Search Results | MSF Science Portal

Journal Article

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Research

Musumeci S, Kruse A, Chappuis F, Ostergaard Jensen T, Alcoba G

2024-06-21 • PLOS Neglected Tropical Diseases

BACKGROUND
Febrile illnesses that persist despite initial treatment are common clinical challenges in (sub)tropical low-resource settings. Our aim is to review infectious etiologies ...

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Research

Bolon I, Picek L, Durso AM, Alcoba G, Chappuis F, et al.

2022-08-15 • PLOS Neglected Tropical Diseases

BACKGROUND
Snakebite envenoming is a neglected tropical disease that kills an estimated 81,000 to 138,000 people and disables another 400,000 globally every year. The World Health Or...

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Research

Mueller YK, Kolaczinski JH, Koech T, Lokwang P, Riongoita M, et al.

2013-11-11 • American Journal of Tropical Medicine and Hygiene

Between 2000 and 2010, Médecins Sans Frontières diagnosed and treated 4,831 patients with visceral leishmaniasis (VL) in the Pokot region straddling the border between Uganda and Kenya. ...

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Research

Eperon G, Schmid C, Loutan L, Chappuis F

2007-01-01 • Acta Tropica

BACKGROUND: Existing data on human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense among children are limited. Here, we described the demographic, clinical, diagnostic,...

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Research

Schmid C, Richer M, Bilenge CM, Josenando T, Chappuis F, et al.

2005-06-01 • Journal of Infectious Diseases

BACKGROUND: Treatment of late-stage human African trypanosomiasis (HAT) with melarsoprol can be improved by shortening the regimen. A previous trial demonstrated the safety and efficacy ...

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Research

Mueller YK, Nguimfack A, Cavailler P, Couffignal S, Rwakimari JB, et al.

2008-01-01 • Annals of Tropical Medicine and Parasitology

Between September 2003 and April 2004, the supply of antimonial drugs to Amudat Hospital, in north-eastern Uganda, was interrupted and all cases of visceral leishmaniasis presenting at t...

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Research

Balasegaram M, Young H, Chappuis F, Priotto G, Raguenaud ME, et al.

2008-10-21 • Transactions of the Royal Society of Tropical Medicine and Hygiene

This paper describes the effectiveness of first-line regimens for stage 2 human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense infection in nine Médecins Sans Frontièr...

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Short Report

Checchi F, Funk S, Chandramohan D, Haydon DT, Chappuis F

2015-07-04 • BMC Research Notes

BACKGROUND
The duration of the stages of HAT is an important factor in epidemiological studies and intervention planning. Previously, we published estimates of the duration of the ha...

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Research

Chappuis F, Loutan L, Simarro P, Lejon V, Bu¨scher P

2005-01-01 • Clinical Microbiology Reviews

Human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense or T. b. rhodesiense remains highly prevalent in several rural areas of sub-Saharan Africa and is lethal if left u...

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Research

Alcoba G, Ochoa C, Martins SB, Ruiz de Castañeda R, Bolon I, et al.

2021-02-12 • PLOS Neglected Tropical Diseases

BACKGROUND
Worldwide, it is estimated that snakes bite 4.5-5.4 million people annually, 2.7 million of which are envenomed, and 81,000-138,000 die. The World Health Organization repo...

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Research

Longbottom J, Shearer FM, Devine M, Alcoba G, Chappuis F, et al.

2018-07-12 • Lancet

Snakebite envenoming is a frequently overlooked cause of mortality and morbidity. Data for snake ecology and existing snakebite interventions are scarce, limiting accurate burden estimat...

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Research

Chappuis F, Stivanello E, Adams K, Kidane S, Pittet A, et al.

2004-09-01 • American Journal of Tropical Medicine and Hygiene

The diagnosis of human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense relies on an initial serologic screening with the card agglutination test for trypanosomiasis (CA...

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Research

Carnino L, Vetter P, Peyraud N, Aebischer-Perone S, Chappuis F, et al.

2021-06-15 • Journal of Travel Medicine

BACKGROUND AND RATIONALE
Geneva University Hospitals were granted a temporary authorization to administer the recombinant live vesicular stomatitis virus rVSV-ZEBOV (Ervebo®) vaccine...

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Commentary

De Castaneda RR, Durso AM, Ray N, Fernandez JL, Williams DJ, et al.

2019-09-01 • Lancet Digital Health

Journal Article

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Research

Alcoba G, Chabloz M, Eyong J, Wanda F, Ochoa C, et al.

2020-06-25 • PLOS Neglected Tropical Diseases

BACKGROUND
Snakebite envenoming causes 81,000-138,000 annual human deaths and pain, terror, or disability in 4.5-5.4 million victims. Accurate community-based epidemiological data is...

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Commentary

Hasker E, Lutumba P, Chappuis F, Kande V, Potet J, et al.

2012-12-13 • PLOS Neglected Tropical Diseases

Journal Article

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Commentary

Alirol E, Lechevalier P, Zamatto F, Chappuis F, Alcoba G, et al.

2015-09-10 • PLOS Neglected Tropical Diseases

Journal Article

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Commentary

Yun O, Priotto G, Tong J, Flevaud L, Chappuis F

2010-05-25 • PLOS Neglected Tropical Diseases

Journal Article

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Research

Chappuis F, Pittet A, Bovier PA, Adams K, Godineau V, et al.

2002-11-01 • Tropical Medicine and International Health

Most Human African Trypanosomiasis (HAT) control programmes in areas endemic for Trypanosoma brucei gambiense rely on a strategy of active mass screening with the Card Agglutination Test...

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Review

Balasegaram M, Ritmeijer KKD, Lima MA, Burza S, Ortiz Genovese G, et al.

2012-11-20 • Expert Opinion on Emerging Drugs

Science Portal

Neglected etiologies of prolonged febrile illnesses in tropical and subtropical regions: A systematic review

An artificial intelligence model to identify snakes from across the world: Opportunities and challenges for global health and herpetology

Clinical Epidemiology, Diagnosis and Treatment of Visceral Leishmaniasis in the Pokot Endemic Area of Uganda and Kenya

Clinical Presentation and Treatment Outcome of Sleeping Sickness in Sudanese Pre-School Children

Effectiveness of a 10-day melarsoprol schedule for the treatment of late-stage human African trypanosomiasis: confirmation from a multinational study (IMPAMEL II)

Safety and Effectiveness of Amphotericin B Deoxycholate for the Treatment of Visceral Leishmaniasis in Uganda

Effectiveness of melarsoprol and eflornithine as first-line regimens for gambiense sleeping sickness in nine Médecins Sans Frontières programmes

Updated estimate of the duration of the meningo-encephalitic stage in gambiense human African trypanosomiasis

Options for field diagnosis of human african trypanosomiasis

Novel transdisciplinary methodology for cross-sectional analysis of snakebite epidemiology at national scale

Vulnerability to snakebite envenoming: a global mapping of hotspots

Card Agglutination Test for Trypanosomiasis (CATT) end-dilution titer and cerebrospinal fluid cell count as predictors of human African Trypanosomiasis (Trypanosoma brucei gambiense) Among Serologically Suspected Individuals in Southern Sudan

Feasibility and safety of rVSV-ZEBOV vaccination of humanitarian health workers against Ebola virus disease: an observational study

Snakebite and snake identification: empowering neglected communities and health-care providers with AI

Snakebite epidemiology and health-seeking behavior in Akonolinga health district, Cameroon: Cross-sectional study

Human african trypanosomiasis in the democratic republic of the congo: a looming emergency?

Antivenoms for Snakebite Envenoming: What Is in the Research Pipeline?

NECT is next: implementing the new drug combination therapy for Trypanosoma brucei gambiense sleeping sickness

Field evaluation of the CATT/Trypanosoma brucei gambiense on blood-impregnated filter papers for diagnosis of human African trypanosomiasis in southern Sudan

Liposomal amphotericin B as a treatment for human leishmaniasis