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18 result(s)
Journal Article > CommentaryFull Text

Operational research training: the course and beyond

Public Health Action. 21 September 2012; Volume 2 (Issue 3); DOI:10.5588/pha.12.0022
Bissell K, Harries AD, Reid A, Edginton ME, Hinderaker SG,  et al.
Public Health Action. 21 September 2012; Volume 2 (Issue 3); DOI:10.5588/pha.12.0022
Journal Article > LetterFull Text

Applying the ICMJE authorship criteria to operational research in low-income countries: the need to engage programme managers and policy makers [letter]

Trop Med Int Health. 30 May 2013; Volume 18 (Issue 8); DOI:10.1111/tmi.12133
Zachariah R, Reid AJ, Van der Bergh R, Dahmane A, Kosgei RJ,  et al.
Trop Med Int Health. 30 May 2013; Volume 18 (Issue 8); DOI:10.1111/tmi.12133
Journal Article > ResearchFull Text

High quit rate among smokers with tuberculosis in a modified smoking cessation programme in Dhaka, Bangladesh

Public Health Action. 21 September 2013; Volume 3 (Issue 3); 243-6.; DOI:10.5588/pha.13.0051
Siddiquea BN, Islam MS, Bam TS, Satyanarayana S, Enarson D,  et al.
Public Health Action. 21 September 2013; Volume 3 (Issue 3); 243-6.; DOI:10.5588/pha.13.0051
SETTING
BRAC, a non-governmental organisation, implemented a modified smoking cessation programme for tuberculosis (TB) patients based on International Union Against Tuberculosis and Lung Disease (The Union) guidelines in 17 peri-urban centres of Dhaka, Bangladesh.

OBJECTIVE
To determine whether a modified version of The Union's smoking cessation intervention was effective in promoting cessation among TB patients and determinants associated with quitting smoking.

DESIGN
Cohort study of routinely collected data.

RESULTS
A total of 3134 TB patients were registered from May 2011 to April 2012. Of these, 615 (20%) were current smokers, with a mean age of 38 years (±13.8). On treatment completion, 562 patients were analysed, with 53 (9%) lost to follow-up or dead, while 82% of smokers had quit. Patients with extra-pulmonary TB were less likely to quit than those with pulmonary TB. Patients with high-intensity dependence were less likely to quit than those with low-intensity dependence.

CONCLUSION
This study suggests that a simplified smoking cessation intervention can be effective in promoting smoking cessation among TB patients in Bangladesh. This is encouraging for other low-resource settings; the Bangladesh National Tuberculosis Control Programme should consider nationwide scaling up and integration of this smoking cessation plan.
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Journal Article > ResearchFull Text

The looming epidemic of diabetes-associated tuberculosis: learning lessons from HIV-associated tuberculosis

Int J Tuberc Lung Dis. 6 September 2011; Volume 15 (Issue 11); DOI:10.5588/ijtld.11.0503
Harries AD, Lin YD, Satyanarayana S, Lonnroth K, Li L,  et al.
Int J Tuberc Lung Dis. 6 September 2011; Volume 15 (Issue 11); DOI:10.5588/ijtld.11.0503
The prevalence of diabetes mellitus is increasing at a dramatic rate, and countries in Asia, particularly India and China, will bear the brunt of this epidemic. Persons with diabetes have a significantly increased risk of active tuberculosis (TB), which is two to three times higher than in persons without diabetes. In this article, we argue that the epidemiological interactions and the effects on clinical presentation and treatment resulting from the interaction between diabetes and TB are similar to those observed for human immunodeficiency virus (HIV) and TB. The lessons learned from approaches to reduce the dual burden of HIV and TB, and especially the modes of screening for the two diseases, can be adapted and applied to the screening, diagnosis, treatment and prevention of diabetes and TB. The new World Health Organization (WHO) and The Union Collaborative Framework for care and control of TB and diabetes has many similarities to the WHO Policy on Collaborative Activities to reduce the dual burden of TB and HIV, and aims to guide policy makers and implementers on how to move forward and combat this looming dual epidemic. The response to the growing HIV-associated TB epidemic in the 1980s and 1990s was slow and uncoordinated, despite clearly articulated warnings about the scale of the forthcoming problem. We must not make the same mistake with diabetes and TB. The Framework provides a template for action, and it is now up to donors, policy makers and implementers to apply the recommendations in the field and to 'learn by doing'.More
Journal Article > CommentaryFull Text

Language in tuberculosis services: can we change to patient-centred terminology and stop the paradigm of blaming the patients?

Int J Tuberc Lung Dis. 16 June 2012 (Issue 6)
Zachariah R, Harries AD, Srinath S, Ram S, Viney K,  et al.
Int J Tuberc Lung Dis. 16 June 2012 (Issue 6)
The words 'defaulter', 'suspect' and 'control' have been part of the language of tuberculosis (TB) services for many decades, and they continue to be used in international guidelines and in published literature. From a patient perspective, it is our opinion that these terms are at best inappropriate, coercive and disempowering, and at worst they could be perceived as judgmental and criminalising, tending to place the blame of the disease or responsibility for adverse treatment outcomes on one side-that of the patients. In this article, which brings together a wide range of authors and institutions from Africa, Asia, Latin America, Europe and the Pacific, we discuss the use of the words 'defaulter', 'suspect' and 'control' and argue why it is detrimental to continue using them in the context of TB. We propose that 'defaulter' be replaced with 'person lost to follow-up'; that 'TB suspect' be replaced by 'person with presumptive TB' or 'person to be evaluated for TB'; and that the term 'control' be replaced with 'prevention and care' or simply deleted. These terms are non-judgmental and patient-centred. We appeal to the global Stop TB Partnership to lead discussions on this issue and to make concrete steps towards changing the current paradigm.More
Journal Article > Short ReportFull Text

Why ethics is indispensable for good-quality operational research [Short communication]

Public Health Action. 21 March 2012; Volume 2 (Issue 1); DOI:10.5588/pha.12.0001
Edginton ME, Enarson D, Zachariah R, Reid AJ, Satyanarayana S,  et al.
Public Health Action. 21 March 2012; Volume 2 (Issue 1); DOI:10.5588/pha.12.0001
Journal Article > ResearchFull Text

Impact of Introducing the Line Probe Assay on Time to Treatment Initiation of MDR-TB in Delhi, India

PLOS One. 24 July 2014; Volume 9 (Issue 7); DOI:10.1371/journal.pone.0102989
Singla N, Sathyanarayana S, Sachdeva KS, Van der Bergh R, Reid AJ,  et al.
PLOS One. 24 July 2014; Volume 9 (Issue 7); DOI:10.1371/journal.pone.0102989
National Institute of Tuberculosis and Respiratory Diseases (erstwhile Lala Ram Sarup Institute) in Delhi, India.
Journal Article > ResearchFull Text

Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients

PLOS Med. 28 August 2012; Volume 9 (Issue 8); DOI:10.1371/journal.pmed.1001300
Ahuja SD, Ashkin D, Avendano M, Banerjee R, Bayona J,  et al.
PLOS Med. 28 August 2012; Volume 9 (Issue 8); DOI:10.1371/journal.pmed.1001300
Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic, expensive, and has generally poor outcomes. We undertook an individual patient data meta-analysis to assess the impact on outcomes of the type, number, and duration of drugs used to treat MDR-TB.More
Journal Article > ResearchFull Text

Profile and treatment outcomes of elderly patients with tuberculosis in Delhi, India: implications for their management

Trans R Soc Trop Med Hyg. 4 November 2013; Volume 107 (Issue 12); DOI:10.1093/trstmh/trt094
Patra S, Lukhmana S, Tayler-Smith K, Kannan AT, Satyanarayana S,  et al.
Trans R Soc Trop Med Hyg. 4 November 2013; Volume 107 (Issue 12); DOI:10.1093/trstmh/trt094
Given India's high rate of TB, rising burden of non-communicable diseases (NCDs) and growing elderly population, elderly TB patients may be at higher risk of adverse outcomes including death, loss-to-follow-up (LTFU) and treatment failure. This may call for modifications in their management. This study thus aimed to compare the profile and treatment outcomes between elderly (≥60 years) and non-elderly (15-59 years) TB patients.More
Journal Article > ResearchFull Text

Can follow-up examination of tuberculosis patients be simplified? A study in Chhattisgarh, India

PLOS One. 5 December 2012; Volume 7 (Issue 12); DOI:10.1371/journal.pone.0051038
Kumar AMV, Satyanarayana S, Dewan P, Nair SA, Khaparde K,  et al.
PLOS One. 5 December 2012; Volume 7 (Issue 12); DOI:10.1371/journal.pone.0051038
Each follow-up during the course of tuberculosis treatment currently requires two sputum examinations. However, the incremental yield of the second sputum sample during follow-up of different types of tuberculosis patients has never been determined precisely.More