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Diphtheria | Collections | MSF Science Portal
Diphtheria

Diphtheria

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Neglected tropical diseases

Neglected tropical diseases

Each year hundreds of thousands of people die from a neglected tropical disease, while many more suffer serious illness or lifelong disability. Yet as we mark World Neglected Tropical Diseases (NTD) Day on 30th January, global progress towards eliminating these diseases is threatened by shifting global health priorities and declining investment in the wake of the Covid-19 pandemic.


The content collection linked below offers a snapshot of MSF’s work on managing some of the most deadly NTDs, finding better tools and models of care for highly affected populations, and advocating for greater access to care and increased global funding. Several authors describe our programs and lessons learned from a decade of treating snakebite victims in sub-Saharan Africa. Two studies evaluate shorter, less toxic treatment for visceral leischmaniasis, while a policy analysis proposes critical steps towards eliminating this horrific disease in East Africa. Last, reports from Sokoto, Nigeria describe the collaborative development of a comprehensive model of care for noma.

Mental health in humanitarian settings

Mental health in humanitarian settings
MSF Paediatric Days 2024 abstracts

MSF Paediatric Days 2024 abstracts
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Complex humanitarian emergencies and other low-resource settings can be exceedingly difficult places to provide quality mental health (MH) care. Yet these environments also often have a high burden of mental health care needs. This collection presents a set of articles describing how MSF teams have adapted and evaluated ways of bringing clinically impactful MH care to neglected communities and patients—from forcibly displaced populations in northern Nigeria to Syrian refugees in Lebanon and typhoon survivors in the Philippines. It also highlights work on developing new tools for providing clinical supervision and for identifying those patients most in need of care in fragile settings, and on new approaches to delivering MH services during the Covid-19 pandemic.
On 3-4 May in Nairobi, Kenya, MSF gathered staff from our projects with experts from academia, clinical practice and the non-governmental sector to consider key issues in humanitarian paediatrics. These included: Vaccination and vaccine-preventable diseases: Amid post-Covid-19 global setbacks in child vaccination coverage, sessions spotlighted recent increases in vaccine-preventable disease outbreaks, potential new vaccination strategies and emergency responses, and MSF’s role in vaccine advocacy and catch-up campaigns. Nutrition: Talks covered the nexus of nutrition with other key conference topics, the latest malnutrition guidance and tools, and MSF’s priorities in nutritional care. Paediatric HIV: With half of all HIV-positive children globally not receiving antiretroviral therapy, presenters reviewed the latest paediatric testing/treatment recommendations and discussed barriers and potential solutions to implementation, nutritional challenges in children with HIV, and systems strengthening for preventing and monitoring paediatric HIV. Click below to read the abstracts. And stay tuned for more conference content, coming soon.
Journal Article
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Short Report

Diphtheria in Europe

Mangion JP, Mancini S, Bachy C, de Weggheleire A, Zamatto F
2023-06-21 • Public Health Action
2023-06-21 • Public Health Action
A rising number of diphtheria cases were recorded in Europe in 2022, including in Belgium, within the newly arriving young migrant population. In October 2022, Médecins Sans Frontières (...
Journal Article
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Research

Diphtheria antitoxin administration, outcomes, and safety: response to a diphtheria outbreak in Cox’s Bazar, Bangladesh

Eisenberg N, Panunzi I, Wolz A, Burzio C, Cilliers A,  et al.
2021-10-05 • Clinical Infectious Diseases
2021-10-05 • Clinical Infectious Diseases
BACKGROUND
Diphtheria has re-emerged over the past several years. There is a paucity of data on the administration and safety of diphtheria antitoxin (DAT), the standard treatment fo...
Journal Article
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Research

Evaluation of community based surveillance in the Rohingya refugee camps in Cox’s Bazar, Bangladesh, 2019

Van Boetzelaer E, Chowdhury SM, Etsay B, Faruque A, Lenglet AD,  et al.
2020-12-23 • PLOS One
2020-12-23 • PLOS One
BACKGROUND
Following an influx of an estimated 742,000 Rohingya refugees in Bangladesh, Médecins sans Frontières (MSF) established an active indicator-based Community Based Surveilla...
Journal Article
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Commentary

Caring for Rohingya refugees with diphtheria and measles: on the ethics of humanity

Asgary R
2020-03-01 • Annals of Family Medicine
2020-03-01 • Annals of Family Medicine
Hundreds of thousands of Rohingya refugees arrived in Bangladesh within weeks in fall 2017, quickly forming large settlements without any basic support. Humanitarian first responders pro...
Journal Article
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Review

Clinical and epidemiological aspects of diphtheria: a systematic review and pooled analysis

Truelove SA, Keegan LT, Moss WJ, Chaisson LH, Macher E,  et al.
2019-08-19 • Clinical Infectious Diseases
2019-08-19 • Clinical Infectious Diseases
BACKGROUND
Diphtheria, once a major cause of childhood morbidity and mortality, all but disappeared following introduction of diphtheria vaccine. Recent outbreaks highlight the risk ...
Conference Material
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Poster

Diphtheria in an emergency outbreak setting: a clinical and epidemiological analysis for children and adults, Bangladesh

Sikder E, del Barrio BV, Firuz W, Khatoon R, Opstrup A,  et al.
2019-04-29 • MSF Scientific Days International 2019
2019-04-29 • MSF Scientific Days International 2019
Journal Article
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Research

Real-time analysis of the diphtheria outbreak in forcibly displaced Myanmar nationals in Bangladesh

Finger F, Funk S, White K, Siddqui MR, Edmunds KL,  et al.
2019-03-12 • BMC Medicine
2019-03-12 • BMC Medicine
Between August and December 2017, more than 625,000 Rohingya from Myanmar fled into Bangladesh, settling in informal makeshift camps in Cox’s Bazar district and joining 212,000 Rohingya ...
Protocol
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Research Protocol

Vaccination coverage survey for diphtheria, Streptococcus pneumoniae, polio and tetanus in Rohingya refugee settlements in Ukhiya and Teknaf Upazilas, Cox’s Bazar, Bangladesh

Pereboom M, White K, Van Leeuwen C, Siddiqui R, Guzek J,  et al.
2018-07-01
2018-07-01
OBJECTIVES

PRIMARY OBJECTIVES
a) To describe the vaccine coverage (penta / dT) in children aged 6 months to 14 years for diphtheria in the Rohingya Settlement Camps;
Journal Article
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Review

The preventable tragedy of diphtheria in the 21st century

Blumberg LH, Prieto MA, Diaz JV, Blanco MJ, Valle B,  et al.
2018-06-08 • International Journal of Infectious Diseases
2018-06-08 • International Journal of Infectious Diseases
Journal Article
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Research

Diphtheria outbreak with high mortality in northeastern Nigeria

Besa NC, Coldiron ME, Bakri A, Raji A, Nsuami MJ,  et al.
2013-07-18 • Epidemiology and Infection
2013-07-18 • Epidemiology and Infection
SUMMARY A diphtheria outbreak occurred from February to November 2011 in the village of Kimba and its surrounding settlements, in Borno State, northeastern Nigeria. We conducted a retros...