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Copyright © Médecins Sans Frontières
v2.1.5209.produseast1
Showing 1 - 20 of 98 Items
Showing 1 - 20 of 98 Items
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Journal Article
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Research

Nationwide retrospective mortality and seroprevalence of SARS-CoV-2 antibodies in Cameroon

Eyong J, Fai KN, Nikolay B, Gignoux EM, Nsaibirini R,  et al.
2023-10-04 • Scientific African
2023-10-04 • Scientific African
BACKGROUND
Although the first year of the COVID-19 pandemic in Africa did not produce the expected catastrophe, the true impact of COVID-19 in the Cameroonian population was unclear....
Journal Article
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Commentary

Moving towards malaria elimination with safer treatment for children with G6PD deficiency

Boum Y II, Moukoko CEE, Parikh S
2023-04-01 • Lancet Infectious Diseases
2023-04-01 • Lancet Infectious Diseases
Journal Article
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Research

Duration of viral suppression and risk of rebound viremia with first-line antiretroviral therapy in rural Uganda

Musinguzi N, Mocello AR, Boum Y II, Hunt PW, Martin JN,  et al.
2016-06-02 • AIDS and Behavior
2016-06-02 • AIDS and Behavior
Little is known about associations between viral suppression, adherence, and duration of prior viral suppression in sub-Saharan Africa. Study participants were from the UARTO study in Mb...
Journal Article
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Research

Factors influencing the return of inactive blood donors in a Cameroonian blood bank

Ndoumba AM, Tagny CT, Nzedzou G, Boum Y II, Mbanya D
2020-04-19 • Transfusion Clinique et Biologique
2020-04-19 • Transfusion Clinique et Biologique
Identify factors that influence the return of donors to increase their loyalty while improving blood safety is crucial in our context. Between October 2017 and April 2018, we conducted a...
Journal Article
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Research

Evaluation of the SD Bioline TB Ag MPT64 test for identification of Mycobacterium tuberculosis complex from liquid cultures in southwestern Uganda

Orikiriza P, Nyehangane D, Atwine D, Kisakye JJ, Kassaza K,  et al.
2017-03-31 • East African Medical Journal
2017-03-31 • East African Medical Journal
BACKGROUND
To confirm presence of Mycobacterium tuberculosis complex, some tuberculosis culture laboratories still rely on para-nitrobenzoic acid (PNB), a traditional technique that ...
Journal Article
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Research

Evaluation of the Deki Reader™, an automated RDT reader and data management device, in a household survey setting in low malaria endemic southwestern Uganda

Oyet C, Roh ME, Kiwanuka G, Orikiriza P, Wade M,  et al.
2017-10-28 • Malaria Journal
2017-10-28 • Malaria Journal
BACKGROUND
Early diagnosis of suspected malaria cases with a rapid diagnostic test (RDT) has been shown to be an effective malaria control tool used in many resource-constrained sett...
Journal Article
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Research

Outcome of children with presumptive tuberculosis in Mbarara, rural Uganda

Bonnet MMB, Nansumba M, Bastard M, Orikiriza P, Kyomugasho N,  et al.
2017-08-02 • Pediatric Infectious Disease Journal
2017-08-02 • Pediatric Infectious Disease Journal
BACKGROUND
Mortality among children with presumptive tuberculosis (TB) empiric TB treatment can be high. We describe the predictors of death among children with presumptive TB, and t...
Journal Article
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Research

Who is telling the story? A systematic review of authorship for infectious disease research conducted in Africa, 1980-2016

Mbaye R, Gebeyehu R, Hossmann S, Mbarga NF, Bih-Neh E,  et al.
2019-10-18 • BMJ Global Health
2019-10-18 • BMJ Global Health
INTRODUCTION
Africa contributes little to the biomedical literature despite its high burden of infectious diseases. Global health research partnerships aimed at addressing Africa-end...
Journal Article
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Research

High incidence of intended partner pregnancy among men living with HIV in rural Uganda: Implications for safer conception services

Kaida A, Kabakyenga JK, Bwana M, Bajunirwe F, Muyindike WR,  et al.
2019-08-15 • Journal of Acquired Immune Deficiency Syndromes (1999)
2019-08-15 • Journal of Acquired Immune Deficiency Syndromes (1999)
Many men with HIV express fertility intentions and nearly half have HIV-uninfected sexual partners. We measured partner pregnancy among a cohort of men accessing antiretroviral therapy (...
Journal Article
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Research

Low Resistance to First and Second Line Anti-Tuberculosis Drugs among Treatment Naive Pulmonary Tuberculosis Patients in Southwestern Uganda

Orikiriza P, Tibenderana B, Siedner MJ, Mueller YK, Byarugaba F,  et al.
2015-02-06 • PLOS One
2015-02-06 • PLOS One
There are limited data on region-specific drug susceptibility of tuberculosis (TB) in Uganda. We performed resistance testing on specimens collected from treatment-naive patients with pu...
Journal Article
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Research

Higher Art Adherence is Associated with Lower Systemic Inflammation in Treatment-Naïve Ugandans Who Achieve Virologic Suppression

Castillo-Mancilla JR, Morrow M, Boum Y II, Byakwaga H, Haberer JE,  et al.
2018-01-16 • Journal of Acquired Immune Deficiency Syndromes (1999)
2018-01-16 • Journal of Acquired Immune Deficiency Syndromes (1999)
Residual systemic inflammation persists despite suppressive antiretroviral therapy (ART) and is associated with non-AIDS clinical outcomes. We aimed to evaluate the association between A...
Journal Article
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Commentary

Burden of disease in francophone Africa 1990-2017: the triple penalty?

Boum Y II, Mburu Y
2020-03-01 • Lancet Global Health
2020-03-01 • Lancet Global Health
Journal Article
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Research

Treated HIV infection and progression of carotid atherosclerosis in rural Uganda: a prospective observational cohort study

Siender M, Bibangambah P, Kim JH, Lankowski A, Chang JL,  et al.
2021-06-15 • Journal of the American Heart Association
2021-06-15 • Journal of the American Heart Association
BACKGROUND
Although ≈70% of the world's population of people living with HIV resides in sub-Saharan Africa, there are minimal prospective data on the contributions of HIV infection t...
Journal Article
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Research

Diagnostic accuracy of the small membrane filtration method for diagnosis of pulmonary tuberculosis in a high HIV prevalence setting

Boum Y II, Kim S, Orikiriza P, Acuña-Villaorduña C, Vinhas S,  et al.
2016-03-30 • Journal of Clinical Microbiology
2016-03-30 • Journal of Clinical Microbiology
Sputum acid-fast bacilli (AFB) smear microscopy has suboptimal sensitivity but remains the most commonly used laboratory test to diagnose pulmonary tuberculosis (TB). We prospectively ev...
Journal Article
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Research

Serologic response to SARS-CoV-2 in an African population

Fai KN, Corine TM, Bebell LM, Mbroingong AB, Nguimbis EBPT,  et al.
2021-07-01 • Scientific African
2021-07-01 • Scientific African
Official case counts suggest Africa has not seen the expected burden of COVID-19 as predicted by international health agencies, and the proportion of asymptomatic patients, disease sever...
Journal Article
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Research

Internalized stigma, depressive symptoms, and the modifying role of antiretroviral therapy: A cohort study in rural Uganda

Bebell LM, Kembabazi A, Musinguzi N, Martin JN, Hunt PW,  et al.
2021-12-01 • SSM - Mental Health
2021-12-01 • SSM - Mental Health
Depression affects over 40% of people with HIV (PHIV) in low- and middle-income countries, and over half of PHIV report HIV-related internalized stigma. However, few longitudinal studies...
Journal Article
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Research

Characteristics of human encounters and social mixing patterns relevant to infectious diseases spread by close contact: a survey in Southwest Uganda

le Polain de Waroux O, Cohuet S, Ndazima D, Kucharski AJ, Juan-Giner A,  et al.
2018-04-11 • BMC Infectious Diseases
2018-04-11 • BMC Infectious Diseases
BACKGROUND
Quantification of human interactions relevant to infectious disease transmission through social contact is central to predict disease dynamics, yet data from low-resource ...
Journal Article
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Research

A Worldwide Map of Plasmodium Falciparum K13-Propeller Polymorphisms

Ménard D, Khim N, Beghain J, Adegnika AA, Alam MS,  et al.
2016-06-23 • New England Journal of Medicine
2016-06-23 • New England Journal of Medicine
Recent gains in reducing the global burden of malaria are threatened by the emergence of Plasmodium falciparum resistance to artemisinins. The discovery that mutations in portions of a P...
Journal Article
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Research

Xpert MTB/RIF diagnosis of childhood tuberculosis from sputum and stool samples in a high TB-HIV-prevalent setting

Orikiriza P, Nansumba M, Nyehangane D, Bastard M, Mugisha IT,  et al.
2018-05-08 • European Journal of Clinical Microbiology and Infectious Diseases
2018-05-08 • European Journal of Clinical Microbiology and Infectious Diseases
The Xpert MTB/RIF assay is a major advance for diagnosis of tuberculosis (TB) in high-burden countries but is limited in children by their difficulty to produce sputum. We investigated T...
Journal Article
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Research

CD4+ cell count at antiretroviral therapy initiation and economic restoration in rural Uganda

Venkataramani AS, Thirumurthy H, Haberer JE, Boum Y II, Siedner MJ,  et al.
2014-01-08 • AIDS
2014-01-08 • AIDS
OBJECTIVE
To determine whether earlier initiation of antiretroviral therapy (ART) is associated with better economic outcomes.

DESIGN
Prospective cohort study of HIV-pos...