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Copyright © Médecins Sans Frontières
v2.1.5153.produseast1
Showing 1 - 19 of 19 Items
Showing 1 - 19 of 19 Items
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Journal Article
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Research

Duration of viral suppression and risk of rebound viremia with first-line antiretroviral therapy in rural Uganda

Musinguzi N, Mocello AR, Boum Y II, Hunt PW, Martin JN,  et al.
2016-06-02 • AIDS and Behavior
2016-06-02 • AIDS and Behavior
Little is known about associations between viral suppression, adherence, and duration of prior viral suppression in sub-Saharan Africa. Study participants were from the UARTO study in Mb...
Journal Article
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Research

High incidence of intended partner pregnancy among men living with HIV in rural Uganda: Implications for safer conception services

Kaida A, Kabakyenga JK, Bwana M, Bajunirwe F, Muyindike WR,  et al.
2019-08-15 • Journal of Acquired Immune Deficiency Syndromes (1999)
2019-08-15 • Journal of Acquired Immune Deficiency Syndromes (1999)
Many men with HIV express fertility intentions and nearly half have HIV-uninfected sexual partners. We measured partner pregnancy among a cohort of men accessing antiretroviral therapy (...
Journal Article
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Research

Higher Art Adherence is Associated with Lower Systemic Inflammation in Treatment-Naïve Ugandans Who Achieve Virologic Suppression

Castillo-Mancilla JR, Morrow M, Boum Y II, Byakwaga H, Haberer JE,  et al.
2018-01-16 • Journal of Acquired Immune Deficiency Syndromes (1999)
2018-01-16 • Journal of Acquired Immune Deficiency Syndromes (1999)
Residual systemic inflammation persists despite suppressive antiretroviral therapy (ART) and is associated with non-AIDS clinical outcomes. We aimed to evaluate the association between A...
Journal Article
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Research

Treated HIV infection and progression of carotid atherosclerosis in rural Uganda: a prospective observational cohort study

Siender M, Bibangambah P, Kim JH, Lankowski A, Chang JL,  et al.
2021-06-15 • Journal of the American Heart Association
2021-06-15 • Journal of the American Heart Association
BACKGROUND
Although ≈70% of the world's population of people living with HIV resides in sub-Saharan Africa, there are minimal prospective data on the contributions of HIV infection t...
Journal Article
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Research

Internalized stigma, depressive symptoms, and the modifying role of antiretroviral therapy: A cohort study in rural Uganda

Bebell LM, Kembabazi A, Musinguzi N, Martin JN, Hunt PW,  et al.
2021-12-01 • SSM - Mental Health
2021-12-01 • SSM - Mental Health
Depression affects over 40% of people with HIV (PHIV) in low- and middle-income countries, and over half of PHIV report HIV-related internalized stigma. However, few longitudinal studies...
Journal Article
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Research

CD4+ cell count at antiretroviral therapy initiation and economic restoration in rural Uganda

Venkataramani AS, Thirumurthy H, Haberer JE, Boum Y II, Siedner MJ,  et al.
2014-01-08 • AIDS
2014-01-08 • AIDS
OBJECTIVE
To determine whether earlier initiation of antiretroviral therapy (ART) is associated with better economic outcomes.

DESIGN
Prospective cohort study of HIV-pos...
Journal Article
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Research

Sociocultural and Structural Factors Contributing to Delays in Treatment for Children with Severe Malaria: A Qualitative Study in Southwestern Uganda

Sundararajan R, Mwanga-Amumpaire J, Adrama H, Tumuhairwe J, Mbabazi S,  et al.
2015-03-23 • American Journal of Tropical Medicine and Hygiene
2015-03-23 • American Journal of Tropical Medicine and Hygiene
Malaria is a leading cause of pediatric mortality, and Uganda has the highest incidences in the world. Increased morbidity and mortality are associated with delays to care. This qualitat...
Journal Article
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Research

Inhaled nitric oxide as an adjunctive treatment for cerebral malaria in children: a phase II randomized open-label clinical trial

Mwanga-Amumpaire J, Carroll R, Baudin E, Kemigisha E, Nampijja D,  et al.
2015-07-24 • Open Forum Infectious Diseases
2015-07-24 • Open Forum Infectious Diseases
Abstract
Background.  Children with cerebral malaria (CM) have high rates of mortality and neurologic sequelae. Nitric oxide (NO) meta...
Journal Article
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Research

Antimicrobial-resistant infections among postpartum women at a Ugandan referral hospital

Bebell LM, Ngonzi J, Bazira J, Fajardo Y, Boatin AA,  et al.
2017-04-13 • PLOS One
2017-04-13 • PLOS One
INTRODUCTION
Puerperal sepsis causes 10% of maternal deaths in Africa, but prospective studies on incidence, microbiology and antimicrobial resistance are lacking.

METHODS
Journal Article
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Research

The kynurenine pathway of tryptophan catabolism, CD4+ T-cell recovery, and mortality among HIV-infected Ugandans initiating antiretroviral therapy

Byakwaga H, Boum Y II, Huang Y, Muzoora C, Kembabazi A,  et al.
2014-02-28 • Journal of Infectious Diseases
2014-02-28 • Journal of Infectious Diseases
Human immunodeficiency virus (HIV) infection-induced indoleamine 2,3-dioxygenase-1 (IDO) expression in activated monocytes and dendritic cells catabolizes tryptophan to kynurenine and ot...
Journal Article
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Research

Implementation of low-cost, point-of-care cardiovascular diagnostics by non-healthcare professionals in rural Uganda

Kim JH, Hemphill LC, Boum Y II, Bangsberg DR, Siedner MJ
2015-03-12 • Annals of Global Health
2015-03-12 • Annals of Global Health
BACKGROUND
Non-communicable diseases (NCDs) account for the majority of adult deaths worldwide, and 80% of these deaths occur in
low and middle-income countries (LMICs). The burd...
Journal Article
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Research

Depression During Pregnancy and the Postpartum Among HIV-Infected Women on Antiretroviral Therapy in Uganda

Kaida A, Matthews LT, Ashaba S, Tsai AC, Kanters S,  et al.
2014-12-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
2014-12-01 • Journal of Acquired Immune Deficiency Syndromes (1999)
Among HIV-infected women, perinatal depression compromises clinical, maternal, and child health outcomes. Antiretroviral therapy (ART) is associated with lower depression symptom severit...
Journal Article
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Research

Distribution and performance of cardiovascular risk scores in a mixed population of HIV-infected and community-based HIV-uninfected individuals in Uganda

Muiru AN, Bibangambah P, Hemphill LC, Sentongo R, Kim JH,  et al.
2018-04-11 • Journal of Acquired Immune Deficiency Syndromes (1999)
2018-04-11 • Journal of Acquired Immune Deficiency Syndromes (1999)
BACKGROUND
The utility and validity of cardiovascular diseases (CVD) risk scores are not well studied in sub-Saharan Africa. We compared and correlated CVD risk scores with carotid i...
Journal Article
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Research

Trends in one-year cumulative incidence of death between 2005 and 2013 among patients initiating antiretroviral therapy in Uganda

Bebell LM, Siedner MJ, Musinguzi N, Boum Y II, Bwana BM,  et al.
2016-09-20 • International Journal of STD and AIDS
2016-09-20 • International Journal of STD and AIDS
Recent ecological data demonstrate improving outcomes for HIV-infected people in sub-Saharan Africa. Recently, Uganda has experienced a resurgence in HIV incidence and prevalenc...
Journal Article
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Review

Re-Inventing Adherence: Toward a Patient-Centered Model of Care for Drug-Resistant Tuberculosis and HIV

ODonnell MR, Daftary A, Frick M, Hirsch-Moverman Y, Amico KR,  et al.
2016-04-01 • International Journal of Tuberculosis and Lung Disease
2016-04-01 • International Journal of Tuberculosis and Lung Disease
Despite renewed focus on molecular tuberculosis (TB) diagnostics and new antimycobacterial agents, treatment outcomes for patients co-infected with drug-resistant TB and human immunodefi...
Journal Article
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Research

Declining prevalence of probable depression among patients presenting for antiretroviral therapy in rural Uganda: the role of early treatment initiation

Chan BT, Weiser SD, Boum Y II, Haberer JE, Kembabazi A,  et al.
2014-05-01 • AIDS and Behavior
2014-05-01 • AIDS and Behavior
Little is known about trends in depression at antiretroviral therapy (ART) initiation among people living with HIV (PLHIV) in low- and middle-income countries. We used data from an ongoi...
Journal Article
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Research

Altered Virome and Bacterial Microbiome in Human Immunodeficiency Virus-Associated Acquired Immunodeficiency Syndrome

Monaco CL, Gootenberg DB, Zhao G, Handley SA, Ghebremichael MS,  et al.
2016-03-09 • Cell Host and Microbe
2016-03-09 • Cell Host and Microbe
Human immunodeficiency virus (HIV) infection is associated with increased intestinal translocation of microbial products and enteropathy as well as alterations in gut bacterial communiti...
Journal Article
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Research

Mean CD4 cell count changes in patients failing a first-line antiretroviral therapy in resource-limited settings

Calmy A, Balestre E, Bonnet F, Boulle AM, Sprinz E,  et al.
2012-12-01 • BMC Infectious Diseases
2012-12-01 • BMC Infectious Diseases
Changes in CD4 cell counts are poorly documented in individuals with low or moderate-level viremia while on antiretroviral treatment (ART) in resource-limited settings. We assessed the i...
Journal Article
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Research

Comparison of Self-Reported Alcohol Consumption to Phosphatidylethanol Measurement among HIV-Infected Patients Initiating Antiretroviral Treatment in Southwestern Uganda

Bajunirwe F, Haberer JE, Boum Y II, Hunt PW, Mocello R,  et al.
2014-12-01 • PLOS One
2014-12-01 • PLOS One
Alcohol consumption among HIV-infected patients may accelerate HIV disease progression or reduce antiretroviral therapy adherence. Self-reported alcohol use is frequently under-reported ...