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Showing 1 - 20 of 30 Items
Showing 1 - 20 of 30 Items
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Journal Article
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Research

Neglected etiologies of prolonged febrile illnesses in tropical and subtropical regions: A systematic review

Musumeci S, Kruse A, Chappuis F, Ostergaard Jensen T, Alcoba G
2024-06-21 • PLOS Neglected Tropical Diseases
2024-06-21 • PLOS Neglected Tropical Diseases
BACKGROUND
Febrile illnesses that persist despite initial treatment are common clinical challenges in (sub)tropical low-resource settings. Our aim is to review infectious etiologies ...
Conference Material
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Slide Presentation

Efficacy and safety of 14-day treatment with paromomycin and miltefosine for primary visceral leishmaniasis in eastern Africa: non-inferiority trial

Solomos A, Musa AM, Mbui J, Mohammed R, Olobo J,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023
Conference Material
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Abstract

Efficacy and safety of 14-day treatment with paromomycin and miltefosine for primary visceral leishmaniasis in eastern Africa: non-inferiority trial

Solomos A, Musa AM, Mbui J, Mohammed R, Olobo J,  et al.
2023-06-07 • MSF Scientific Day International 2023
2023-06-07 • MSF Scientific Day International 2023
INTRODUCTION
The parasitic disease visceral leishmaniasis (VL) is most commonly caused by Leishmania donovani in eastern Africa, currently the region with highest burden worldwide. C...
Journal Article
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Research

A global core outcome measurement set for snakebite clinical trials

Abouyannis M, Esmail H, Hamaluba M, Ngama M, Mwangudzah H,  et al.
2023-02-01 • Lancet Global Health
2023-02-01 • Lancet Global Health
Snakebite clinical trials have often used heterogeneous outcome measures and there is an urgent need for standardisation. A globally representative group of key stakeholders came togethe...
Journal Article
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Research

Définition d'un jeu universel de critères de décision de base pour les essais cliniques sur les morsures de serpent

Abouyannis M, Esmail H, Hamaluba M, Ngama M, Mwangudzah H,  et al.
2023-02-01 • Médecine tropicale et santé internationale
2023-02-01 • Médecine tropicale et santé internationale
CONTEXTE
Les essais cliniques sur les morsures de serpent ont souvent utilisé des critères de décision hétérogènes qui demandent à être standardisés.

MÉTHODE
Un groupe d...
Journal Article
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Commentary

Snakebite envenoming at MSF: A decade of clinical challenges and antivenom access issues

Potet J, Singh SN, Ritmeijer KKD, Sisay K, Alcoba G,  et al.
2022-12-21 • Toxicon: X
2022-12-21 • Toxicon: X
The medical humanitarian organization Médecins Sans Frontières (MSF) provides medical care in more than 70 countries and admits more than 7000 cases of snakebite in its facilities each y...
Journal Article
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Research

Paromomycin and miltefosine combination as an alternative to treat patients with visceral leishmaniasis in Eastern Africa: A randomized, controlled, multicountry trial

Musa AM, Mbui J, Mohammed R, Olobo J, Ritmeijer KKD,  et al.
2022-09-27 • Clinical Infectious Diseases
2022-09-27 • Clinical Infectious Diseases
BACKGROUND
This study aimed to determine whether paromomycin plus miltefosine (PM/MF) is noninferior to sodium stibogluconate plus paromomycin (SSG/PM) for treatment of primary visce...
Journal Article
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Research

An artificial intelligence model to identify snakes from across the world: Opportunities and challenges for global health and herpetology

Bolon I, Picek L, Durso AM, Alcoba G, Chappuis F,  et al.
2022-08-15 • PLOS Neglected Tropical Diseases
2022-08-15 • PLOS Neglected Tropical Diseases
BACKGROUND
Snakebite envenoming is a neglected tropical disease that kills an estimated 81,000 to 138,000 people and disables another 400,000 globally every year. The World Health Or...
Journal Article
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Research

"Kala-Azar is a Dishonest Disease": Community Perspectives on Access Barriers to Visceral Leishmaniasis (Kala-Azar) Diagnosis and Care in Southern Gadarif, Sudan

Sunyoto T, Adam GK, Atia AM, Hamid Y, Babiker RA,  et al.
2018-02-22 • American Journal of Tropical Medicine and Hygiene
2018-02-22 • American Journal of Tropical Medicine and Hygiene
Early diagnosis and treatment is the principal strategy to control visceral leishmaniasis (VL), or kala-azar in East Africa. As VL strikes remote rural, sparsely populated areas, kala-az...
Journal Article
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Research

Novel transdisciplinary methodology for cross-sectional analysis of snakebite epidemiology at national scale

Alcoba G, Ochoa C, Martins SB, Ruiz de Castañeda R, Bolon I,  et al.
2021-02-12 • PLOS Neglected Tropical Diseases
2021-02-12 • PLOS Neglected Tropical Diseases
BACKGROUND
Worldwide, it is estimated that snakes bite 4.5-5.4 million people annually, 2.7 million of which are envenomed, and 81,000-138,000 die. The World Health Organization repo...
Journal Article
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Research

Vulnerability to snakebite envenoming: a global mapping of hotspots

Longbottom J, Shearer FM, Devine M, Alcoba G, Chappuis F,  et al.
2018-07-12 • Lancet
2018-07-12 • Lancet
Snakebite envenoming is a frequently overlooked cause of mortality and morbidity. Data for snake ecology and existing snakebite interventions are scarce, limiting accurate burden estimat...
Conference Material
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Poster

Outcomes and effectiveness of antivenom treatments in snakebite patients in north-west Ethiopia: retrospective cohort

Steegemans IM, Sisay K, Nshimiyimana E, Gebrewold G, Piening T,  et al.
2021-05-18 • MSF Scientific Days International 2021: Research
2021-05-18 • MSF Scientific Days International 2021: Research
Journal Article
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Commentary

Snakebite and snake identification: empowering neglected communities and health-care providers with AI

De Castaneda RR, Durso AM, Ray N, Fernandez JL, Williams DJ,  et al.
2019-09-01 • Lancet Digital Health
2019-09-01 • Lancet Digital Health
Journal Article
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Research

Snakebite epidemiology and health-seeking behavior in Akonolinga health district, Cameroon: Cross-sectional study

Alcoba G, Chabloz M, Eyong J, Wanda F, Ochoa C,  et al.
2020-06-25 • PLOS Neglected Tropical Diseases
2020-06-25 • PLOS Neglected Tropical Diseases
BACKGROUND
Snakebite envenoming causes 81,000-138,000 annual human deaths and pain, terror, or disability in 4.5-5.4 million victims. Accurate community-based epidemiological data is...
Journal Article
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Commentary

Perspectives from MSF snakebite programme implementation in Agok, Abyei region, South Sudan

Said M, Valdespino E, Baba SP, Lako RL, Malm A,  et al.
2020-11-01 • South Sudan Medical Journal
2020-11-01 • South Sudan Medical Journal
INTRODUCTION
Snakebite is a neglected tropical disease affecting around five million people, causing more than 100,000 annual deaths, as well as serious disabilities; however, access...
Journal Article
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Commentary

Antivenoms for Snakebite Envenoming: What Is in the Research Pipeline?

Alirol E, Lechevalier P, Zamatto F, Chappuis F, Alcoba G,  et al.
2015-09-10 • PLOS Neglected Tropical Diseases
2015-09-10 • PLOS Neglected Tropical Diseases
Journal Article
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Research

Knowledge, attitude and practices of snakebite management amongest health workers in Cameroon: Need for continuous training and capacity building

Taieb F, Dub T, Madec Y, Tondeur L, Chippaux JP,  et al.
2018-10-25 • PLOS Neglected Tropical Diseases
2018-10-25 • PLOS Neglected Tropical Diseases
Snakebite has only recently been recognized as a neglected tropical disease by the WHO. Knowledge regarding snakebites and its care is poor both at the population level, and at the healt...
Journal Article
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Review

Access to antivenoms in the developing world: a multidisciplinary analysis

Potet J, Beran D, Ray N, Alcoba G, Habib AG,  et al.
2021-10-26 • Toxicon: X
2021-10-26 • Toxicon: X
Access to safe, effective, quality-assured antivenom products that are tailored to endemic venomous snake species is a crucial component of recent coordinated efforts to reduce the globa...
Journal Article
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Letter

COVID-19 symptoms: longitudinal evolution and persistence in outpatient settings

Nehme M, Braillard O, Alcoba G, Perone SA, Courvoisier D,  et al.
2021-05-01 • Annals of Internal Medicine
2021-05-01 • Annals of Internal Medicine
Journal Article
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Research

Estimating and predicting snakebite risk in the Terai region of Nepal through a high-resolution geospatial and One Health approach

Ochoa C, Pittavino M, Martins SB, Alcoba G, Bolon I,  et al.
2021-12-13 • Scientific Reports
2021-12-13 • Scientific Reports
Most efforts to understand snakebite burden in Nepal have been localized to relatively small areas and focused on humans through epidemiological studies. We present the outcomes of a geo...