficient to cover exceptional demands for outbreak response. Fractional dosing has shown efficacy, but evidence is limited to the 17...
Journal Article
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Research

Factors influencing participation in an Ebola vaccine trial among frontline workers in Guinea

Grantz KH, Claudot P, Kambala M, Kouyate M, Soumah A,  et al.
2019-11-15 • Vaccine
2019-11-15 • Vaccine
BACKGROUND
Alongside the clinical aspects of the immunogenicity and safety trial of an Ebola vaccine deployed among front-line workers, a qualitative study was conducted to describe ...
Journal Article
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Research

Factors influencing participation in an Ebola vaccine trial among front-line workers in Guinea

Grantz KH, Claudot P, Kambala M, Kouyate M, Soumah A,  et al.
2019-11-15 • Vaccine
2019-11-15 • Vaccine
BACKGROUND
Alongside the clinical aspects of the immunogenicity and safety trial of an Ebola vaccine deployed among front-line workers, a qualitative study was conducted to describe ...
Journal Article
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Research

Measles seroprevalence in Chiradzulu district, Malawi: implications for evaluating vaccine coverage

Polonsky JA, Juan-Giner A, Hurtado N, Masiku C, Kagoli M,  et al.
2015-07-26 • Vaccine
2015-07-26 • Vaccine
INTRODUCTION
Self-reported measles vaccination coverage is frequently used to inform vaccination strategies in resource-poor settings. However, little is known to what extent this is...
Journal Article
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Commentary

Vaccination in humanitarian crises: satisficing should no longer suffice

Grais RF, Juan-Giner A
2014-08-04 • International Health
2014-08-04 • International Health
There are more possible vaccination interventions to mitigate the adverse health consequences of populations in crises than ever before, but recent reviews suggest delivering these vacci...
Journal Article
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Research

Safety of the rVSV ZEBOV vaccine against Ebola Zaire among frontline workers in Guinea

Juan-Giner A, Tchaton M, Jemmy J-P, Soumah A, Boum Y II,  et al.
2018-09-25 • Vaccine
2018-09-25 • Vaccine
As part of the ring vaccination trial in Guinea, Front Line Workers were invited to participate in a sub-study to provide additional information on the immunogenicity and safety of rVSVΔ...