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Diphtheria | Collections | MSF Science Portal
Diphtheria

Diphtheria

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Diabetes care in humanitarian settings
Diabetes care in humanitarian settings
Diabetes affect hundreds of millions of people worldwide, a large majority of them living in low- and middle-income countries. Yet finding effective strategies, tools and policies for effectively managing this chronic illness—especially amid war, displacement or exclusion from care—is a neglected area of humanitarian medicine. Here we present a cross-section of work on this front by MSF and collaborators. Several studies assess the shift towards community-based, nurse-led models of care in rural settings. Others explore obstacles to diabetes care for war refugees living in camps in Jordan or Lebanon, highlighting how health programs can adapt to their needs. The demonstration that insulin retains potency for 30 days if cooled without refrigeration is opening doors to more patient self-management, as a case study in remote South Sudan shows. At the same time, MSF and others call for regulatory and financing policies that make diabetes medications and supplies cheaper, better adapted to humanitarian settings, and far more available to patients whose lives depend on them.
Snakebite envenoming: a neglected health crisis
Snakebite envenoming: a neglected health crisis

Every year 2 million or more people fall victim to snakebite envenoming, mostly in poor, rural communities of Africa, Asia and Latin America. Between 83,000—138,000 of them die, while hundreds of thousands more suffer debilitating long-term complications or disabilities.


Although some antivenom medicines are highly effective when used promptly and appropriately, many snakebite victims get no treatment at all. Those who do may receive antivenoms which don’t work against the type of snake that bit them, or were not rigorously tested for safety and effectiveness.


To mark World Snakebite Awareness Day on September 19th, the Collection linked below brings together recent MSF work on this highly neglected disease. Several articles and conference presentations help fill evidence gaps on the burden of disease and its impacts or on treatment outcomes with specific antivenoms. Others examine how to tackle the formidable challenges of availability and affordability, the absence of regulatory oversight for making, testing and registering antivenoms, and the anemic R&D pipeline for new products—all of which impede access for patients to safe, effective treatment tailored to local snake species.

World Hand Hygiene Day 2023
World Hand Hygiene Day 2023
"Clean hands, safe care" is the theme of this year's World Hand Hygiene Day. At MSF, we know that Hand Hygiene is the simplest and best way to prevent the transmission of infections in our facilities. This collection features some lessons learned about hand hygiene and infection, prevention, & control (IPC) in MSF projects, especially in resource-constrained environments in the Sahel, and in the era of COVID-19.
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Journal Article
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Short Report

Diphtheria in Europe

Mangion JP, Mancini S, Bachy C, de Weggheleire A, Zamatto F
2023-06-21 • Public Health Action
2023-06-21 • Public Health Action
A rising number of diphtheria cases were recorded in Europe in 2022, including in Belgium, within the newly arriving young migrant population. In October 2022, Médecins Sans Frontières (...
Journal Article
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Research

Diphtheria antitoxin administration, outcomes, and safety: response to a diphtheria outbreak in Cox’s Bazar, Bangladesh

Eisenberg N, Panunzi I, Wolz A, Burzio C, Cilliers A,  et al.
2021-10-05 • Clinical Infectious Diseases
2021-10-05 • Clinical Infectious Diseases
BACKGROUND
Diphtheria has re-emerged over the past several years. There is a paucity of data on the administration and safety of diphtheria antitoxin (DAT), the standard treatment fo...
Journal Article
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Research

Evaluation of community based surveillance in the Rohingya refugee camps in Cox’s Bazar, Bangladesh, 2019

Van Boetzelaer E, Chowdhury SM, Etsay B, Faruque A, Lenglet AD,  et al.
2020-12-23 • PLOS One
2020-12-23 • PLOS One
BACKGROUND
Following an influx of an estimated 742,000 Rohingya refugees in Bangladesh, Médecins sans Frontières (MSF) established an active indicator-based Community Based Surveilla...
Journal Article
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Commentary

Caring for Rohingya refugees with diphtheria and measles: on the ethics of humanity

Asgary R
2020-03-01 • Annals of Family Medicine
2020-03-01 • Annals of Family Medicine
Hundreds of thousands of Rohingya refugees arrived in Bangladesh within weeks in fall 2017, quickly forming large settlements without any basic support. Humanitarian first responders pro...
Journal Article
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Review

Clinical and epidemiological aspects of diphtheria: a systematic review and pooled analysis

Truelove SA, Keegan LT, Moss WJ, Chaisson LH, Macher E,  et al.
2019-08-19 • Clinical Infectious Diseases
2019-08-19 • Clinical Infectious Diseases
BACKGROUND
Diphtheria, once a major cause of childhood morbidity and mortality, all but disappeared following introduction of diphtheria vaccine. Recent outbreaks highlight the risk ...
Conference Material
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Poster

Diphtheria in an emergency outbreak setting: a clinical and epidemiological analysis for children and adults, Bangladesh

Sikder E, del Barrio BV, Firuz W, Khatoon R, Opstrup A,  et al.
2019-04-29 • MSF Scientific Days International 2019
2019-04-29 • MSF Scientific Days International 2019
Journal Article
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Research

Real-time analysis of the diphtheria outbreak in forcibly displaced Myanmar nationals in Bangladesh

Finger F, Funk S, White K, Siddqui MR, Edmunds KL,  et al.
2019-03-12 • BMC Medicine
2019-03-12 • BMC Medicine
Between August and December 2017, more than 625,000 Rohingya from Myanmar fled into Bangladesh, settling in informal makeshift camps in Cox’s Bazar district and joining 212,000 Rohingya ...
Protocol
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Research Protocol

Vaccination coverage survey for diphtheria, Streptococcus pneumoniae, polio and tetanus in Rohingya refugee settlements in Ukhiya and Teknaf Upazilas, Cox’s Bazar, Bangladesh

Pereboom M, White K, Van Leeuwen C, Siddiqui R, Guzek J,  et al.
2018-07-01
2018-07-01
OBJECTIVES

PRIMARY OBJECTIVES
a) To describe the vaccine coverage (penta / dT) in children aged 6 months to 14 years for diphtheria in the Rohingya Settlement Camps;
Journal Article
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Review

The preventable tragedy of diphtheria in the 21st century

Blumberg LH, Prieto MA, Diaz JV, Blanco MJ, Valle B,  et al.
2018-06-08 • International Journal of Infectious Diseases
2018-06-08 • International Journal of Infectious Diseases
Journal Article
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Research

Diphtheria outbreak with high mortality in northeastern Nigeria

Besa NC, Coldiron ME, Bakri A, Raji A, Nsuami MJ,  et al.
2013-07-18 • Epidemiology and Infection
2013-07-18 • Epidemiology and Infection
SUMMARY A diphtheria outbreak occurred from February to November 2011 in the village of Kimba and its surrounding settlements, in Borno State, northeastern Nigeria. We conducted a retros...