Search Results | MSF Science Portal

Journal Article

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Research

Garcia-Prats AJ, Garcia-Cremades M, Cox V, Kredo T, Dunbar R, et al.

2025-02-01 • Lancet Child and Adolescent Health

BACKGROUND

There are few data on the treatment of children and adolescents with multidrug-resistant (MDR) or rifampicin-resistant (RR) tuberculosis, especially ...

Journal Article

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Research

Guglielmetti L, Khan U, Velásquez GE, Gouillou M, Abubakirov A, et al.

2025-01-29 • New England Journal of Medicine

BACKGROUND

For decades, poor treatment options and low-quality evidence plagued care for patients with rifampin-resistant tuberculosis. The advent of new drugs ...

Journal Article

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Research

Guglielmetti L, Khan U, Velasquez GE, Gouillou M, Abubakirov A, et al.

2024-01-29 • medRxiv

BACKGROUND

Aft...

Journal Article

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Research

du Cros PAK, Greig J, Cross GB, Cousins C, Berry C, et al.

2023-12-01 • International Journal of Tuberculosis and Lung Disease

BACKGROUND
The value, speed of completion and robustness of the evidence generated by TB treatment trials could be improved by implementing standards for best practice.

METH...

Journal Article

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Letter

Patten GE, Cox V, Stinson K, Boulle AM, Wilkinson LS

2014-04-23 • Clinical Infectious Diseases

Journal Article

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Review

Stinson K, Goemaere E, Coetzee D, van Cutsem G, Hilderbrand K, et al.

2016-05-20 • International Journal of Epidemiology

Journal Article

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Research

Cox V, De Azevedo V, Stinson K, Wilkinson LS, Rangaka MX, et al.

2015-11-01 • International Journal of Tuberculosis and Lung Disease

BACKGROUND
The World Health Organization recommends tuberculin skin tests (TSTs) where feasible to identify individuals most likely to benefit from isoniazid preventive therapy (IPT)...

Journal Article

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Short Report

Nelson AM, Maritz J, Giddy J, Frigati L, Rabie H, et al.

2015-04-28 • Southern African Journal of HIV medicine

Journal Article

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Letter

Hughes J, Isaakidis P, Andries A, Mansoor H, Cox V, et al.

2015-12-01 • European Respiratory Journal

Journal Article

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Research

Sharp J, Wilkinson LS, Cox V, Cragg C, van Custem G, et al.

2019-06-11 • Southern African Journal of HIV medicine

BACKGROUND
Eligibility for differentiated antiretroviral therapy (ART) delivery models has to date been limited to low-risk stable patients.
OBJECTIVES
We examined the outcom...

Journal Article

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Research

Daniels J, Khogali MA, Mohr E, Cox V, Moyo S, et al.

2015-11-10 • PLOS One

SETTING
Khayelitsha, South Africa, with high burdens of rifampicin-resistant tuberculosis (RR-TB) and HIV co-infection.

OBJECTIVE
To describe time to antiretroviral trea...

Journal Article

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Letter

Stinson K, Ford NP, Cox V, Boulle AM

2014-02-05 • Clinical Infectious Diseases

Journal Article

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Research

Fajardo E, Metcalf CJ, Piriou E, Gueguen M, Maman D, et al.

2015-06-25 • Bulletin of the World Health Organization

OBJECTIVE
To estimate the proportion of invalid results generated by a CD4+ T-lymphocyte analyser used by Médecins Sans Frontières (MSF) in field projects and identify factors associ...

Journal Article

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Commentary

Cox HS, Furin J, Mitnick CD, Daniels C, Cox V, et al.

2015-07-01 • Bulletin of the World Health Organization

Approximately half a million people are thought to develop multidrug-resistant tuberculosis annually. Barely 20% of these people currently receive recommended treatment and only about 10...

Journal Article

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Research

Schomaker M, Leroy V, Wolfs T, Technau KG, Renner L, et al.

2016-06-24 • International Journal of Epidemiology

Background: There is limited knowledge about the optimal timing of antiretroviral treatment initiation in older children and adolescents. Methods: A total of 20 576 antiretroviral treatm...

Journal Article

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Research

Nelson AM, Cassidy T, Duran LT, Cox V, Wedderburn C, et al.

2022-01-14 • PLOS One

BACKGROUND
Despite the reduction of HIV mother-to-child transmission, there are concerns regarding transmission rate in the breastfeeding period. We describe the routine uptake of 6 ...

Journal Article

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Pre-Print

Cox V, Perrin C, Athersuch K, Martin M M, Alsalhani A

2020-06-01 • OSF Preprints

Two novel drugs, bedaquiline and delamanid, have recently become available to treat drug resistant tuberculosis (DR-TB) after many decades of little innovation in the field of DR-TB trea...

Journal Article

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Letter

Cox HS, van Cutsem G, Cox V

2014-08-01 • Lancet

Journal Article

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Research

Schomaker M, Davies A, Malateste K, Renner L, Sawry S, et al.

2015-10-16 • Epidemiology

Journal Article

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Commentary

Cox V, McKenna L, Acquah R, Reuter A, Wasserman S, et al.

2020-11-01 • International Journal of Tuberculosis and Lung Disease

Rapid diagnostics, newer drugs, repurposed medications, and shorter regimens have radically altered the landscape for treating rifampicin-resistant TB (RR-TB) and multidrug-resistant TB ...

Science Portal

Characteristics of children and adolescents with multidrug-resistant and rifampicin-resistant tuberculosis and their association with treatment outcomes: a systematic review and individual participant data meta-analysis

Oral regimens for rifampin-resistant, fluoroquinolone-susceptible tuberculosis

Nine-month, all-oral regimens for rifampin-resistant tuberculosis

Standards for clinical trials for treating TB

Advanced HIV disease at antiretroviral therapy (ART) initiation despite implementation of expanded ART eligibility guidelines during 2007-2012 in Khayelitsha, South Africa

Cohort profile: the Khayelitsha antiretroviral programme, Cape Town, South Africa

Diagnostic accuracy of tuberculin skin test self-reading by HIV patients in a low-resource setting

HIV testing and antiretroviral therapy initiation at birth: Views from a primary care setting in Khayelitsha

Linezolid in drug-resistant tuberculosis: haste makes waste

Outcomes of patients enrolled in an antiretroviral adherence club with recent viral suppression after experiencing elevated viral loads

Time to ART initiation among patients treated for rifampin-resistant tuberculosis in Khayelitsha, South Africa: Impact on mortality and treatment success

Patients lost to care are more likely to be viremic than patients still in care

Errors generated by a point-of-care CD4+ T-lymphocyte analyser: a retrospective observational study in nine countries

The need to accelerate access to new drugs for multidrug-resistant tuberculosis

Optimal Timing of Antiretroviral Treatment Initiation in HIV-Positive Children and Adolescents: a Multiregional Analysis from Southern Africa, West Africa and Europe

An analysis of the HIV testing cascade of a group of HIV-exposed infants from birth to 18 months in peri-urban Khayelitsha, South Africa

MSF Access Campaign drug-resistant tuberculosis research and development case study May 2020

Better treatment of XDR tuberculosis needed in South Africa

Growth and mortality outcomes for different antiretroviral therapy initiation criteria in children aged 1-5 years: a causal modelling analysis

Clinical perspectives on treatment of rifampicin-resistant/multidrug-resistant TB