Showing 1 - 14 of 14 Items
Showing 1 - 14 of 14 Items
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Journal Article
|Research
2024-09-12 • PLOS Medicine
2024-09-12 • PLOS Medicine
BACKGROUND
Hydroxychloroquine (HCQ) has proved ineffective in treating patients hospitalised with Coronavirus Disease 2019 (COVID-19), but uncertainty remains over its safety an...
Journal Article
|Research
2013-11-13 • CPT: Pharmacometrics and Systems Pharmacology
2013-11-13 • CPT: Pharmacometrics and Systems Pharmacology
Pregnancy alters the pharmacokinetic properties of many antimalarial compounds. The objective of this study was to evaluate the pharmacokinetic properties of lumefantrine in pregnant and...
Conference Material
|Abstract
2022-05-09 • MSF Scientific Days International 2022
2022-05-09 • MSF Scientific Days International 2022
INTRODUCTION
In locations where few people have received Covid-19 vaccines, health systems remain vulnerable to spikes in SARS-CoV-2 infections. Triage tools, which could include bio...
In locations where few people have received Covid-19 vaccines, health systems remain vulnerable to spikes in SARS-CoV-2 infections. Triage tools, which could include bio...
Journal Article
|Research
2010-11-08 • Lancet
2010-11-08 • Lancet
Severe malaria is a major cause of childhood death and often the main reason for paediatric hospital admission in sub-Saharan Africa. Quinine is still the established treatment of choice...
Journal Article
|Research
2007-04-01 • Journal of Infectious Diseases
2007-04-01 • Journal of Infectious Diseases
BACKGROUND: Relapses originating from hypnozoites are characteristic of Plasmodium vivax infections. Thus, reappearance of parasitemia after treatment can result from relapse, recrudesce...
Protocol
|Research Protocol
2021-01-25 • BMJ Open
2021-01-25 • BMJ Open
INTRODUCTION
In rural and difficult-to-access settings, early and accurate recognition of febrile children at risk of progressing to serious illness could contribute to improved pati...
In rural and difficult-to-access settings, early and accurate recognition of febrile children at risk of progressing to serious illness could contribute to improved pati...
Journal Article
|Research
2022-03-21 • Clinical Infectious Diseases
2022-03-21 • Clinical Infectious Diseases
BACKGROUND
In locations where few people have received COVID-19 vaccines, health systems remain vulnerable to surges in SARS-CoV-2 infections. Tools to identify patients suitable for...
In locations where few people have received COVID-19 vaccines, health systems remain vulnerable to surges in SARS-CoV-2 infections. Tools to identify patients suitable for...
Journal Article
|Research
2004-11-01 • Antimicrobial Agents and Chemotherapy
2004-11-01 • Antimicrobial Agents and Chemotherapy
To determine the optimum duration of follow-up for the assessment of drug efficacy against Plasmodium falciparum malaria, 96 trial arms from randomized controlled trials (RCTs) with foll...
Journal Article
|Research
2008-03-01 • Antimicrobial Agents and Chemotherapy
2008-03-01 • Antimicrobial Agents and Chemotherapy
The population pharmacokinetics of piperaquine in adults and children with uncomplicated Plasmodium falciparum malaria treated with two different dosage regimens of dihydroartemisinin-pi...
Conference Material
|Slide Presentation
2022-05-10 • MSF Scientific Days International 2022
2022-05-10 • MSF Scientific Days International 2022
Journal Article
|Research
2016-10-24 • International Journal of Health Geographics
2016-10-24 • International Journal of Health Geographics
BACKGROUND
Artemisinin-resistant Plasmodium falciparum malaria parasites are now present across much of mainland Southeast Asia, where ongoing surveys are measuring and mapping their...
Artemisinin-resistant Plasmodium falciparum malaria parasites are now present across much of mainland Southeast Asia, where ongoing surveys are measuring and mapping their...
Journal Article
|Research
2008-08-01 • Malaria Journal
2008-08-01 • Malaria Journal
BACKGROUND: Malaria is a very important cause of anaemia in tropical countries. Anaemia is assessed either by measurement of the haematocrit or the haemoglobin concentration. For compari...
Journal Article
|Research
2010-02-15 • Journal of Infectious Diseases
2010-02-15 • Journal of Infectious Diseases
Parasite clearance data from 18,699 patients with falciparum malaria treated with an artemisinin derivative in areas of low (n=14,539), moderate (n=2077), and high (n=2083) levels of mal...
Journal Article
|Research
2018-01-18 • BMC Medicine
2018-01-18 • BMC Medicine
In 2012, the World Health Organization recommended blocking the transmission of Plasmodium falciparum with single low-dose primaquine (SLDPQ, target dose 0.25 mg base/kg body weight), wi...