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Showing 1 - 11 of 11 Items
Showing 1 - 11 of 11 Items
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Conference Material
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Abstract

Facilitating safe discharge through predicting disease progression in moderate COVID-19: development and validation of a prediction model in resource-limited settings

Chandna A, PRIORITISE Study Group, Mahajan R, Gautam P, Mwandigha L,  et al.
2022-05-09 • MSF Scientific Days International 2022
2022-05-09 • MSF Scientific Days International 2022
INTRODUCTION
In locations where few people have received Covid-19 vaccines, health systems remain vulnerable to spikes in SARS-CoV-2 infections. Triage tools, which could include bio...
Journal Article
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Research

Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial

Dondorp AM, Fanello CI, Hendriksen IC, Gomes E, Seni A,  et al.
2010-11-08 • Lancet
2010-11-08 • Lancet
Severe malaria is a major cause of childhood death and often the main reason for paediatric hospital admission in sub-Saharan Africa. Quinine is still the established treatment of choice...
Journal Article
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Short Report

Community participation during two mass anti-malarial administrations in Cambodia: lessons from a joint workshop

Peto TJ, Debackere M, Etienne W, Vernaeve L, Tripura R,  et al.
2018-01-27 • Malaria Journal
2018-01-27 • Malaria Journal
Two mass drug administrations (MDA) against falciparum malaria were conducted in 2015-16, one as operational research in northern Cambodia, and the other as a clinical trial in western C...
Journal Article
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Research

An optimised age-based dosing regimen for single low-dose primaquine for blocking malaria transmission in Cambodia

Leang R, Khu NH, Mukaka M, Debackere M, Tripura R,  et al.
2016-10-27 • BMC Medicine
2016-10-27 • BMC Medicine
BACKGROUND
In 2012, the World Health Organization recommended the addition of single low-dose primaquine (SLDPQ, 0.25 mg base/kg body weight) to artemisinin combination therapies to ...
Journal Article
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Review

Novel Approaches to Control Malaria in Forested Areas of Southeast Asia

von Seidlein L, Peto TJ, Tripura R, Pell C, Yeung S,  et al.
2019-05-07
2019-05-07
The emergence and spread of drug resistance in the Greater Mekong Subregion (GMS) have added urgency to accelerate malaria elimination while reducing the treatment options. The remaining...
Journal Article
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Research

Development of weight and age-based dosing of daily primaquine for radical cure of vivax malaria

Taylor WRJ, Hoglund RM, Peerawaranun P, Nguyen TN, Hien TT,  et al.
2021-09-09 • Malaria Journal
2021-09-09 • Malaria Journal
BACKGROUND
In many endemic areas, Plasmodium vivax malaria is predominantly a disease of young adults and children. International recommendations for radical cure recommend fixed tar...
Protocol
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Research Protocol

Prediction of disease severity in young children presenting with acute febrile illness in resource-limited settings: a protocol for a prospective observational study

Chandna A, Aderie EM, Ahmad R, Arguni E, Ashley EA,  et al.
2021-01-25 • BMJ Open
2021-01-25 • BMJ Open
INTRODUCTION
In rural and difficult-to-access settings, early and accurate recognition of febrile children at risk of progressing to serious illness could contribute to improved pati...
Journal Article
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Research

Facilitating safe discharge through predicting disease progression in moderate COVID-19: a prospective cohort study to develop and validate a clinical prediction model in resource-limited settings

Chandna A, Mahajan R, Gautam P, Mwandigha L, Gunasekaran K,  et al.
2022-03-21 • Clinical Infectious Diseases
2022-03-21 • Clinical Infectious Diseases
BACKGROUND
In locations where few people have received COVID-19 vaccines, health systems remain vulnerable to surges in SARS-CoV-2 infections. Tools to identify patients suitable for...
Journal Article
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Research

Assessing the asymptomatic reservoir and dihydroartemisinin-piperaquine effectiveness in a low transmission setting threatened by artemisinin resistant Plasmodium falciparum

Falq G, Van der Bergh R, de Smet M, Etienne W, Nguon C,  et al.
2016-09-01 • Malaria Journal
2016-09-01 • Malaria Journal
BACKGROUND
In Cambodia, elimination of artemisinin resistance through direct elimination of the Plasmodium falciparum parasite may be the only strategy. Prevalence and incidence at d...
Journal Article
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Research

Optimal health and disease management using spatial uncertainty: a geographic characterization of emergent artemisinin-resistant plasmodium falciparum distributions in Southeast Asia

Grist EP, Fleqq JA, Humphreys G, Mas IS, Anderson TJC,  et al.
2016-10-24 • International Journal of Health Geographics
2016-10-24 • International Journal of Health Geographics
BACKGROUND
Artemisinin-resistant Plasmodium falciparum malaria parasites are now present across much of mainland Southeast Asia, where ongoing surveys are measuring and mapping their...
Journal Article
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Research

The risk of Plasmodium vivax parasitaemia after P. falciparum malaria: An individual patient data meta-analysis from the WorldWide Antimalarial Resistance Network

Hossain MS, Commons RJ, Douglas NM, Thriemer KL, Alemayehu BH,  et al.
2020-11-19 • PLOS Medicine
2020-11-19 • PLOS Medicine
Background: There is a high risk of Plasmodium vivax parasitaemia following treatment of falciparum malaria. Our study aimed to quantify this risk and the associated determinants using a...