Search Results | MSF Science Portal

Journal Article

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Research

ter Horst R, Tefera T, Assefa G, Ebrahim AZ, Davidson RN, et al.

2009-06-01 • American Journal of Tropical Medicine and Hygiene

Accuracy of an rK39 rapid diagnostic test (DiaMed-IT-Leish ) for visceral leishmaniasis (VL) was compared with splenic aspiration and the direct agglutination test (DAT) in a population ...

Journal Article

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Research

Mueller M, Ritmeijer KKD, Balasegaram M, Koummuki Y, Santana MR, et al.

2007-01-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene

In Sudan, two treatments are currently registered for visceral leishmaniasis: sodium stibogluconate (SSG) as first line and liposomal amphotericin B (AmBisome) as second line. We present...

Journal Article

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Research

Belay AD, Asafa Y, Mesure J, Davidson RN

2006-04-01 • Annals of Tropical Medicine and Parasitology

The first two patients to be treated with miltefosine for post-kala-azar dermal leishmaniasis (PKDL) are reported. One was a 26-year-old Ethiopian man who had been treated with sodium st...

Journal Article

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Research

Veeken H, Ritmeijer KKD, Seaman J, Davidson RN

2000-05-01 • Tropical Medicine and International Health

OBJECTIVE
To compare the outcome of treatment of Sudanese kala-azar patients treated under field conditions with either branded sodium stibogluconate (SSG) (Pentostam GlaxoWellcome) ...

Protocol

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Research Protocol

Diro EGJ, Griensven JV, Woldegebreal T, Belew Z, Taye M, et al.

2018-07-01

2.1 OBJECTIVES
2.1.1 General objective:

To document the effectiveness, safety and feasibility of monthly PM secondary prophylaxis (PSP) in VL/HIV co-infected patients t...

Journal Article

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Research

Veeken H, Ritmeijer KKD, Seaman J, Davidson RN

2003-02-01 • Tropical Medicine and International Health

We compared an rK39 dipstick rapid test (Amrad ICT, Australia) with a direct agglutination test (DAT) and splenic aspirate for the diagnosis of kala-azar in 77 patients. The study was ca...

Journal Article

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Research

Ritmeijer KKD, Melaku Y, Mueller M, Kipngetich S, O'keeffe C, et al.

2006-01-01 • American Journal of Tropical Medicine and Hygiene

A new rK39 rapid diagnostic dipstick test (DiaMed-IT-Leish) was compared with aspiration and a direct agglutination test (DAT) for diagnosis of visceral leishmaniasis (VL) in 201 parasit...

Journal Article

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Research

Balasegaram M, Dejene S, Tinnemann P, Perkins S, Davidson RN

2006-04-01 • Transactions of the Royal Society of Tropical Medicine and Hygiene

Humanitarian medical programmes in the tropics have the opportunity to provide beacons of good practice. The use of modern drugs and diagnostics, a lack of bureaucracy, adequate budgets,...

Journal Article

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Research

Ritmeijer KKD, ter Horst R, Chane S, Aderie EM, Piening T, et al.

2011-10-19 • Clinical Infectious Diseases

Due to unacceptably high mortality with pentavalent antimonials, Médecins Sans Frontières in 2006 began using liposomal amphotericin B (AmBisome) for visceral leishmaniasis (VL) patients...

Journal Article

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Research

Ritmeijer KKD, Veeken H, Melaku Y, Leal G, Amsalu R, et al.

2008-01-31 • Transactions of the Royal Society of Tropical Medicine and Hygiene

We evaluated generic sodium stibogluconate (SSG) (International Dispensary Association, Amsterdam) versus Pentostam (sodium stibogluconate, GlaxoWellcome, London) under field conditions ...

Journal Article

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Research

Ritmeijer KKD, Davidson RN

2008-02-14 • Transactions of the Royal Society of Tropical Medicine and Hygiene

Since 1989, Médecins Sans Frontières (MSF) has provided medical humanitarian assistance during outbreaks of visceral leishmaniasis (VL; kala-azar) in Sudan. First, in western Upper Nile ...

Journal Article

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Research

Babiker ZOE, Davidson RN, Mazinda CS, Kipngetich S, Ritmeijer KKD

2007-04-01 • American Journal of Tropical Medicine and Hygiene

We evaluated lymph node aspiration (LNA) as a simple diagnostic procedure for visceral leishmaniasis (VL). Lymph node aspiration was compared with the direct agglutination test (DAT) usi...

Journal Article

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Research

Ritmeijer KKD, Dejenie A, Assefa Y, Hundie TB, Mesure J, et al.

2006-08-01 • Clinical Infectious Diseases

BACKGROUND: Antimonials are the mainstay of visceral leishmaniasis (VL) treatment in Africa. The increasing incidence of human immunodeficiency virus (HIV) coinfection requires alternati...

Journal Article

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Commentary

den Boer ML, Alvar J, Davidson RN, Ritmeijer KKD, Balasegaram M

2009-08-27 • Expert Opinion on Emerging Drugs

BACKGROUND: Visceral leishmaniasis (VL) is one of the most neglected parasitic diseases causing large scale mortality and morbidity among the poorest of the poor in the Indian subcontine...

Journal Article

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Research

Seaman J, Boer C, Wilkinson RJ, de Jong J, de Wilde E, et al.

1995-07-01 • Clinical Infectious Diseases

An open trial of liposomal amphotericin B (AmBisome [L-AmB]; Vestar, San Dimas, CA) for treatment of complicated visceral leishmaniasis was performed in Sudan. Forty-nine patients were t...

Journal Article

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Research

Mueller M, Balasegaram M, Koummuki Y, Ritmeijer KKD, Santana MR, et al.

2006-10-01 • Journal of Antimicrobial Chemotherapy

OBJECTIVES: Little is known about the treatment of visceral leishmaniasis (VL) in pregnancy, especially in resource-poor settings. We present a series of pregnant women with VL treated w...

Journal Article

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Research

Gorski S, Collin SM, Ritmeijer KKD, Keus K, Gatluak F, et al.

2010-06-08 • PLOS Neglected Tropical Diseases

BACKGROUND: Risk factors associated with L. donovani visceral leishmaniasis (VL; kala azar) relapse are poorly characterized. METHODS: We investigated patient characteristics and drug re...

Journal Article

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Research

Marlet MVL, Sang DK, Ritmeijer KKD, Muga RO, Onsongo J, et al.

2008-01-31 • Transactions of the Royal Society of Tropical Medicine and Hygiene

Visceral leishmaniasis (VL) was known to be endemic in Somalia along the basins of the (Middle) Shebelle and (Lower) Juba rivers, and in Kenya in parts of the Rift Valley, on the border ...

Journal Article

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Research

Seaman J, Pryce D, Sondorp H, Moody A, Bryceson A, et al.

1993-09-01 • Journal of Infectious Diseases

In a comparative trial of treatment in southern Sudan, visceral leishmaniasis was diagnosed by the following symptoms: fever for > 1 month, splenomegaly, and antileishmanial direct agglu...

Journal Article

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Research

Melaku Y, Collin SM, Keus K, Gatluak F, Ritmeijer KKD, et al.

2007-07-01 • American Journal of Tropical Medicine and Hygiene

Médecins sans Frontières-Holland has treated > 67,000 patients with kala-azar (KA) in southern Sudan since 1989. In 2002, we replaced the standard regimen of 30 days of daily sodium stib...

Science Portal

Field evaluation of rK39 test and direct agglutination test for diagnosis of visceral leishmaniasis in a population with high prevalence of human immunodeficiency virus in Ethiopia

Unresponsiveness to AmBisome in some Sudanese patients with kala-azar

Successful Miltefosine Treatment of Post-Kala-Azar Dermal Leishmaniasis Occurring During Antiretroviral Therapy

A randomized comparison of branded sodium stibogluconate and generic sodium stibogluconate for the treatment of visceral leishmaniasis under field conditions in Sudan

Secondary prophylaxis of visceral leishmaniasis relapses in HIV co-infected patients using pentamidine as a prophylactic agent: a prospective cohort study

Comparison of an rK39 dipstick rapid test with direct agglutination test and splenic aspiration for the diagnosis of kala-azar in Sudan

Evaluation of a new recombinant K39 rapid diagnostic test for Sudanese visceral leishmaniasis

Examples of tropical disease control in the humanitarian medical programmes of MSF and Merlin

Limited effectiveness of high-dose liposomal amphotericin B (AmBisome) for treatment of visceral leishmaniasis in an Ethiopian population with high HIV prevalence

Ethiopian visceral leishmaniasis: generic and proprietary sodium stibogluconate are equivalent; HIV co-infected patients have a poor outcome

Royal Society of Tropical Medicine and Hygiene joint meeting with Médecins Sans Frontières at Manson House, London, 20 March 2003: field research in humanitarian medical programmes. Médecins Sans Frontières interventions against kala-azar in the Sudan, 1989-2003

Utility of lymph node aspiration in the diagnosis of visceral leishmaniasis in Sudan

A comparison of miltefosine and sodium stibogluconate for treatment of visceral leishmaniasis in an Ethiopian population with high prevalence of HIV infection

Developments in the treatment of visceral leishmaniasis

Liposomal Amphotericin B (AmBisome) in the Treatment of Complicated Kala-Azar Under Field Conditions

A comparison of liposomal Amphotericin B with sodium stibogluconate for the treatment of visceral leishmaniasis in pregnancy in Sudan

Visceral leishmaniasis relapse in Southern Sudan (1999-2007): a retrospective study of risk factors and trends

Emergence or re-emergence of visceral leishmaniasis in areas of Somalia, north-eastern Kenya, and south-eastern Ethiopia in 2000-01

Epidemic Visceral Leishmaniasis in Sudan: A Randomized Trial of Aminosidine Plus Sodium Stibogluconate Versus Sodium Stibogluconate Alone

Treatment of kala-azar in Southern Sudan using a 17-day regimen of sodium stibogluconate combined with paromomycin: a retrospective comparison with 30-day sodium stibogluconate monotherapy